D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 63 Citations 13,498 152 World Ranking 4599 National Ranking 2265

Research.com Recognitions

Awards & Achievements

1999 - American Association of Immunologists Lifetime Achievement Award

1999 - AAI Lifetime Achievement Award, American Association of Immunologists

1992 - Member of the National Academy of Sciences

1987 - Fellow of the American Association for the Advancement of Science (AAAS)

1986 - AAI Distinguished Service Award, American Association of Immunologists For his dedication and unique contributions to immunology

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Antibody

His scientific interests lie mostly in Molecular biology, Receptor, Immunoglobulin E, Antibody and Biochemistry. His studies in Molecular biology integrate themes in fields like cDNA library, Alpha chain, Transfection and Affinity labeling. His Receptor study combines topics in areas such as Signal transduction, Kinase and Cell biology.

Immunoglobulin E and Mitogen-activated protein kinase kinase are commonly linked in his work. His Antibody research integrates issues from Molecule and Antigen. His Biochemistry research is multidisciplinary, incorporating elements of Basophil and Histamine.

His most cited work include:

  • The Receptor with High Affinity for Immunoglobulin E (481 citations)
  • Complete structure and expression in transfected cells of high affinity IgE receptor (451 citations)
  • Dimeric immunoglobulin E serves as a unit signal for mast cell degranulation. (313 citations)

What are the main themes of his work throughout his whole career to date?

Henry Metzger spends much of his time researching Receptor, Immunoglobulin E, Biochemistry, Antibody and Molecular biology. His Receptor research incorporates elements of Biophysics and Signal transduction, Phosphorylation, Cell biology. The concepts of his Immunoglobulin E study are interwoven with issues in Mast cell, Immunoglobulin G, Degranulation and Glycoprotein.

His Biochemistry course of study focuses on Myeloma protein and Metabolism and Affinity labeling. His biological study spans a wide range of topics, including Macroglobulin, Molecule, Stereochemistry and Antigen. His research integrates issues of Ige binding, Tyrosine kinase, Mastocytoma and Transfection in his study of Molecular biology.

He most often published in these fields:

  • Receptor (51.37%)
  • Immunoglobulin E (46.99%)
  • Biochemistry (43.17%)

What were the highlights of his more recent work (between 1995-2012)?

  • Receptor (51.37%)
  • Signal transduction (10.38%)
  • Cell biology (14.75%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Receptor, Signal transduction, Cell biology, Phosphorylation and Immunoglobulin E. His research on Receptor concerns the broader Biochemistry. The various areas that Henry Metzger examines in his Phosphorylation study include Tyrosine and Immunoreceptor tyrosine-based activation motif.

His studies deal with areas such as Phosphatase, Computational biology and Ligand as well as Immunoglobulin E. The Kinase study combines topics in areas such as Cell surface receptor and Chinese hamster ovary cell. His LYN study integrates concerns from other disciplines, such as Molecular biology and Tyrosine phosphorylation.

Between 1995 and 2012, his most popular works were:

  • Investigation of Early Events in FcεRI-Mediated Signaling Using a Detailed Mathematical Model (160 citations)
  • An Unusual Mechanism for Ligand Antagonism (147 citations)
  • The Unique Domain as the Site on Lyn Kinase for Its Constitutive Association with the High Affinity Receptor for IgE (111 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Biochemistry
  • Antibody

The scientist’s investigation covers issues in Receptor, Cell biology, Signal transduction, LYN and Phosphorylation. His work deals with themes such as Immunoglobulin E, Kinase and Molecular biology, which intersect with Receptor. His study looks at the relationship between Immunoglobulin E and fields such as Ligand, as well as how they intersect with chemical problems.

His work carried out in the field of Molecular biology brings together such families of science as Cytokine and Mitogen-activated protein kinase kinase. Signal transduction is a subfield of Biochemistry that he studies. His LYN research focuses on subjects like Dephosphorylation, which are linked to Immunoreceptor tyrosine-based activation motif, Syk, Plasma protein binding and Receptor Aggregation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Complete structure and expression in transfected cells of high affinity IgE receptor

U. Blank;C. Ra;L. Miller;K. White.
Nature (1989)

678 Citations

The Receptor with High Affinity for Immunoglobulin E

H Metzger;G Alcaraz;R Hohman;J P Kinet.
Annual Review of Immunology (1986)

637 Citations

Dimeric immunoglobulin E serves as a unit signal for mast cell degranulation.

David M. Segal;Joel D. Taurog;Henry Metzger.
Proceedings of the National Academy of Sciences of the United States of America (1977)

476 Citations

Affinity labeling of a phosphorylcholine binding mouse myeloma protein.

Bruce Chesebro;Henry Metzger.
Biochemistry (1972)

454 Citations

THE INTERACTION OF IgE WITH RAT BASOPHILIC LEUKEMIA CELLS : II. Quantitative Aspects of the Binding Reaction

Anthony Kulczycki;Henry Metzger.
Journal of Experimental Medicine (1974)

398 Citations

CHARACTERIZATION OF A HUMAN MACROGLOBULIN. I. THE MOLECULAR WEIGHT OF ITS SUBUNIT.

Frederick Miller;Henry Metzger.
Journal of Biological Chemistry (1965)

376 Citations

Assessment of compositional relatedness between proteins.

Henry Metzger;Marvin B. Shapiro;James E. Mosimann;Jay E. Vinton.
Nature (1968)

357 Citations

The Receptor with High Affinity for IgE

Henry Metzger.
Immunological Reviews (1992)

355 Citations

Transmembrane signaling: the joy of aggregation.

H Metzger.
Journal of Immunology (1992)

332 Citations

THE INTERACTION OF IgE WITH RAT BASOPHILIC LEUKEMIA CELLS I. EVIDENCE FOR SPECIFIC BINDING OF IgE

Anthony Kulczycki;Chaviva Isersky;Henry Metzger.
Journal of Experimental Medicine (1974)

318 Citations

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