Alison D. O'Brien mainly investigates Microbiology, Escherichia coli, Toxin, Enterobacteriaceae and Shiga-like toxin. Her research in Microbiology intersects with topics in Mutant, Salmonella, Bacteria, In vivo and Virulence. Her study looks at the relationship between Escherichia coli and fields such as Virology, as well as how they intersect with chemical problems.
Alison D. O'Brien combines subjects such as Enterotoxin, Antiserum, Shigella dysenteriae, Kidney and Shiga toxin with her study of Toxin. Her Enterobacteriaceae research incorporates elements of Plasmid and Feces. In her research, HeLa is intimately related to Vero cell, which falls under the overarching field of Shiga-like toxin.
Her scientific interests lie mostly in Microbiology, Escherichia coli, Shiga toxin, Toxin and Virology. Her Microbiology research includes themes of Salmonella, Bacteria, Gene, Virulence and Enterobacteriaceae. Her Escherichia coli study frequently links to other fields, such as Molecular biology.
While the research belongs to areas of Shiga toxin, Alison D. O'Brien spends her time largely on the problem of Antibody, intersecting her research to questions surrounding Lethal dose. Her research integrates issues of Vero cell, Shigella, Enterotoxin and Shigella dysenteriae in her study of Toxin. Her work on Serotype as part of general Virology research is frequently linked to Bloody diarrhea, bridging the gap between disciplines.
The scientist’s investigation covers issues in Microbiology, Shiga toxin, Escherichia coli, Virulence and Virology. She works on Microbiology which deals in particular with Toxin. Her Shiga toxin study combines topics in areas such as Pathogenicity island, Lethal dose and Hemorrhagic colitis.
Her studies in Escherichia coli integrate themes in fields like Vero cell, Monoclonal antibody, Outbreak and In vivo. Her Virulence study integrates concerns from other disciplines, such as Plasmid, Enteroaggregative Escherichia coli, Bacillus anthracis and Bacillus cereus. The various areas that Alison D. O'Brien examines in her Virology study include Bacterial adhesin, In vitro, Antibiotics and Pathogenesis.
Alison D. O'Brien focuses on Microbiology, Shiga toxin, Escherichia coli, Virology and STX2. The study incorporates disciplines such as Lysogenic cycle, Pathogenicity island, Virulence, Hemorrhagic colitis and Bacillus anthracis in addition to Microbiology. Her work in Virulence covers topics such as Anthrax toxin which are related to areas like Toxin.
Her Shiga toxin research is multidisciplinary, incorporating elements of Pathogen, Intestinal epithelium and Genotype. Her work carried out in the field of Escherichia coli brings together such families of science as Immunity, Signal transduction, Hemolysin Proteins, Proinflammatory cytokine and Innate immune system. Her Virology research integrates issues from Epitope, Epithelium, Ames strain and Pathogenesis.
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Shiga and Shiga-like toxins.
Alison D. O'Brien;Randall K. Holmes.
Microbiological Research (1987)
Shiga-like toxin-converting phages from Escherichia coli strains that cause hemorrhagic colitis or infantile diarrhea
AD O'Brien;JW Newland;SF Miller;RK Holmes.
Science (1984)
Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities.
N A Strockbine;L R Marques;J W Newland;H W Smith.
Infection and Immunity (1986)
Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature
Flemming Scheutz;Louise D. Teel;Lothar Beutin;Denis Piérard.
Journal of Clinical Microbiology (2012)
Production of Shigella dysenteriae Type 1-Like Cytotoxin by Escherichia coli
Alison D. O'Brien;Gerald D. LaVeck;Michael R. Thompson;Samuel B. Formal.
The Journal of Infectious Diseases (1982)
Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis.
A. D. O'Brien;V. L. Tesh;A. Donohue-Rolfe;M. P. Jackson.
Current Topics in Microbiology and Immunology (1992)
Nucleotide sequence analysis and comparison of the structural genes for Shiga-like toxin I and Shiga-like toxin II encoded by bacteriophages from Escherichia coli 933
Matthew P. Jackson;Roger J. Neill;Alison D. O'Brien;Randall K. Holmes.
Fems Microbiology Letters (1987)
Genetic control of susceptibility to salmonella typhimurium in mice: role of the lps gene.
A D O'Brien;D L Rosenstreich;I Scher;G H Campbell.
Journal of Immunology (1980)
Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response
Andrew T. Gewirtz;Peter O. Simon;Clare K. Schmitt;Laura J. Taylor.
Journal of Clinical Investigation (2001)
The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model.
M S Donnenberg;S Tzipori;M L McKee;A D O'Brien.
Journal of Clinical Investigation (1993)
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