World's Best Scientists 2026 revealed!
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Microbiology
USA
2026

D-Index & Metrics

Microbiology

D-Index
128
Citations
73717
World Ranking
85
National Ranking
44

Research.com Recognitions

  • 2026 - Research.com Microbiology in United States Leader Award
  • 2025 - Research.com Microbiology in United States Leader Award
  • 2019 - ASM D.C. White Award, American Society for Microbiology
  • 1994 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

James B. Kaper is affiliated with the University of Maryland, Baltimore in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with significant contributions also noted in medicine. Specific subfields include endocrinology, infectious diseases, molecular biology, genetics, and pathology and forensic medicine.

The main topics of their work include:

  • Escherichia coli research studies
  • Viral gastroenteritis research and epidemiology
  • Gut microbiota and health
  • Digestive system and related health
  • Whipple's Disease and Interleukins
  • Antibiotic Resistance in Bacteria
  • Probiotics and Fermented Foods

James B. Kaper has authored several research papers in reputable scientific venues. Recent publications include:

  • Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection, 2020, Gut Microbes
  • Mucosal Immune Profiles Associated with Diarrheal Disease Severity in Shigella- and Enteropathogenic Escherichia coli-Infected Children Enrolled in the Global Enteric Multicenter Study, 2022, mBio
  • Human Epithelial Stem Cell-Derived Colonoid Monolayers as a Model to Study Shiga Toxin-Producing Escherichia coli-Host Interactions, 2021, Methods in molecular biology
  • Coronin-1 is necessary for enteric pathogen-induced transcytosis across human ileal enteroid monolayers expressing M cells, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Cross-Talk between Probiotic Nissle 1917 and Human Colonic Epithelium Affects the Metabolite Composition and Demonstrates Host Antibacterial Effect, 2021, Metabolites

Frequent coauthors who have collaborated with James B. Kaper include:

  • Jennifer Foulke-Abel
  • Mark Donowitz
  • Karol Dokładny
  • Olga Kovbasnjuk
  • Amanda D. Buskirk

Their work is published in journals such as mBio, Gut Microbes, Methods in molecular biology, Metabolites, and bioRxiv (Cold Spring Harbor Laboratory).

James B. Kaper has received awards, including the ASM D.C. White Award from the American Society for Microbiology in 2019 and was named a Fellow of the American Association for the Advancement of Science (AAAS) in 1994.

Best Publications

  • Diarrheagenic Escherichia coli

    James P. Nataro;James B. Kaper

  • Pathogenic Escherichia coli

    James B. Kaper;James P. Nataro;Harry L. T. Mobley

  • Pathogenicity Islands and the Evolution of Microbes

    Jörg Hacker;James B. Kaper

  • Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector.

    M S Donnenberg;J B Kaper

  • A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens.

    Timothy K. McDaniel;Karen G. Jarvis;Michael S. Donnenberg;James B. Kaper

  • A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells.

    Ann E. Jerse;Jun Yu;Ben D. Tall;James B. Kaper

  • Bacteria–host communication: The language of hormones

    Vanessa Sperandio;Alfredo G. Torres;Alfredo G. Torres;Bruce Jarvis;James P. Nataro

  • Enteropathogenic and enterohaemorrhagic Escherichia coli : more subversive elements

    Gad Frankel;Alan D. Phillips;Ilan Rosenshine;Gordon Dougan

  • New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development.

    M M Levine;J B Kaper;R E Black;M L Clements

  • The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69.

    Simon J. Elliott;Leslie A. Wainwright;Timothy K. McDaniel;Karen G. Jarvis

  • Patterns of adherence of diarrheagenic Escherichia coli to HEp-2 cells.

    James P. Nataro;James B. Kaper;Roy Robins-Browne;Valeria Prado

  • Enteropathogenic Escherichia coli contains a putative type III secretion system necessary for the export of proteins involved in attaching and effacing lesion formation

    Karen G. Jarvis;Jorge A. Giron;Ann E. Jerse;Timothy K. McDaniel

  • Vibrio cholerae produces a second enterotoxin, which affects intestinal tight junctions.

    A Fasano;B Baudry;D W Pumplin;S S Wasserman

  • Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two‐component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli

    Vanessa Sperandio;Alfredo G. Torres;James B. Kaper

  • Enteropathogenic Escherichia coli.

    M S Donnenberg;J B Kaper

  • Association of Genomic O Island 122 of Escherichia coli EDL 933 with Verocytotoxin-Producing Escherichia coli Seropathotypes That Are Linked to Epidemic and/or Serious Disease

    Mohamed A. Karmali;Mohamed A. Karmali;Mariola Mascarenhas;Songhai Shen;Kim Ziebell

  • A Vibrio cholerae pathogenicity island associated with epidemic and pandemic strains

    David K. R. Karaolis;Judith A. Johnson;Camella C. Bailey;Edgar C. Boedeker

  • Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli

    Vanessa Sperandio;Jay L. Mellies;William Nguyen;Sooan Shin

  • The Diarrheal Response of Humans to Some Classic Serotypes of Enteropathogenic Escherichia coli is Dependent on a Plasmid Encoding an Enteroadhesiveness Factor

    Myron M. Levine;James P. Nataro;Helge Karch;Mary M. Baldini

  • A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K‐12

    Timothy K. McDaniel;James B. Kaper

  • Cholera

    Unknown

Frequent Co-Authors

Myron M. Levine
Myron M. Levine University of Maryland, Baltimore
James P. Nataro
James P. Nataro University of Virginia
Alfredo G. Torres
Alfredo G. Torres The University of Texas Medical Branch at Galveston
Vanessa Sperandio
Vanessa Sperandio University of Wisconsin–Madison
Michael S. Donnenberg
Michael S. Donnenberg Virginia Commonwealth University
Alessio Fasano
Alessio Fasano Mead Johnson (United States)
Gad Frankel
Gad Frankel Imperial College London
Iruka N. Okeke
Iruka N. Okeke University of Ibadan
Alan D. Phillips
Alan D. Phillips University College London
Mitsuaki Nishibuchi
Mitsuaki Nishibuchi Kyoto University

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