World's Best Scientists 2026 revealed!

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Biology and Biochemistry

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120
Citations
63070
World Ranking
629
National Ranking
401

Medicine

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119
Citations
62941
World Ranking
3849
National Ranking
2107

Overview

Alessio Fasano is affiliated with Massachusetts General Hospital in the United States and specializes primarily in medicine, with significant contributions spanning infectious diseases, molecular biology, gastroenterology, surgery, and epidemiology. Their work integrates clinical and molecular approaches to address complex medical conditions, focusing notably on immune-mediated and gastrointestinal disorders, as well as infectious diseases including SARS-CoV-2.

The scientist's research output includes a wide range of topics such as celiac disease research and management, gut microbiota and health, SARS-CoV-2 and COVID-19 research, COVID-19 impact on reproduction, Helicobacter pylori-related gastroenterology studies, COVID-19 clinical research studies, and Kawasaki disease with coronary complications.

Among recent publications authored or co-authored by Alessio Fasano are:

  • Coronavirus disease 2019 vaccine response in pregnant and lactating women: a cohort study, 2021, American Journal of Obstetrics and Gynecology
  • Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic, 2020, JAMA Network Open
  • All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases, 2020, F1000Research
  • Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Presentation, Infectivity, and Immune Responses, 2020, The Journal of Pediatrics
  • Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier, 2021, Journal of Clinical Investigation

Frequent co-authors collaborating with Fasano include:

  • Lael M. Yonker
  • Andrea G. Edlow
  • Galit Alter
  • Maureen M. Leonard
  • Rosiane Lima

In terms of publication venues, Alessio Fasano has published extensively in:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gastroenterology
  • International Journal of Molecular Sciences
  • The Journal of Pediatrics

Alessio Fasano has also published a book titled Gut Feelings through The MIT Press in 2021.

Best Publications

  • Chronic inflammation in the etiology of disease across the life span

    David Furman;Judith Campisi;Judith Campisi;Eric Verdin;Pedro Carrera-Bastos

  • Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: A large multicenter study

    Alessio Fasano;Irene Berti;Tania Gerarduzzi;Tarcisio Not

  • The Oslo definitions for coeliac disease and related terms

    Jonas F Ludvigsson;Daniel A Leffler;Julio C Bai;Federico Biagi

  • Current approaches to diagnosis and treatment of celiac disease: An evolving spectrum☆

    Alessio Fasano;Carlo Catassi

  • Spectrum of gluten-related disorders: consensus on new nomenclature and classification

    Anna Sapone;Anna Sapone;Julio C Bai;Carolina Ciacci;Jernej Dolinsek

  • Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.

    Ivor D. Hill;Martha H. Dirks;Gregory S. Liptak;Richard B. Colletti

  • Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

    Dae Wook Kang;James B. Adams;Ann C. Gregory;Ann C. Gregory;Thomas Borody

  • Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

    Alessio Fasano

  • Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.

    Madhukumar Venkatesh;Subhajit Mukherjee;Hongwei Wang;Hao Li

  • Celiac disease: a comprehensive current review

    Giacomo Caio;Giacomo Caio;Umberto Volta;Anna Sapone;Anna Sapone;Daniel A. Leffler;Daniel A. Leffler

  • Clinical practice. Celiac disease.

    Alessio Fasano;Carlo Catassi

  • Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease

    Alessio Fasano;Tarcisio Not;Wenle Wang;Sergio Uzzau

  • Vibrio cholerae produces a second enterotoxin, which affects intestinal tight junctions.

    A Fasano;B Baudry;D W Pumplin;S S Wasserman

  • A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease

    Carlo Catassi;Elisabetta Fabiani;Giuseppe Iacono;Cinzia D'Agate

  • Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3.

    Karen M. Lammers;Ruliang Lu;Julie Brownley;Bao Lu

  • Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines

    Sandro Drago;Ramzi El Asmar;Mariarosaria Di Pierro;Maria Grazia Clemente

  • Coronavirus disease 2019 vaccine response in pregnant and lactating women: a cohort study.

    Kathryn J. Gray;Evan A. Bordt;Caroline Atyeo;Elizabeth Deriso

  • Mechanisms of Disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal autoimmune diseases

    Alessio Fasano;Terez Shea-Donohue

  • Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related Disorders

    Carlo Catassi;Julio C. Bai;Bruno Bonaz;Gerd Bouma

  • Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity

    Anna Sapone;Anna Sapone;Karen M Lammers;Vincenzo Casolaro;Vincenzo Casolaro;Marcella Cammarota

Frequent Co-Authors

Carlo Catassi
Carlo Catassi Marche Polytechnic University
Marcelo B. Sztein
Marcelo B. Sztein University of Maryland, Baltimore
Sergio Uzzau
Sergio Uzzau University of Sassari
Peter H.R. Green
Peter H.R. Green Columbia University
Myron M. Levine
Myron M. Levine University of Maryland, Baltimore
Stefanie N. Vogel
Stefanie N. Vogel University of Maryland, Baltimore
James P. Nataro
James P. Nataro University of Virginia
James B. Kaper
James B. Kaper University of Maryland, Baltimore
Vincenzo Casolaro
Vincenzo Casolaro University of Salerno
William W. Eaton
William W. Eaton Johns Hopkins University

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