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Biology and Biochemistry

D-Index
61
Citations
13616
World Ranking
11328
National Ranking
326

Overview

Sergio Uzzau is affiliated with the University of Sassari in Italy. Their research spans several interconnected fields within the life sciences, with a primary focus on Medicine and Biochemistry, Genetics and Molecular Biology. Notable subfields include Molecular Biology, Infectious Diseases, Spectroscopy, Ecology, and Pathology and Forensic Medicine.

Their work tackles multiple main topics, including:

  • Gut microbiota and health
  • Metabolomics and Mass Spectrometry Studies
  • SARS-CoV-2 and COVID-19 Research
  • Advanced Proteomics Techniques and Applications
  • Genomics and Phylogenetic Studies
  • Multiple Sclerosis Research Studies
  • Diet and metabolism studies

Recent publications by Sergio Uzzau cover a range of subjects linked to microbiome research, proteomics, and disease-related immunology. Selected papers include:

  • "Critical Assessment of MetaProteome Investigation (CAMPI): a multi-laboratory comparison of established workflows," 2021, published in Nature Communications
  • "The Metaproteomics Initiative: a coordinated approach for propelling the functional characterization of microbiomes," 2021, published in Microbiome
  • "Comparative Evaluation of MaxQuant and Proteome Discoverer MS1-Based Protein Quantification Tools," 2021, published in Journal of Proteome Research
  • "Effect of Different Disease-Modifying Therapies on Humoral Response to BNT162b2 Vaccine in Sardinian Multiple Sclerosis Patients," 2021, published in Frontiers in Immunology
  • "Inappropriate Nasopharyngeal Sampling for SARS-CoV-2 Detection Is a Relevant Cause of False-Negative Reports," 2020, published in Otolaryngology

Frequent collaborators in Sergio Uzzau's research include:

  • Alessandro Tanca
  • Marcello Abbondio
  • Daniela Pagnozzi
  • Tim Van Den Bossche
  • Jean Armengaud

The scientist frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microbiome
  • npj Biofilms and Microbiomes
  • The Journal of Infection in Developing Countries
  • Journal of Proteome Research

Best Publications

  • Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease

    Alessio Fasano;Tarcisio Not;Wenle Wang;Sergio Uzzau

  • Epitope tagging of chromosomal genes in Salmonella.

    Sergio Uzzau;Nara Figueroa-Bossi;Salvatore Rubino;Lionello Bossi

  • Host adapted serotypes of Salmonella enterica.

    Sergio Uzzau;Derek J. Brown;Timothy S. Wallis;Salvatore Rubino

  • Human zonulin, a potential modulator of intestinal tight junctions

    Wenle Wang;Sergio Uzzau;Simeon E. Goldblum;Alessio Fasano

  • Diabetes and periodontal disease: a case-control study.

    Guglielmo Giuseppe Campus;Abeer Salem;Sergio Uzzau;Edoardo Baldoni

  • Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro.

    Alessio Fasano;Carla Fiorentini;Gianfranco Donelli;Sergio Uzzau

  • Genetic variants regulating immune cell levels in health and disease

    Valeria Orrù;Maristella Steri;Gabriella Sole;Carlo Sidore;Carlo Sidore

  • Variable assortment of prophages provides a transferable repertoire of pathogenic determinants in Salmonella.

    Nara Figueroa‐Bossi;Sergio Uzzau;Danièla Maloriol;Lionello Bossi

  • Modulation of intestinal tight junctions by Zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model.

    A Fasano;S Uzzau

  • Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers

    Carlo Sidore;Fabio Busonero;Andrea Maschio;Eleonora Porcu

  • The bovine milk microbiota: insights and perspectives from -omics studies

    M. F. Addis;A. Tanca;S. Uzzau;G. Oikonomou

  • Zonula Occludens Toxin Structure-Function Analysis IDENTIFICATION OF THE FRAGMENT BIOLOGICALLY ACTIVE ON TIGHT JUNCTIONS AND OF THE ZONULIN RECEPTOR BINDING DOMAIN

    Mariarosaria Di Pierro;Ruliang Lu;Sergio Uzzau;Wenle Wang

  • Low-Pass DNA Sequencing of 1200 Sardinians Reconstructs European Y-Chromosome Phylogeny

    Paolo Francalacci;Laura Cornelia Clotilde Morelli;Andrea Angius;Riccardo Berutti;Riccardo Berutti

  • Proteomic analysis of Salmonella enterica serovar typhimurium isolated from RAW 264.7 macrophages: identification of a novel protein that contributes to the replication of serovar typhimurium inside macrophages.

    Liang Shi;Joshua N. Adkins;James R. Coleman;Athena A. Schepmoes

  • Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactide- co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies

    Vanna Sanna;Anna Maria Roggio;Anna Maria Posadino;Annalisa Cossu

  • A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation.

    Silvia Naitza;Elenora Porcu;Maristella Steri;Dennis Daniel Taub

  • The enterotoxic effect of zonula occludens toxin on rabbit small intestine involves the paracellular pathway.

    Alessio Fasano;Sergio Uzzau;Cara Fiore;Klara Margaretten

  • Generation of high-quality protein extracts from formalin-fixed, paraffin-embedded tissues.

    Maria Filippa Addis;Alessandro Tanca;Daniela Pagnozzi;Salvatore Crobu

  • Targeted Biocompatible Nanoparticles for the Delivery of (−)-Epigallocatechin 3-Gallate to Prostate Cancer Cells

    Vanna Sanna;Gianfranco Pintus;Anna Maria Roggio;Stefania Punzoni

  • Unipept 4.0: Functional Analysis of Metaproteome Data

    Robbert Gurdeep Singh;Alessandro Tanca;Antonio Palomba;Felix Van der Jeugt

Frequent Co-Authors

Alessio Fasano
Alessio Fasano Mead Johnson (United States)
Paolo Moroni
Paolo Moroni University of Milan
Carlo Sidore
Carlo Sidore University of Sassari
Francesco Cucca
Francesco Cucca University of Sassari
Amalia Gastaldelli
Amalia Gastaldelli National Research Council (CNR)
Michael A. Silverman
Michael A. Silverman Children's Hospital of Philadelphia
Gianfranco Pintus
Gianfranco Pintus University of Sassari
David Schlessinger
David Schlessinger National Institutes of Health
Serena Sanna
Serena Sanna National Research Council (CNR)
Gonçalo R. Abecasis
Gonçalo R. Abecasis University of Michigan–Ann Arbor

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