World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
72
Citations
22291
World Ranking
1725
National Ranking
739

Research.com Recognitions

  • 2000 - Oswald Avery Award, Infectious Diseases Society of America

Overview

Michael S. Donnenberg is affiliated with Virginia Commonwealth University in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, as well as Environmental Science, reflecting a multidisciplinary approach to molecular and ecological studies.

The scientist has contributed extensively to subfields such as Molecular Biology, Ecology, Genetics, Endocrinology, and Oncology.

The main research topics covered by Michael S. Donnenberg include:

  • Bacteriophages and microbial interactions
  • Bacterial Genetics and Biotechnology
  • Escherichia coli research studies
  • RNA and protein synthesis mechanisms
  • Peptidase Inhibition and Analysis
  • Biochemical and Structural Characterization
  • Genomics and Phylogenetic Studies

They have been published in a range of scientific venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microbiology and Molecular Biology Reviews
  • EcoSal Plus
  • mBio
  • Expert Opinion on Drug Discovery

Michael S. Donnenberg's recent papers include:

  • "Landmark Discoveries and Recent Advances in Type IV Pilus Research," 2022, Microbiology and Molecular Biology Reviews
  • "Type IV pili of Enterobacteriaceae species," 2024, EcoSal Plus
  • "Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli," 2022, mBio
  • "High throughput and targeted screens for prepilin peptidase inhibitors do not identify common inhibitors of eukaryotic gamma-secretase," 2023, Expert Opinion on Drug Discovery
  • "Revolutionizing Molecular cloning: Introducing FastCloneAssist, a Streamlined Python tool for optimizing primer design in restriction & ligation-independent PCR cloning," 2025, PLoS ONE

Their frequent coauthors include:

  • Pradip Kumar Singh
  • Janay I. Little
  • Jinlei Zhao
  • Montserrat Samsó
  • Ashok R. Nayak

Michael S. Donnenberg was awarded the Oswald Avery Award by the Infectious Diseases Society of America in 2000.

Best Publications

  • Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli

    R. A. Welch;V. Burland;G. Plunkett;P. Redford

  • Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector.

    M S Donnenberg;J B Kaper

  • A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens.

    Timothy K. McDaniel;Karen G. Jarvis;Michael S. Donnenberg;James B. Kaper

  • The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69.

    Simon J. Elliott;Leslie A. Wainwright;Timothy K. McDaniel;Karen G. Jarvis

  • Enteropathogenic Escherichia coli contains a putative type III secretion system necessary for the export of proteins involved in attaching and effacing lesion formation

    Karen G. Jarvis;Jorge A. Giron;Ann E. Jerse;Timothy K. McDaniel

  • Enteropathogenic Escherichia coli.

    M S Donnenberg;J B Kaper

  • The Per regulon of enteropathogenic Escherichia coli: Identification of a regulatory cascade and a novel transcriptional activator, the locus of enterocyte effacement (LEE)-encoded regulator (Ler)

    Jay L. Mellies;Simon J. Elliott;Vanessa Sperandio;Michael S. Donnenberg

  • Molecular Evolution of a Pathogenicity Island from Enterohemorrhagic Escherichia coli O157:H7

    Nicole T. Perna;George F. Mayhew;György Pósfai;Simon Elliott

  • The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model.

    M S Donnenberg;S Tzipori;M L McKee;A D O'Brien

  • Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptake

    I. Rosenshine;M.S. Donnenberg;J.B. Kaper;B.B. Finlay

  • Transcriptome of uropathogenic Escherichia coli during urinary tract infection.

    Jennifer A. Snyder;Brian J. Haugen;Eric L. Buckles;C. Virginia Lockatell

  • Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection.

    M S Donnenberg;C O Tacket;S P James;G Losonsky

  • A plasmid-encoded type IV fimbrial gene of enteropathogenic Escherichia coli associated with localized adherence.

    M. S. Donnenberg;J. A. Girón;J. P. Nataro;J. B. Kaper

  • Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function

    Barry P. McNamara;Athanasia Koutsouris;Colin B. O’Connell;Jean-Philippe Nougayréde

  • A second chromosomal gene necessary for intimate attachment of enteropathogenic Escherichia coli to epithelial cells.

    M. S. Donnenberg;Jun Yu;J. B. Kaper

  • Pathogenesis and evolution of virulence in enteropathogenic and enterohemorrhagic Escherichia coli

    Michael S. Donnenberg;Thomas S. Whittam

  • Type 1 fimbriae and extracellular polysaccharides are preeminent uropathogenic Escherichia coli virulence determinants in the murine urinary tract.

    Farah K. Bahrani-Mougeot;Eric L. Buckles;C. V. Lockatell;J. R. Hebel

  • Interactions between enteropathogenic Escherichia coli and host epithelial cells

    Michael S. Donnenberg;James B. Kaper;B. Brett Finlay

  • EspA, a protein secreted by enteropathogenic Escherichia coli, is required to induce signals in epithelial cells

    Brendan Kenny;Li-Ching Lai;B. Brett Finlay;Michael S. Donnenberg

  • The role of the eaeA gene in diarrhea and neurological complications in a gnotobiotic piglet model of enterohemorrhagic Escherichia coli infection.

    S Tzipori;F Gunzer;M S Donnenberg;L de Montigny

Frequent Co-Authors

James B. Kaper
James B. Kaper University of Maryland, Baltimore
David E. Johnson
David E. Johnson United States Department of Veterans Affairs
Harry L. T. Mobley
Harry L. T. Mobley University of Michigan–Ann Arbor
David A. Rasko
David A. Rasko University of Maryland, Baltimore
Stephen P. James
Stephen P. James National Institutes of Health
James P. Nataro
James P. Nataro University of Virginia
Myron M. Levine
Myron M. Levine University of Maryland, Baltimore
Jean-Philippe Nougayrède
Jean-Philippe Nougayrède INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
B. Brett Finlay
B. Brett Finlay University of British Columbia
Gad Frankel
Gad Frankel Imperial College London

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