World's Best Scientists 2026 revealed!

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Microbiology

D-Index
70
Citations
22097
World Ranking
1905
National Ranking
807

Overview

Vanessa Sperandio is affiliated with the University of Wisconsin-Madison in the United States. Their research focus spans multiple interconnected fields within biomedical science, including biochemistry, genetics, molecular biology, and medicine. A significant portion of their work also relates to endocrinology, molecular biology, infectious diseases, food science, and molecular medicine.

The scientist's publication record includes frequent contributions to noted venues such as mBio, Cell Host & Microbe, Proceedings of the National Academy of Sciences, ACS Central Science, and Cell.

Among their recent publications are:

  • Characterization of Autoinducer-3 Structure and Biosynthesis in E. coli, 2020, ACS Central Science
  • The Serotonin Neurotransmitter Modulates Virulence of Enteric Pathogens, 2020, Cell Host & Microbe
  • l -Arginine sensing regulates virulence gene expression and disease progression in enteric pathogens, 2020, Proceedings of the National Academy of Sciences
  • Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses, 2022, Cell Host & Microbe
  • Endocannabinoids Inhibit the Induction of Virulence in Enteric Pathogens, 2020, Cell

Their frequent collaborators include Aman Kumar, Santiago Cuesta, Regan M. Russell, Fernando H. Martins, and Melissa Ellermann.

Vanessa Sperandio's work covers a range of topics, prominently featuring research on Escherichia coli, gut microbiota and health, probiotics and fermented foods, viral gastroenteritis research and epidemiology, Clostridium difficile and Clostridium perfringens research, antibiotic resistance in bacteria, and bacterial genetics and biotechnology.

  • Escherichia coli research studies
  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Viral gastroenteritis research and epidemiology
  • Clostridium difficile and Clostridium perfringens research
  • Antibiotic Resistance in Bacteria
  • Bacterial Genetics and Biotechnology

The scientist's contribution to research is situated at the intersection of microbial pathogenesis and host interactions, with significant insights into how bacterial signaling and metabolites influence disease processes and host physiology. Their studies frequently address molecular mechanisms of virulence regulation and microbial effects on host health.

Best Publications

  • Anti-virulence strategies to combat bacteria-mediated disease

    David A. Rasko;Vanessa Sperandio

  • Interactions between the microbiota and pathogenic bacteria in the gut

    Andreas J. Bäumler;Vanessa Sperandio

  • Bacteria–host communication: The language of hormones

    Vanessa Sperandio;Alfredo G. Torres;Alfredo G. Torres;Bruce Jarvis;James P. Nataro

  • The Pangenome Structure of Escherichia coli: Comparative Genomic Analysis of E. coli Commensal and Pathogenic Isolates

    David A. Rasko;M. J. Rosovitz;Garry S. A. Myers;Emmanuel F. Mongodin

  • Inter-kingdom signalling: communication between bacteria and their hosts

    David T. Hughes;Vanessa Sperandio

  • Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two‐component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli

    Vanessa Sperandio;Alfredo G. Torres;James B. Kaper

  • The QseC sensor kinase: A bacterial adrenergic receptor

    Marcie B. Clarke;David T. Hughes;Chengru Zhu;Edgar C. Boedeker

  • Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli

    Vanessa Sperandio;Jay L. Mellies;William Nguyen;Sooan Shin

  • Quorum sensing: the many languages of bacteria

    Nicola C. Reading;Vanessa Sperandio

  • Targeting QseC Signaling and Virulence for Antibiotic Development

    David A. Rasko;Cristiano G. Moreira;De Run Li;Nicola C. Reading

  • The Per regulon of enteropathogenic Escherichia coli: Identification of a regulatory cascade and a novel transcriptional activator, the locus of enterocyte effacement (LEE)-encoded regulator (Ler)

    Jay L. Mellies;Simon J. Elliott;Vanessa Sperandio;Michael S. Donnenberg

  • Fucose sensing regulates bacterial intestinal colonization.

    Alline R. Pacheco;Meredith M. Curtis;Jennifer M. Ritchie;Diana Munera

  • Quorum Sensing Is a Global Regulatory Mechanism in Enterohemorrhagic Escherichia coli O157:H7

    Vanessa Sperandio;Alfredo G. Torres;Jorge A. Girón;James B. Kaper

  • The locus of enterocyte effacement (LEE)-encoded regulator controls expression of both LEE- and non-LEE-encoded virulence factors in enteropathogenic and enterohemorrhagic Escherichia coli.

    Simon J. Elliott;Vanessa Sperandio;Jorge A. Girón;Jorge A. Girón;Sooan Shin

  • Enterohemorrhagic E. coli (EHEC) pathogenesis

    Y Nguyen;Vanessa Sperandio

  • The gut commensal Bacteroides thetaiotaomicron exacerbates enteric infection through modification of the metabolic landscape.

    Meredith M. Curtis;Zeping Hu;Claire Klimko;Sanjeev Narayanan

  • Quorum sensing in Escherichia coli and Salmonella.

    Matthew Walters;Vanessa Sperandio

  • Jamming bacterial communication: New approaches for the treatment of infectious diseases

    Jacqueline Njoroge;Vanessa Sperandio

  • Inter-kingdom signaling: chemical language between bacteria and host

    Alline R Pacheco;Vanessa Sperandio

  • Bacterial cell-to-cell signaling in the gastrointestinal tract.

    James B. Kaper;Vanessa Sperandio

  • AI-3 Synthesis Is Not Dependent on luxS in Escherichia coli

    Matthew Walters;Marcelo P. Sircili;Vanessa Sperandio

Frequent Co-Authors

David A. Rasko
David A. Rasko University of Maryland, Baltimore
James B. Kaper
James B. Kaper University of Maryland, Baltimore
Alfredo G. Torres
Alfredo G. Torres The University of Texas Medical Branch at Galveston
Matthew K. Waldor
Matthew K. Waldor Harvard Medical School
Luiz R. Trabulsi
Luiz R. Trabulsi Instituto Butantan
Gad Frankel
Gad Frankel Imperial College London
Sebastian E. Winter
Sebastian E. Winter University of California, Davis
John R. Falck
John R. Falck The University of Texas Southwestern Medical Center
Gary M. Dunny
Gary M. Dunny University of Minnesota
Tetsuya Hayashi
Tetsuya Hayashi Kyushu University

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