World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
89
Citations
42348
World Ranking
12460
National Ranking
6381

Research.com Recognitions

  • 2018 - Member of the National Academy of Medicine (NAM)

Overview

Linda M. Liau is affiliated with the University of California, Los Angeles in the United States. Their research primarily focuses on medicine, with a significant emphasis on biochemistry, genetics, and molecular biology. This scientific work spans multiple subfields including genetics, radiology, nuclear medicine and imaging, molecular biology, cancer research, and immunology.

Their major research topics include glioma diagnosis and treatment, MRI in cancer diagnosis, the application of radiomics and machine learning in medical imaging, immunotherapy and immune responses, cancer related to lipids and metabolism, advanced MRI techniques and applications, and studies on cancer, hypoxia, and metabolism.

Key recent publications by Linda M. Liau include:

  • Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma (2022, JAMA Oncology)

Other influential articles related to their research area, though authored by frequent collaborators or in the broader field of glioblastoma research, include:

  • Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma (2021, Nature Communications)
  • NF1 mutation drives neuronal activity-dependent initiation of optic glioma (2021, Nature)
  • CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis (2023, Cancer Cell)
  • Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank (2020, Neuro-Oncology)

The scientist frequently publishes in specific venues related to neuro-oncology and neuroscience, with the highest number of contributions appearing in:

  • Neuro-Oncology
  • Journal of Neuro-Oncology
  • Neuro-Oncology Advances
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurosurgery

Frequent coauthors collaborating with Linda M. Liau include:

  • Timothy F. Cloughesy
  • Benjamin M. Ellingson
  • Phioanh L. Nghiemphu
  • Richard G. Everson
  • David A. Nathanson

Recognition for their work includes election as a Member of the National Academy of Medicine (NAM) in 2018.

Best Publications

  • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

    Lenny Dang;David W. White;Stefan Gross;Bryson D. Bennett

  • Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

    Ingo K. Mellinghoff;Maria Y. Wang;Igor Vivanco;Daphne A. Haas-Kogan

  • Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

    Rameen Beroukhim;Gad Getz;Leia Nghiemphu;Jordi Barretina

  • Intertumoral Heterogeneity within Medulloblastoma Subgroups

    Florence M.G. Cavalli;Marc Remke;Marc Remke;Marc Remke;Ladislav Rampasek;John Peacock

  • High-throughput oncogene mutation profiling in human cancer

    Roman K. Thomas;Alissa C. Baker;Ralph M. DeBiasi;Ralph M. DeBiasi;Wendy Winckler;Wendy Winckler

  • Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma.

    Timothy F. Cloughesy;Aaron Y. Mochizuki;Joey R. Orpilla;Willy Hugo

  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes

    Paul A. Northcott;Paul A. Northcott;David J.H. Shih;John Peacock;Livia Garzia

  • The whole-genome landscape of medulloblastoma subtypes

    Paul A. Northcott;Paul A. Northcott;Ivo Buchhalter;Ivo Buchhalter;A. Sorana Morrissy;Volker Hovestadt

  • Gene Expression Profiling of Gliomas Strongly Predicts Survival

    William A. Freije;F. Edmundo Castro-Vargas;Zixing Fang;Steve Horvath

  • Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target

    S. Horvath;B. Zhang;M. Carlson;K. V. Lu

  • Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma

    Tim F Cloughesy;Koji Yoshimoto;Phioanh Leia Nghiemphu;Kevin Brown

  • Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment

    Linda M. Liau;Robert M. Prins;Sylvia M. Kiertscher;Sylvia K. Odesa

  • Phase II Study of Bevacizumab Plus Temozolomide During and After Radiation Therapy for Patients With Newly Diagnosed Glioblastoma Multiforme

    Albert Lai;Anh Tran;Phioanh L. Nghiemphu;Whitney B. Pope

  • Imaging Proliferation in Brain Tumors with 18F-FLT PET: Comparison with 18F-FDG

    Wei Chen;Timothy Cloughesy;Nirav Kamdar;Nagichettiar Satyamurthy

  • Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma

    Nataliya Zhukova;Vijay Ramaswamy;Marc Remke;Elke Pfaff

  • Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.

    Albert Lai;Samir Kharbanda;Whitney B. Pope;Anh Tran

  • First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

    Linda M. Liau;Keyoumars Ashkan;David D. Tran;Jian L. Campian

  • Gene Expression Profile Correlates with T-Cell Infiltration and Relative Survival in Glioblastoma Patients Vaccinated with Dendritic Cell Immunotherapy

    Robert M Prins;Horacio Soto;Veerauo Konkankit;Sylvia K. Odesa

  • Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies

    Selvaraju Veeriah;Barry S Taylor;Shasha Meng;Fang Fang

  • Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.

    Jeffrey C Lee;Jeffrey C Lee;Igor Vivanco;Rameen Beroukhim;Rameen Beroukhim;Julie H. Y Huang

Frequent Co-Authors

Timothy F. Cloughesy
Timothy F. Cloughesy University of California, Los Angeles
Albert Lai
Albert Lai University of Washington
Paul S. Mischel
Paul S. Mischel Stanford University
Stanley F. Nelson
Stanley F. Nelson University of California, Los Angeles
Ingo K. Mellinghoff
Ingo K. Mellinghoff Memorial Sloan Kettering Cancer Center
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Rameen Beroukhim
Rameen Beroukhim Harvard University
Michael A. Vogelbaum
Michael A. Vogelbaum Cleveland Clinic
Santosh Kesari
Santosh Kesari University of California, San Diego
Michael D. Taylor
Michael D. Taylor University of Toronto

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