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Medicine

D-Index
80
Citations
20256
World Ranking
17257
National Ranking
8648

Overview

Albert Lai is affiliated with the University of Washington in the United States and has a research focus primarily in the field of Medicine. Their scholarly contributions span several subfields, including Radiology, Nuclear Medicine and Imaging, Genetics, Molecular Biology, Cancer Research, and Pulmonary and Respiratory Medicine.

Their main research topics encompass Glioma Diagnosis and Treatment, MRI in Cancer Diagnosis, Radiomics and Machine Learning in Medical Imaging, Advanced MRI Techniques and Applications, Cancer, Hypoxia, and Metabolism, Medical Imaging Techniques and Applications, and Advanced Neuroimaging Techniques and Applications.

Albert Lai has contributed extensively to scientific literature with key publications including:

  • Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition, 2021, Molecular Cell
  • Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy, 2020, iScience
  • MRI Radiomic Features to Predict IDH1 Mutation Status in Gliomas: A Machine Learning Approach using Gradient Tree Boosting, 2020, International Journal of Molecular Sciences
  • Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo, 2023, Journal of Medicinal Chemistry
  • Human IDH mutant 1p/19q co-deleted gliomas have low tumor acidity as evidenced by molecular MRI and PET: a retrospective study, 2020, Scientific Reports

Albert Lai frequently collaborates with a group of co-authors, including:

  • Timothy F. Cloughesy
  • Phioanh L. Nghiemphu
  • Benjamin M. Ellingson
  • Catalina Raymond
  • Noriko Salamon

The venues where Albert Lai has most often published are:

  • Neuro-Oncology
  • Neuro-Oncology Advances
  • Journal of Neuro-Oncology
  • Preprints.org
  • Journal of Medicinal Chemistry

Best Publications

  • Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

    Loren M. Lasko;Clarissa G. Jakob;Rohinton P. Edalji;Wei Qiu

  • Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma

    Tim F Cloughesy;Koji Yoshimoto;Phioanh Leia Nghiemphu;Kevin Brown

  • Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

    E. Robert McDonald;Antoine de Weck;Michael R. Schlabach;Eric Billy

  • A review of approaches to identifying patient phenotype cohorts using electronic health records

    Chaitanya P. Shivade;Preethi Raghavan;Eric Fosler-Lussier;Peter J. Embi

  • Phase II Study of Bevacizumab Plus Temozolomide During and After Radiation Therapy for Patients With Newly Diagnosed Glioblastoma Multiforme

    Albert Lai;Anh Tran;Phioanh L. Nghiemphu;Whitney B. Pope

  • A Randomized Trial Comparing Telemedicine Case Management with Usual Care in Older, Ethnically Diverse, Medically Underserved Patients with Diabetes Mellitus: 5 Year Results of the IDEATel Study

    Steven Shea;Ruth S. Weinstock;Ruth S. Weinstock;Jeanne A. Teresi;Jeanne A. Teresi;Walter Palmas

  • Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.

    Albert Lai;Samir Kharbanda;Whitney B. Pope;Anh Tran

  • Predicting Treatment Response of Malignant Gliomas to Bevacizumab and Irinotecan by Imaging Proliferation With [18F] Fluorothymidine Positron Emission Tomography: A Pilot Study

    Wei Chen;Sibylle Delaloye;Daniel H.S. Silverman;Cheri Geist

  • Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.

    Konstantinos J. Mavrakis;E. Robert McDonald;Michael R. Schlabach;Eric Billy

  • Recurrent glioblastoma multiforme: ADC histogram analysis predicts response to bevacizumab treatment.

    Whitney B Pope;Hyun J Kim;Jing Huo;Jeffry Alger

  • MRI in Patients With High-Grade Gliomas Treated With Bevacizumab and Chemotherapy

    W. B. Pope;A. Lai;P. Nghiemphu;P. Mischel

  • Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy

    Whitney B. Pope;Robert M. Prins;M. Albert Thomas;Rajakumar Nagarajan

  • Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial

    Thomas Sandmann;Richard Bourgon;Josep Garcia;Congfen Li

  • Predicting the efficacy of radiotherapy in individual glioblastoma patients in vivo: a mathematical modeling approach

    R Rockne;J K Rockhill;M Mrugala;A M Spence

  • Relationship between Tumor Enhancement, Edema, IDH1 Mutational Status, MGMT Promoter Methylation, and Survival in Glioblastoma

    J.A. Carrillo;A. Lai;P.L. Nghiemphu;H.J. Kim

  • Characterization of Sorting Signals in the β-Amyloid Precursor Protein Cytoplasmic Domain

    Albert Lai;Albert Lai;Sangram S. Sisodia;Ian S. Trowbridge

  • Bevacizumab and chemotherapy for recurrent glioblastoma A single-institution experience

    P. L. Nghiemphu;W. Liu;Y. Lee;T. Than

  • Prognostic Significance of Growth Kinetics in Newly Diagnosed Glioblastomas Revealed by Combining Serial Imaging with a Novel Biomathematical Model

    Christina H. Wang;Jason K. Rockhill;Maciej Mrugala;Danielle L. Peacock

  • RBP1 Recruits the mSIN3-Histone Deacetylase Complex to the Pocket of Retinoblastoma Tumor Suppressor Family Proteins Found in Limited Discrete Regions of the Nucleus at Growth Arrest

    Albert Lai;Brian K. Kennedy;David A. Barbie;Nicholas R. Bertos

  • Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability.

    Albert Lai;Emese Filka;Bruce McGibbon;Phioanh Leia Nghiemphu

Frequent Co-Authors

Timothy F. Cloughesy
Timothy F. Cloughesy University of California, Los Angeles
Linda M. Liau
Linda M. Liau University of California, Los Angeles
Paul S. Mischel
Paul S. Mischel Stanford University
Johannes Czernin
Johannes Czernin University of California, Los Angeles
Patrick Y. Wen
Patrick Y. Wen Harvard University
Michael E. Phelps
Michael E. Phelps University of California, Los Angeles
Justin Starren
Justin Starren Northwestern University
Robert Elashoff
Robert Elashoff University of California, Los Angeles
Stanley F. Nelson
Stanley F. Nelson University of California, Los Angeles

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