D-Index & Metrics Best Publications

Dale B. Wigley

Imperial College London
United Kingdom

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Molecular Biology D-index 62 Citations 14,085 131 World Ranking 1221 National Ranking 103

Research.com Recognitions

Awards & Achievements

2004 - Fellow of the Royal Society, United Kingdom

Overview

What is he best known for?

The fields of study Dale B. Wigley is best known for:

Enzyme
DNA
Gene

Dale B. Wigley performs multidisciplinary study in Gene and Protein subunit in his work. In his study, Dale B. Wigley carries out multidisciplinary Protein subunit and Active site research. Dale B. Wigley performs integrative study on Active site and Gene. His study in Structural similarity extends to Biochemistry with its themes. Structural similarity connects with themes related to Biochemistry in his study. He undertakes interdisciplinary study in the fields of Stereochemistry and Organic chemistry through his research. He conducted interdisciplinary study in his works that combined Organic chemistry and Polymer. His multidisciplinary approach integrates Polymer and Catalysis in his work. Dale B. Wigley integrates Catalysis with Enzyme in his study.

His most cited work include:

The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography. (302 citations)
Enzymatic Ketonization of 2-Hydroxymuconate: Specificity and Mechanism Investigated by the Crystal Structures of Two Isomerases (118 citations)

What are the main themes of his work throughout his whole career to date

Dale B. Wigley regularly ties together related areas like Overproduction in his Gene studies. His Genetics research extends to the thematically linked field of Overproduction. He integrates Genetics with Cell biology in his study. Dale B. Wigley performs multidisciplinary study in Cell biology and DNA in his work. He undertakes interdisciplinary study in the fields of DNA and Binding site through his works. In his works, he conducts interdisciplinary research on Binding site and Active site. Dale B. Wigley merges Active site with Enzyme kinetics in his research. Much of his study explores Biochemistry relationship to Structural similarity. His Structural similarity study frequently draws connections to other fields, such as Biochemistry.

Dale B. Wigley most often published in these fields:

Gene (100.00%)
Biochemistry (63.64%)
DNA (54.55%)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure and mechanism of helicases and nucleic acid translocases.

Martin R Singleton;Mark S Dillingham;Dale B Wigley.
Annual Review of Biochemistry (2007)

1270 Citations

Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism.

Sameer S Velankar;Panos Soultanas;Mark S Dillingham;Hosahalli S Subramanya.
Cell (1999)

885 Citations

Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

Dale B. Wigley;Gideon J. Davies;Eleanor J. Dodson;Anthony Maxwell.
Nature (1991)

657 Citations

Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides.

Martin R Singleton;Michael R Sawaya;Tom Ellenberger;Dale B Wigley.
Cell (2000)

571 Citations

Crystal structure of a DExx box DNA helicase.

Hosahalli S. Subramanya;Louise E. Bird;James A. Brannigan;Dale B. Wigley.
Nature (1996)

528 Citations

Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks

Martin R. Singleton;Mark S. Dillingham;Martin Gaudier;Stephen C. Kowalczykowski.
Nature (2004)

442 Citations

THE NATURE OF INHIBITION OF DNA GYRASE BY THE COUMARINS AND THE CYCLOTHIALIDINES REVEALED BY X-RAY CRYSTALLOGRAPHY

R. J. Lewis;O. M. P. Singh;C. V. Smith;T. Skarzynski.
The EMBO Journal (1996)

396 Citations

The third IgG-binding domain from streptococcal protein G. An analysis by X-ray crystallography of the structure alone and in a complex with Fab.

Jeremy P. Derrick;Dale B. Wigley.
Journal of Molecular Biology (1994)

392 Citations

Structural Analysis of DNA Replication Fork Reversal by RecG

Martin R. Singleton;Sarah Scaife;Dale B. Wigley.
Cell (2001)

367 Citations

Crystal Structure of an ATP-Dependent DNA Ligase from Bacteriophage T7

Hosahalli S. Subramanya;Aidan J. Doherty;Stephen R. Ashford;Dale B. Wigley.
Cell (1996)

287 Citations

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Frequent Co-Authors

External Links

Personal Website for Dale B. Wigley