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Genetics

D-Index
85
Citations
22481
World Ranking
1320
National Ranking
171

Research.com Recognitions

  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1992 - Fellow of the Royal Society, United Kingdom
  • 1984 - Fellow of the Royal Society of Edinburgh

Overview

David J. Sherratt is affiliated with the University of Oxford in the United Kingdom, specializing in the fields of Biochemistry, Genetics, and Molecular Biology. Their research portfolio spans 36 publications in these areas, with a focus on subfields such as Molecular Biology, Genetics, Ecology, Molecular Medicine, and Endocrinology.

Their work extensively covers topics including Bacterial Genetics and Biotechnology, DNA Repair Mechanisms, Bacteriophages and microbial interactions, DNA and Nucleic Acid Chemistry, Antibiotic Resistance in Bacteria, Diffusion and Search Dynamics, and Genomics and Chromatin Dynamics.

Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Current Genetics
  • Proceedings of the National Academy of Sciences
  • Antibiotics

Key recent papers include:

  • "Organization of the Escherichia coli Chromosome by a MukBEF Axial Core," 2020, Molecular Cell
  • "Transient non-specific DNA binding dominates the target search of bacterial DNA-binding proteins," 2021, Molecular Cell
  • "SMC complexes organize the bacterial chromosome by lengthwise compaction," 2020, Current Genetics
  • "Nonrandom segregation of sister chromosomes by Escherichia coli MukBEF," 2021, Proceedings of the National Academy of Sciences
  • "Functional Analysis of the Acinetobacter baumannii XerC and XerD Site-Specific Recombinases: Potential Role in Dissemination of Resistance Genes," 2020, Antibiotics

Frequent co-authors collaborating with Sherratt include:

  • Jarno Mäkelä
  • Stephan Uphoff
  • Mathew Stracy
  • Rachel Baker
  • Gemma Fisher

Throughout their career, Sherratt has been recognized by multiple fellowships: Fellow of the Royal Society of Edinburgh since 1984, Fellow of the Royal Society, United Kingdom since 1992, and Fellow of the American Association for the Advancement of Science (AAAS) since 2005.

Best Publications

  • The importance of repairing stalled replication forks

    Michael M. Cox;Myron F. Goodman;Kenneth N. Kreuzer;David J. Sherratt

  • Multimerization of high copy number plasmids causes instability: Cole 1 encodes a determinant essential for plasmid monomerization and stability

    David K. Summers;David J. Sherratt

  • Catalysis by site-specific recombinases.

    W. Marshall Stark;Martin R. Boocock;David J. Sherratt

  • Spatial and temporal organization of replicating Escherichia coli chromosomes.

    Ivy F. Lau;Sergio R. Filipe;Britta Søballe;Ole-Andreas Økstad

  • Stoichiometry and architecture of active DNA replication machinery in Escherichia coli.

    Rodrigo Reyes-Lamothe;David J. Sherratt;Mark C. Leake

  • Two related recombinases are required for site-specific recombination at dif and cer in E. coli K12.

    Garry Blakely;Gerhard May;Richard McCulloch;Lidia K. Arciszewska

  • FtsK Is a DNA Motor Protein that Activates Chromosome Dimer Resolution by Switching the Catalytic State of the XerC and XerD Recombinases

    Laurent Aussel;François Xavier Barre;Mira Aroyo;Andrzej Stasiak

  • Independent positioning and action of Escherichia coli replisomes in live cells.

    Rodrigo Reyes-Lamothe;Christophe Possoz;Olessia Danilova;David J. Sherratt

  • Double-Stranded DNA Translocation: Structure and Mechanism of Hexameric Ftsk

    Thomas H. Massey;Christopher P. Mercogliano;James Yates;David J. Sherratt

  • Bacterial Chromosome Dynamics

    David J. Sherratt

  • Site-specific recombination by Tn3 resolvase: Topological changes in the forward and reverse reactions

    W.Marshall Stark;David J. Sherratt;Martin R. Boocock

  • In Vivo Architecture and Action of Bacterial Structural Maintenance of Chromosome Proteins

    Anjana Badrinarayanan;Rodrigo Reyes-Lamothe;Stephan Uphoff;Mark C. Leake

  • Crystal structure of the site-specific recombinase, XerD

    Hosahalli S. Subramanya;Lidia K. Arciszewska;Rachel A. Baker;Louise E. Bird

  • Escherichia coli XerC recombinase is required for chromosomal segregation at cell division.

    G. Blakely;S. Colloms;Gerhard May;M. Burke

  • The two Escherichia coli chromosome arms locate to separate cell halves

    Xindan Wang;Xun Liu;Christophe Possoz;David J. Sherratt

  • xerB, an Escherichia coli gene required for plasmid ColE1 site-specific recombination, is identical to pepA, encoding aminopeptidase A, a protein with substantial similarity to bovine lens leucine aminopeptidase.

    C J Stirling;S D Colloms;J F Collins;G Szatmari

  • MapZ marks the division sites and positions FtsZ rings in Streptococcus pneumoniae

    Aurore Fleurie;Christian Lesterlin;Sylvie Manuse;Chao Zhao;Chao Zhao

  • A streptavidin variant with slower biotin dissociation and increased mechanostability.

    Claire E Chivers;Estelle Crozat;Calvin Chu;Vincent T Moy

  • Chromosome Replication and Segregation in Bacteria

    Rodrigo Reyes-Lamothe;Emilien Nicolas;David J. Sherratt

  • Sequence-directed DNA translocation by purified FtsK.

    Paul J. Pease;Oren Levy;Gregory J. Cost;Jeff Gore

Frequent Co-Authors

Marcelo E. Tolmasky
Marcelo E. Tolmasky California State University, Fullerton
Jan Löwe
Jan Löwe MRC Laboratory of Molecular Biology
Eric C. Greene
Eric C. Greene Columbia University
Anthony Maxwell
Anthony Maxwell John Innes Centre
Cees Dekker
Cees Dekker Delft University of Technology
Carol V. Robinson
Carol V. Robinson University of Oxford
Nick R. Leslie
Nick R. Leslie Heriot-Watt University
Dale B. Wigley
Dale B. Wigley Imperial College London
Albert Jeltsch
Albert Jeltsch University of Stuttgart
Kenn Gerdes
Kenn Gerdes University of Copenhagen

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