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Immunology

D-Index
76
Citations
21918
World Ranking
1907
National Ranking
930

Overview

David A. Lawrence is affiliated with the New York State Department of Health in the United States. Their research spans multiple disciplines within medicine and biochemistry, genetics, and molecular biology.

Their recent papers cover a range of topics in environmental health, cancer research, cellular stress responses, and immunology. Notable publications include:

  • Exposure, health effects, sensing, and remediation of the emerging PFAS contaminants - Scientific challenges and potential research directions (2021) in The Science of The Total Environment
  • IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment (2020) in Cancer Research
  • Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α (2021) in Nature Communications
  • Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation (2022) in The Journal of Cell Biology
  • Health disparities: Intracellular consequences of social determinants of health (2021) in Toxicology and Applied Pharmacology

Frequent co-authors collaborating with Lawrence include:

  • Scot A. Marsters
  • Avi Ashkenazi
  • Mohammad Nizam Uddin
  • Kevin Manley
  • Zora Modrušan

Their work is commonly published in venues such as:

  • Journal of Biochemical and Molecular Toxicology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Toxicology and Environmental Health Part B
  • Brain Behavior & Immunity - Health

Lawrence's research integrates the following major fields of study:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields in which they have significant publication activity include:

  • Molecular Biology
  • Immunology
  • Health, Toxicology and Mutagenesis
  • Genetics
  • Epidemiology

The main topics explored throughout their work involve:

  • Autism Spectrum Disorder Research
  • Endoplasmic Reticulum Stress and Disease
  • Genetics and Neurodevelopmental Disorders
  • Immune Cell Function and Interaction
  • Per- and polyfluoroalkyl substances research
  • Air Quality and Health Impacts
  • Gut microbiota and health

Best Publications

  • Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

    Robert M. Pitti;Scot A. Marsters;David A. Lawrence;Margaret Roy

  • Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

    David Lawrence;Zahra Shahrokh;Scot Marsters;Kirsten Achilles

  • Deterministic hydrodynamics: Taking blood apart

    John A. Davis;David W. Inglis;Keith J. Morton;David A. Lawrence

  • Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects.

    Joel M. Kremer;David A. Lawrence;William Jubiz;Ralph Digiacomo

  • Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL

    Klaus W Wagner;Elizabeth A Punnoose;Thomas Januario;David A Lawrence

  • Effects of high-dose fish oil on rheumatoid arthritis after stopping nonsteroidal antiinflammatory drugs. Clinical and immune correlates.

    Joel M. Kremer;David A. Lawrence;Gayle F. Petrillo;Laura L. Litts

  • An Fcγ Receptor-Dependent Mechanism Drives Antibody-Mediated Target-Receptor Signaling in Cancer Cells

    Nicholas S. Wilson;Becky Yang;Annie Yang;Stefanie Loeser

  • Immunoglobulins cytophilic for human lymphocytes, monocytes, and neutrophils.

    D A Lawrence;W O Weigle;H L Spiegelberg

  • TWEAK Attenuates the Transition from Innate to Adaptive Immunity

    Heather Maecker;Eugene Varfolomeev;Frank Kischkel;David Lawrence

  • Lead differentially modifies cytokine production in vitro and in vivo.

    Yong Heo;Patrick J. Parsons;Patrick J. Parsons;David A. Lawrence;David A. Lawrence

  • Induction of IL-33 expression and activity in central nervous system glia

    Chad A. Hudson;George P. Christophi;Ross C. Gruber;Joel R. Wilmore

  • APRIL-Deficient Mice Have Normal Immune System Development

    Eugene Varfolomeev;Frank Kischkel;Flavius Martin;Dhaya Seshasayee

  • Aberrant Immune Responses in a Mouse with Behavioral Disorders

    Yong Heo;Yubin Zhang;Yubin Zhang;Donghong Gao;Veronica M. Miller

  • Heavy metal modulation of lymphocyte activities

    David A. Lawrence

  • CD4+CD25high T cell numbers are enriched in the peripheral blood of patients with rheumatoid arthritis.

    Guang Ming Han;Nancy J. O’Neil-Andersen;Robert B. Zurier;David A. Lawrence

  • Immunomodulation by metals

    David A Lawrence;Michael J McCabe

  • Cautionary insights on knockout mouse studies: the gene or not the gene?

    Amy F. Eisener-Dorman;David A. Lawrence;David A. Lawrence;Valerie J. Bolivar;Valerie J. Bolivar

  • Regular ArticleLead Differentially Modifies Cytokine Productionin Vitroandin Vivo

    Yong Heo;Patrick J. Parsons;David A. Lawrence

  • Metal-induced modulation of nitric oxide production in vitro by murine macrophages : Lead, nickel, and cobalt utilize different mechanisms

    L Tian;D A Lawrence

  • Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism.

    Nikolay M. Filipov;Richard F. Seegal;David A. Lawrence

  • Differential Effects of Lead and cAMP on Development and Activities of Th1- and Th2-Lymphocytes

    Yong Heo;William T. Lee;David A. Lawrence

  • Surface thiols of human lymphocytes and their changes after in vitro and in vivo activation.

    D A Lawrence;R Song;P Weber

  • Lead, a major environmental pollutant, is immunomodulatory by its differential effects on CD4+ T cell subsets

    Michael J. McCabe;David A. Lawrence

Frequent Co-Authors

David O. Carpenter
David O. Carpenter University at Albany, State University of New York
Germaine M. Buck Louis
Germaine M. Buck Louis George Mason University
Joel M. Kremer
Joel M. Kremer Albany Medical Center Hospital
David H. Overstreet
David H. Overstreet University of North Carolina at Chapel Hill
Brent E. Palmer
Brent E. Palmer University of Colorado Denver
Stephen E. Gilman
Stephen E. Gilman Eunice Kennedy Shriver National Institute of Child Health and Human Development
Xinxin Ding
Xinxin Ding University of Arizona
Kurunthachalam Kannan
Kurunthachalam Kannan University at Albany, State University of New York
James C. Sturm
James C. Sturm Princeton University
Stephen Y. Chou
Stephen Y. Chou Princeton University

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