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D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
21762
World Ranking
3731
National Ranking
279

Simon J. R. Heales publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Simon J. R. Heales sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 268 publications — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Simon J. R. Heales D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Simon J. R. Heales sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 82 D-Index — 82nd percentile

82% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Simon J. R. Heales is affiliated with University College London in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with particular contributions across several subfields including Molecular Biology, Physiology, Clinical Biochemistry, Genetics, and Biochemistry.

Their published work covers a range of specialized topics, such as:

  • Metabolism and Genetic Disorders
  • Mitochondrial Function and Pathology
  • Diet and metabolism studies
  • Lysosomal Storage Disorders Research
  • Amino Acid Enzymes and Metabolism
  • Coenzyme Q10 studies and effects
  • Genomics and Rare Diseases

Heales has contributed to multiple research papers, including recent notable publications such as:

  • Consensus guideline for the diagnosis and treatment of tetrahydrobiopterin (BH4) deficiencies, 2020, Orphanet Journal of Rare Diseases
  • Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's, 2022, Acta Neuropathologica Communications
  • Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism, 2021, Science Translational Medicine
  • Classic ketogenic diet versus further antiseizure medicine in infants with drug-resistant epilepsy (KIWE): a UK, multicentre, open-label, randomised clinical trial, 2023, The Lancet Neurology
  • The Effect of Cellular Coenzyme Q10 Deficiency on Lysosomal Acidification, 2020, Journal of Clinical Medicine

Frequently publishing in journals such as the International Journal of Neonatal Screening, Molecular Genetics and Metabolism, Orphanet Journal of Rare Diseases, Science Translational Medicine, and Journal of Clinical Medicine, Heales has established a presence in venues focused on molecular and clinical aspects of rare diseases and metabolic disorders.

Collaborative efforts have included repeated partnerships with several co-authors, who have frequently appeared in their publications. These collaborators are:

  • Simon Eaton
  • Simon Pope
  • Alberto Burlina
  • Wendy Heywood
  • Michael Orford

The scope of Heales' research reflects a multidisciplinary approach combining clinical and molecular insights into rare genetic disorders, mitochondrial dysfunction, and metabolic pathways, including therapeutic strategies and diagnostic guidelines.

Best Publications

  • Association between mitochondrial dysfunction and severity and outcome of septic shock

    David Brealey;Michael Brand;Iain Hargreaves;Simon Heales

  • Nitric oxide-mediated mitochondrial damage in the brain: mechanisms and implications for neurodegenerative diseases

    Juan P. Bolaños;Angeles Almeida;Victoria Stewart;Stephan Peuchen

  • Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture.

    Juan P. Bolaños;Simon J. R. Heales;John M. Land;John B. Clark

  • Nitric oxide, mitochondria and neurological disease.

    Simon J.R. Heales;Juan P. Bolaños;Victoria C. Stewart;Paul S. Brookes

  • Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes.

    J. P. Bolaños;S. Peuchen;S. J. R. Heales;J. M. Land

  • Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders.

    Katrin Augustin;Aziza Khabbush;Sophie Williams;Simon Eaton

  • PINK1 protein in normal human brain and Parkinson's disease

    S Gandhi;M M K Muqit;L Stanyer;D G Healy

  • The monoamine neurotransmitter disorders: an expanding range of neurological syndromes

    Manju A Kurian;Manju A Kurian;Paul Gissen;Paul Gissen;Martin Smith;Simon Jr Heales

  • PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons.

    Alison Wood-Kaczmar;Sonia Gandhi;Zhi Yao;Andrey S. Y. Abramov

  • Neonatal epileptic encephalopathy caused by mutations in the PNPO gene encoding pyridox(am)ine 5'-phosphate oxidase

    Philippa B. Mills;Robert A.H. Surtees;Michael P. Champion;Clare E. Beesley

  • Nitric oxide-mediated mitochondrial damage: A potential neuroprotective role for glutathione

    Juan P. Bolaños;Simon J.R. Heales;Stefan Peuchen;Jane E. Barker

  • Monoamine neurotransmitter disorders—clinical advances and future perspectives

    Joanne Ng;Apostolos Papandreou;Simon J. Heales;Manju A. Kurian

  • Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function.

    Malcolm J. Jackson;Sergio Papa;Juan Bolaños;Richard Bruckdorfer

  • Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration.

    Guy C. Brown;Juan P. Bolaños;Simon J.R. Heales;John B. Clark

  • Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia.

    Manju A. Kurian;Juan Zhen;Shu-Yuan Cheng;Yan Li

  • Clinical and biochemical features of aromatic L-amino acid decarboxylase deficiency.

    L. Brun;L. H. Ngu;W. T. Keng;G. S. Ch'ng

  • Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice

    Sergio Rodriguez-Cuenca;Helena M. Cochemé;Helena M. Cochemé;Angela Logan;Irina Abakumova

  • Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study.

    Manju A. Kurian;Manju A. Kurian;Yan Li;Juan Zhen;Esther Meyer

  • Adaptation of the Nitrate Reductase and Griess Reaction Methods for the Measurement of Serum Nitrate plus Nitrite Levels

    G Giovannoni;J M Land;G Keir;E J Thompson

  • Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease

    Laura Dunn;George F. G. Allen;Adamantios Mamais;Helen Ling

Frequent Co-Authors

John M. Land
John M. Land University College London
John B. Clark
John B. Clark University College London
Iain P. Hargreaves
Iain P. Hargreaves Liverpool John Moores University
Manju A. Kurian
Manju A. Kurian University College London
Juan P. Bolaños
Juan P. Bolaños University of Salamanca
Paul Gissen
Paul Gissen University College London
Peter E. Clayton
Peter E. Clayton University of Manchester
Nicholas W. Wood
Nicholas W. Wood University College London
Shamima Rahman
Shamima Rahman University College London
Kailash P. Bhatia
Kailash P. Bhatia University College London

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