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Genetics

D-Index
63
Citations
16627
World Ranking
2873
National Ranking
134

Overview

Didier Mazel is affiliated with Université Paris Cité in France and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology, with 149 publications. Their research spans several subfields including Endocrinology, Molecular Biology, Molecular Medicine, Genetics, and Ecology.

Their work addresses a variety of main topics such as:

  • Vibrio bacteria research studies
  • Antibiotic Resistance in Bacteria
  • Bacterial Genetics and Biotechnology
  • Escherichia coli research studies
  • Bacteriophages and microbial interactions
  • RNA and protein synthesis mechanisms
  • CRISPR and Genetic Engineering

Didier Mazel's frequent collaborators include Zeynep Baharoglu, Céline Loot, Baptiste Darracq, Julia Bos, and Evelyne Krin. Together, they have published numerous works advancing various aspects of bacterial genetics and antibiotic resistance.

Their research has been published in a range of scientific venues, with notable numbers in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Advances
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Nucleic Acids Research
  • mBio

Recent significant publications include:

  • "Real-time tracking of bacterial membrane vesicles reveals enhanced membrane traffic upon antibiotic exposure" (2021, Science Advances)
  • "Aminoglycoside uptake, stress, and potentiation in Gram-negative bacteria: new therapies with old molecules" (2023, Microbiology and Molecular Biology Reviews)
  • "Nonessential tRNA and rRNA modifications impact the bacterial response to sub-MIC antibiotic stress" (2022, microLife)
  • "Sleeping ribosomes: Bacterial signaling triggers RaiA mediated persistence to aminoglycosides" (2021, iScience)
  • "Metagenomic strategies identify diverse integron-integrase and antibiotic resistance genes in the Antarctic environment" (2021, MicrobiologyOpen)

Best Publications

  • Integrons: agents of bacterial evolution

    Didier Mazel

  • A Distinctive Class of Integron in the Vibrio cholerae Genome

    Didier Mazel;Broderick Dychinco;Vera A. Webb;Julian Davies

  • The SOS Response Controls Integron Recombination

    Émilie Guerin;Guillaume Cambray;Neus Sanchez-Alberola;Susana Campoy

  • Antibiotic resistance in microbes

    D. Mazel;J. Davies

  • Silent Mischief: Bacteriophage Mu Insertions Contaminate Products of Escherichia coli Random Mutagenesis Performed Using Suicidal Transposon Delivery Plasmids Mobilized by Broad-Host-Range RP4 Conjugative Machinery

    Lionel Ferrières;Lionel Ferrières;Gaëlle Hémery;Gaëlle Hémery;Toan Nham;Toan Nham;Anne-Marie Guérout;Anne-Marie Guérout

  • Molecular analysis of antibiotic resistance gene clusters in vibrio cholerae O139 and O1 SXT constins.

    Bianca Hochhut;Yasmin Lotfi;Didier Mazel;Shah M. Faruque

  • Antibiotic Resistance in the ECOR Collection: Integrons and Identification of a Novel aad Gene

    Didier Mazel;Broderick Dychinco;Vera A. Webb;Julian Davies

  • A new family of mobilizable suicide plasmids based on broad host range R388 plasmid (IncW) and RP4 plasmid (IncPalpha) conjugative machineries and their cognate Escherichia coli host strains.

    Gaëlle Demarre;Anne-Marie Guérout;Chiho Matsumoto-Mashimo;Dean A. Rowe-Magnus

  • SOS, the formidable strategy of bacteria against aggressions.

    Zeynep Baharoglu;Didier Mazel

  • β-lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity

    A. Gutierrez;L. Laureti;S. Crussard;H. Abida

  • Bacterial resistance evolution by recruitment of super‐integron gene cassettes

    Dean A. Rowe-Magnus;Anne-Marie Guerout;Didier Mazel

  • The role of integrons in antibiotic resistance gene capture.

    Dean A. Rowe-Magnus;Dean A. Rowe-Magnus;Didier Mazel

  • The evolutionary history of chromosomal super-integrons provides an ancestry for multiresistant integrons

    Dean A. Rowe-Magnus;Anne-Marie Guerout;Pascaline Ploncard;Broderick Dychinco

  • Construction of a Vibrio splendidus mutant lacking the metalloprotease gene vsm by use of a novel counterselectable suicide vector.

    Frédérique Le Roux;Frédérique Le Roux;Johan Binesse;Denis Saulnier;Didier Mazel

  • Genetic characterization of polypeptide deformylase, a distinctive enzyme of eubacterial translation.

    Mazel D;Pochet S;Marlière P

  • Conjugative DNA Transfer Induces the Bacterial SOS Response and Promotes Antibiotic Resistance Development through Integron Activation

    Zeynep Baharoglu;David Bikard;David Bikard;Didier Mazel;Didier Mazel

  • Vibrio cholerae Triggers SOS and Mutagenesis in Response to a Wide Range of Antibiotics: a Route towards Multiresistance

    Zeynep Baharoglu;Zeynep Baharoglu;Didier Mazel;Didier Mazel

  • Comparative Analysis of Superintegrons: Engineering Extensive Genetic Diversity in the Vibrionaceae

    Dean A. Rowe-Magnus;Anne-Marie Guerout;Latefa Biskri;Philippe Bouige

  • Integrons: natural tools for bacterial genome evolution

    Dean A Rowe-Magnus;Didier Mazel

  • Folded DNA in Action: Hairpin Formation and Biological Functions in Prokaryotes

    David Bikard;David Bikard;Céline Loot;Céline Loot;Zeynep Baharoglu;Zeynep Baharoglu;Didier Mazel;Didier Mazel

Frequent Co-Authors

Frédérique Le Roux
Frédérique Le Roux French Research Institute for Exploitation of the Sea
Julian Davies
Julian Davies University of British Columbia
Eduardo P. C. Rocha
Eduardo P. C. Rocha Institut Pasteur
Claudine Médigue
Claudine Médigue University of Paris-Saclay
Christiane Bouchier
Christiane Bouchier Institut Pasteur
Jean-Marc Ghigo
Jean-Marc Ghigo Institut Pasteur
Donald A. Bryant
Donald A. Bryant Pennsylvania State University
Jean-Yves Coppée
Jean-Yves Coppée Institut Pasteur
Matthew K. Waldor
Matthew K. Waldor Harvard Medical School

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