World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
95
Citations
27219
World Ranking
909
National Ranking
452

Research.com Recognitions

  • 2019 - Member of the National Academy of Sciences

Overview

Edward H. Egelman is affiliated with the University of Virginia in the United States and works primarily in the field of Biochemistry, Genetics and Molecular Biology. Their research spans various subfields, including Molecular Biology, Ecology, Biomaterials, Genetics, and Structural Biology.

Their work covers several main topics, such as:

  • Bacteriophages and microbial interactions
  • Supramolecular Self-Assembly in Materials
  • Bacterial Genetics and Biotechnology
  • Advanced Electron Microscopy Techniques and Applications
  • Genomics and Phylogenetic Studies
  • Chemical Synthesis and Analysis
  • Microbial Community Ecology and Physiology

Frequent co-authors in their collaborations include Fengbin Wang, Mark A. B. Kreutzberger, Mart Krupovìč, Ravi R. Sonani, and Virginija Cvirkaitė-Krupovič.

Edward H. Egelman's publications often appear in specialized and high-impact venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Biophysical Journal
  • Nature Communications
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature

Notable recent papers include:

  • "Cryo-EM structure of an extracellular Geobacter OmcE cytochrome filament reveals tetrahaem packing," 2022, Nature Microbiology
  • "Mating pair stabilization mediates bacterial conjugation species specificity," 2022, Nature Microbiology
  • "Cryo-EM of Helical Polymers," 2022, Chemical Reviews
  • "Artificial Intracellular Filaments," 2020, Cell Reports Physical Science
  • "Extracellular cytochrome nanowires appear to be ubiquitous in prokaryotes," 2023, Cell

Edward H. Egelman was recognized as a Member of the National Academy of Sciences in 2019.

Best Publications

  • Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

    Alvin Lu;Venkat Giri Magupalli;Venkat Giri Magupalli;Jianbin Ruan;Jianbin Ruan;Qian Yin;Qian Yin

  • Similarity of the yeast RAD51 filament to the bacterial RecA filament

    Tomoko Ogawa;Xiong Yu;Akira Shinohara;Edward H. Egelman

  • Structural Basis of Membrane Invagination by F-BAR Domains

    Adam Frost;Rushika Perera;Aurélien Roux;Krasimir Spasov

  • A robust algorithm for the reconstruction of helical filaments using single-particle methods.

    Edward H. Egelman

  • Type IV Pilus Structure by Cryo-Electron Microscopy and Crystallography: Implications for Pilus Assembly and Functions

    Lisa Craig;Niels Volkmann;Andrew S. Arvai;Michael E. Pique

  • Structure of Microbial Nanowires Reveals Stacked Hemes that Transport Electrons over Micrometers.

    Fengbin Wang;Yangqi Gu;J. Patrick O’Brien;Sophia M. Yi

  • F-actin is a helix with a random variable twist

    E H Egelman;N Francis;D J DeRosier

  • Atomic-accuracy models from 4.5-A cryo-electron microscopy data with density-guided iterative local refinement

    Frank DiMaio;Yifan Song;Xueming Li;Matthias J Brunner

  • Novel pro- and anti-recombination activities of the Bloom’s syndrome helicase

    Dmitry V. Bugreev;Xiong Yu;Edward H. Egelman;Alexander V. Mazin

  • The twist, writhe and overall shape of supercoiled DNA change during counterion-induced transition from a loosely to a tightly interwound superhelix. Possible implications for DNA structure in vivo.

    Jan Bednar;Patrick Furrer;Andrzej Stasiak;Jacques Dubochet

  • Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases.

    Edward H. Egelman;Xiong Yu;Robert Wild;Manju M. Hingorani

  • Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.

    Fumiko Esashi;Vitold E Galkin;Xiong Yu;Edward H Egelman

  • Domain structure and dynamics in the helical filaments formed by RecA and Rad51 on DNA

    Xiong Yu;Steven A. Jacobs;Stephen C. West;Tomoko Ogawa

  • Actin Depolymerizing Factor Stabilizes an Existing State of F-Actin and Can Change the Tilt of F-Actin Subunits

    Vitold E. Galkin;Albina Orlova;Natalya Lukoyanova;Willy Wriggers

  • Structure of helical RecA-DNA complexes. Complexes formed in the presence of ATP-gamma-S or ATP.

    Edward H. Egelman;Andrzej Stasiak

  • The human Rad52 protein exists as a heptameric ring

    Alicja Z. Stasiak;Eric Larquet;Andrzej Stasiak;Shirley Müller

  • Remodeling of actin filaments by ADF/cofilin proteins.

    Vitold E. Galkin;Albina Orlova;Dmitri S. Kudryashov;Alexander Solodukhin

  • The iterative helical real space reconstruction method: surmounting the problems posed by real polymers.

    Edward H. Egelman

  • A conformational change in the actin subunit can change the flexibility of the actin filament.

    A. Orlova;E.H. Egelman

  • Structure of the Type VI Secretion System Contractile Sheath

    Mikhail Kudryashev;Ray Yu Ruei Wang;Maximilian Brackmann;Sebastian Scherer

Frequent Co-Authors

Xiong Yu
Xiong Yu University of Virginia
David Prangishvili
David Prangishvili Institut Pasteur
Mart Krupovic
Mart Krupovic Université Paris Cité
Andrzej Stasiak
Andrzej Stasiak University of Lausanne
Frank DiMaio
Frank DiMaio University of Washington
Emil Reisler
Emil Reisler University of California, Los Angeles
Stephen C. West
Stephen C. West The Francis Crick Institute
Hao Wu
Hao Wu Harvard University
Michael Nilges
Michael Nilges Université Paris Cité
David J. DeRosier
David J. DeRosier Brandeis University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Genetics can lead to a wide range of healthcare and administrative roles. For students considering alternative or complementary pathways, there are several online degree options that offer flexibility and affordability.

For those interested in the administrative side of health sciences, pursuing a health administration degree online can open doors to management roles in hospitals, clinics, and health agencies. If affordability is a top concern, the cheapest online healthcare administration degree programs provide quality education without overwhelming tuition costs.

Students who prefer working directly with patients might consider enrolling in easy to get into nursing programs, which offer a streamlined route into nursing careers with flexible admissions requirements. Alternatively, the cheapest medical billing and coding online courses are ideal for those who want to quickly enter the workforce in vital support roles.

Each pathway supports entry into the dynamic healthcare industry, complementing a foundation in Genetics with skills critical for today’s healthcare landscape.

Best Scientists Citing Edward H. Egelman

Trending Scientists

Recently Published Articles