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Biology and Biochemistry

D-Index
63
Citations
13085
World Ranking
10295
National Ranking
4486

Overview

Roger Craig is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on cardiology, molecular biology, and related subfields.

The scientist's work concentrates on several topics within cardiovascular and muscle physiology. These include:

  • Cardiomyopathy and Myosin Studies
  • Muscle Physiology and Disorders
  • Cardiovascular Effects of Exercise
  • Genetic Neurodegenerative Diseases
  • Nuclear Structure and Function
  • Physiological and Biochemical Adaptations
  • Force Microscopy Techniques and Applications

Their recent publications reveal an emphasis on molecular mechanisms related to myosin and muscle contraction. Among the notable papers are:

  • "Cryo-EM structure of the human cardiac myosin filament" (2023, Nature)
  • "Structural basis of the super- and hyper-relaxed states of myosin II" (2021, The Journal of General Physiology)
  • "Cryo-EM structure of the inhibited (10S) form of myosin II" (2020, Nature)
  • "The myosin interacting-heads motif present in live tarantula muscle explains tetanic and posttetanic phosphorylation mechanisms" (2020, Proceedings of the National Academy of Sciences)
  • "Fast skeletal myosin-binding protein-C regulates fast skeletal muscle contraction" (2021, Proceedings of the National Academy of Sciences)

Roger Craig frequently collaborates with other researchers working in related fields. Frequent co-authors include:

  • Raúl Padrón
  • Debabrata Dutta
  • Kyoung Hwan Lee
  • Weikang Ma
  • Thomas C. Irving

The majority of their research is published in a range of scientific journals with multiple appearances in the following venues:

  • Biophysical Journal
  • The Journal of General Physiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Proceedings of the National Academy of Sciences

Best Publications

  • Steric-model for activation of muscle thin filaments

    Peter Vibert;Roger Craig;William Lehman

  • Light-chain phosphorylation controls the conformation of vertebrate non-muscle and smooth muscle myosin molecules.

    Roger Craig;Roger Craig;Robin Smith;John Kendrick-Jones

  • Ca 2+ -induced tropomyosin movement in Limulus thin filaments revealed by three-dimensional reconstruction

    William Lehman;Roger Craig;Peter Vibert

  • The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2.

    Tao Yang;K. M. Kozopas;R. W. Craig

  • Atomic model of a myosin filament in the relaxed state

    John L. Woodhead;Fa-Qing Zhao;Roger W. Craig;Edward H. Egelman

  • Mcl-1, a Member of the Bcl-2 Family, Delays Apoptosis Induced by c-Myc Overexpression in Chinese Hamster Ovary Cells

    J. E. Reynolds;Tao Yang;Liping Qian;J. D. Jenkinson

  • The Location of C-Protein in Rabbit Skeletal Muscle

    R Craig;G Offer

  • Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments.

    William Lehman;Victoria Hatch;Vicci Korman;Michael Rosol

  • Three-dimensional structure of vertebrate cardiac muscle myosin filaments

    Maria E. Zoghbi;John L. Woodhead;Richard L. Moss;Roger W. Craig

  • Structure and function of myosin filaments.

    Roger W. Craig;John L. Woodhead

  • The ultrastructural location of C-protein, X-protein and H-protein in rabbit muscle.

    Pauline Bennett;Roger Craig;Roger Starr;Gerald Offer

  • Steric-blocking by tropomyosin visualized in relaxed vertebrate muscle thin filaments.

    William Lehman;Peter Vibert;Pedro Uman;Roger Craig

  • Head-head and head-tail interaction: A general mechanism for switching off myosin II activity in cells

    HyunSuk Jung;Satoshi Komatsu;Mitsuo Ikebe;Roger W. Craig

  • Structural basis for the regulation of muscle contraction by troponin and tropomyosin.

    Agnieszka Galinska-Rakoczy;Patti Engel;Chen Xu;HyunSuk Jung

  • Direct visualization of myosin-binding protein C bridging myosin and actin filaments in intact muscle

    Pradeep K. Luther;Hanspeter Winkler;Kenneth Taylor;Maria E. Zoghbi;Maria E. Zoghbi

  • Assembly of smooth muscle myosin into side-polar filaments

    Roger Craig;Joseph Megerman

  • Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism

    Ji Young Mun;Michael J. Previs;Hope Y. Yu;James Gulick

  • A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscle.

    Katrina J. V. Poole;Michael Lorenz;Gwyndaf Evans;Gerd Rosenbaum

  • Tropomyosin Position on F-Actin Revealed by EM Reconstruction and Computational Chemistry

    Xiachuan Edward Li;Xiachuan Edward Li;Larry S. Tobacman;Ji Young Mun;Roger W. Craig

  • Electron microscopy of thin filaments decorated with a Ca2+-regulated myosin.

    Roger Craig;Andrew G. Szent-Györgyi;Lorena Beese;Paula Flicker

Frequent Co-Authors

William Lehman
William Lehman Boston University
Mitsuo Ikebe
Mitsuo Ikebe University of Massachusetts Chan Medical School
Jeffrey Robbins
Jeffrey Robbins Cincinnati Children's Hospital Medical Center
David M. Warshaw
David M. Warshaw University of Vermont
Jennifer E. Van Eyk
Jennifer E. Van Eyk Cedars-Sinai Medical Center
Pieter P. de Tombe
Pieter P. de Tombe University of Illinois at Chicago
Richard L. Moss
Richard L. Moss University of Wisconsin–Madison
Jun Liu
Jun Liu Yale University
Edward D. Korn
Edward D. Korn National Institutes of Health
John Kendrick-Jones
John Kendrick-Jones MRC Laboratory of Molecular Biology

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