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D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
15351
World Ranking
5744
National Ranking
2717

Overview

Mitsuo Ikebe is affiliated with the University of Massachusetts Chan Medical School in the United States and has a research profile primarily focused on Medicine and Biochemistry, Genetics, and Molecular Biology. Their recent work demonstrates significant engagement with pulmonary and respiratory medicine, molecular biology, cell biology, cardiology, cardiovascular medicine, and surgery.

The scientist's research contributions cover diverse areas, including occupational and environmental lung diseases, interstitial lung diseases and idiopathic pulmonary fibrosis, pleural and pulmonary diseases, microtubule and mitosis dynamics, cardiomyopathy and myosin studies, genetic neurodegenerative diseases, and nuclear structure and function.

Prominent publication venues where Mitsuo Ikebe has frequently contributed include the American Journal of Respiratory Cell and Molecular Biology, American Journal of Physiology-Lung Cellular and Molecular Physiology, Scientific Reports, International Journal of Molecular Sciences, and Biophysical Journal.

  • American Journal of Respiratory Cell and Molecular Biology
  • American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Scientific Reports
  • International Journal of Molecular Sciences
  • Biophysical Journal

Their collaboration network features several frequent co-authors with whom they have jointly published multiple times. These include Torry A. Tucker, Steven Idell, Osamu Satō, Ann Jeffers, and Tsuyoshi Sakai.

  • Torry A. Tucker
  • Steven Idell
  • Osamu Satō
  • Ann Jeffers
  • Tsuyoshi Sakai

Mitsuo Ikebe's recent papers highlight a broad range of topics related to cellular mechanisms, myosin function, lung pathology, and infectious disease treatment models. Selected recent publications include the following:

  • "Cryo-EM structure of the inhibited (10S) form of myosin II" (2020), published in Nature
  • "PD-L1 mediates lung fibroblast to myofibroblast transition through Smad3 and β-catenin signaling pathways" (2022), published in Scientific Reports
  • "Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice" (2024), published in Communications Biology
  • "Mitochondria-associated myosin 19 processively transports mitochondria on actin tracks in living cells" (2022), published in Journal of Biological Chemistry
  • "DOCK2 Promotes Pleural Fibrosis by Modulating Mesothelial to Mesenchymal Transition" (2021), published in American Journal of Respiratory Cell and Molecular Biology

Best Publications

  • Myosin Vb Mobilizes Recycling Endosomes and AMPA Receptors for Postsynaptic Plasticity

    Zhiping Wang;Jeffrey G. Edwards;Nathan Riley;D. William Provance

  • The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella

    Karl-Ferdinand Lechtreck;Eric C. Johnson;Tsuyoshi Sakai;Deborah A. Cochran

  • Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase

    Mutsuki Amano;Kazuyasu Chihara;Nao Nakamura;Yuko Fukata

  • Myosin light chain phosphatase activities and the effects of phosphatase inhibitors in tonic and phasic smooth muscle.

    Ming Cui Gong;P. Cohen;T. Kitazawa;M. Ikebe

  • Cytoskeletal rearrangements and transcriptional activation of c-fos serum response element by Rho-kinase.

    Kazuyasu Chihara;Mutsuki Amano;Nao Nakamura;Takeo Yano

  • Zipper-interacting Protein Kinase Induces Ca2+-free Smooth Muscle Contraction via Myosin Light Chain Phosphorylation

    Naohisa Niiro;Mitsuo Ikebe

  • Myosin X transports Mena/VASP to the tip of filopodia.

    Hiroshi Tokuo;Mitsuo Ikebe

  • Proteolysis of smooth muscle myosin by Staphylococcus aureus protease: preparation of heavy meromyosin and subfragment 1 with intact 20,000-dalton light chains

    M. Ikebe;David J. Hartshorne

  • Head-head and head-tail interaction: A general mechanism for switching off myosin II activity in cells

    HyunSuk Jung;Satoshi Komatsu;Mitsuo Ikebe;Roger W. Craig

  • Class VI myosin moves processively along actin filaments backward with large steps.

    So Nishikawa;Kazuaki Homma;Yasunori Komori;Mitsuhiro Iwaki

  • Proteolysis of smooth muscle myosin light chain kinase. Formation of inactive and calmodulin-independent fragments.

    M Ikebe;M Stepinska;B E Kemp;A R Means

  • The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation

    Hiroshi Tokuo;Katsuhide Mabuchi;Mitsuo Ikebe

  • Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response

    Masataka Sata;Harris Perlman;Daniel A. Muruve;Marcy Silver

  • Correlation of enzymatic properties and conformation of smooth muscle myosin.

    M. Ikebe;S. Hinkins;D. J. Hartshorne

  • Phosphorylation of smooth muscle myosin light chain kinase by Ca2+-activated, phospholipid-dependent protein kinase.

    M Ikebe;M Inagaki;K Kanamaru;H Hidaka

  • Agonist-induced changes in the phosphorylation of the myosin- binding subunit of myosin light chain phosphatase and CPI17, two regulatory factors of myosin light chain phosphatase, in smooth muscle

    Naohisa Niiro;Yasuhiko Koga;Mitsuo Ikebe

  • Effects of the regulatory light chain phosphorylation of myosin II on mitosis and cytokinesis of mammalian cells.

    Satoshi Komatsu;Takeo Yano;Masao Shibata;Richard A. Tuft

  • The cellular and molecular basis of bitter tastant-induced bronchodilation.

    Cheng-Hai Zhang;Lawrence M. Lifshitz;Karl F. Uy;Mitsuo Ikebe

  • The motor domain determines the large step of myosin-V.

    Hiroto Tanaka;Kazuaki Homma;Atsuko Hikikoshi Iwane;Eisaku Katayama;Eisaku Katayama

  • Ca2+-induced activation of ATPase activity of myosin Va is accompanied with a large conformational change.

    Xiang-dong Li;Katsuhide Mabuchi;Reiko Ikebe;Mitsuo Ikebe

Frequent Co-Authors

Hiroyuki Tanaka
Hiroyuki Tanaka Kyushu University
Roger Craig
Roger Craig University of Massachusetts Chan Medical School
Yale E. Goldman
Yale E. Goldman University of Pennsylvania
Masataka Sata
Masataka Sata University of Tokushima
Harry W. Schroeder
Harry W. Schroeder University of Alabama at Birmingham
Hanka Venselaar
Hanka Venselaar Radboud University
Soo Young Choi
Soo Young Choi Hallym University
David J. Hartshorne
David J. Hartshorne University of Arizona
Michael D. Ehlers
Michael D. Ehlers MPM BioImpact
Mike C. Payne
Mike C. Payne University of Cambridge

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