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Casper C. Hoogenraad

Casper C. Hoogenraad

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Biology and Biochemistry
Netherlands
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
100
Citations
33066
World Ranking
1537
National Ranking
27

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Casper C. Hoogenraad is affiliated with Utrecht University in the Netherlands. Their research is primarily situated within the broad field of Biochemistry, Genetics and Molecular Biology, with a focused output in Molecular Biology, Cell Biology, and Cellular and Molecular Neuroscience, alongside contributions to Physiology and Neurology. The scientist's work encompasses key topics including Microtubule and mitosis dynamics, Cellular transport and secretion, Endoplasmic Reticulum Stress and Disease, Neuroinflammation and Neurodegeneration Mechanisms, RNA Interference and Gene Delivery, Neurogenesis and neuroplasticity mechanisms, and Advanced biosensing and bioanalysis techniques.

Among the recent published works are:

  • Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics (2020, Nature Structural & Molecular Biology)
  • Correlating the Structure and Gene Silencing Activity of Oligonucleotide-Loaded Lipid Nanoparticles Using Small-Angle X-ray Scattering (2023, ACS Nano)
  • Predictive high-throughput screening of PEGylated lipids in oligonucleotide-loaded lipid nanoparticles for neuronal gene silencing (2022, Nanoscale Advances)
  • Specific KIF1A-adaptor interactions control selective cargo recognition (2021, The Journal of Cell Biology)
  • ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability (2021, Nature Communications)

Casper C. Hoogenraad has collaborated frequently with co-authors including Maarten Altelaar, Riccardo Stucchi, J.J.A. Hummel, Lukas C. Kapitein, and Sybren Portegies.

The scientist commonly publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Developmental Cell, eLife, and Nature Structural & Molecular Biology.

Casper C. Hoogenraad has been recognized as a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • The postsynaptic architecture of excitatory synapses: a more quantitative view.

    Morgan Sheng;Casper C. Hoogenraad

  • SynGO : An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

    Frank Koopmans;Pim van Nierop;Maria Andres-Alonso;Andrea Byrnes

  • Actin in dendritic spines: connecting dynamics to function

    Pirta Hotulainen;Casper C. Hoogenraad

  • Visualization of Microtubule Growth in Cultured Neurons via the Use of EB3-GFP (End-Binding Protein 3-Green Fluorescent Protein)

    Tatiana Stepanova;Jenny Slemmer;Casper C. Hoogenraad;Gideon Lansbergen

  • Dynamic Microtubules Regulate Dendritic Spine Morphology and Synaptic Plasticity

    Jacek Jaworski;Lukas C. Kapitein;Susana Montenegro Gouveia;Bjorn R. Dortland

  • Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury

    Farida Hellal;Andres Hurtado;Jörg Ruschel;Kevin C. Flynn

  • Control of Dendritic Arborization by the Phosphoinositide-3′-Kinase–Akt–Mammalian Target of Rapamycin Pathway

    Jacek Jaworski;Samantha Spangler;Daniel P. Seeburg;Casper C. Hoogenraad

  • Building the Neuronal Microtubule Cytoskeleton

    Lukas C. Kapitein;Casper C. Hoogenraad

  • Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

    Anna Akhmanova;Casper C. Hoogenraad;Ksenija Drabek;Tatiana Stepanova

  • Relative and Absolute Quantification of Postsynaptic Density Proteome Isolated from Rat Forebrain and Cerebellum

    Dongmei Cheng;Casper C. Hoogenraad;Casper C. Hoogenraad;John Rush;Elizabeth Ramm

  • TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites.

    Myrrhe van Spronsen;Myrrhe van Spronsen;Marina Mikhaylova;Marina Mikhaylova;Joanna Lipka;Joanna Lipka;Max A. Schlager

  • Microcircuitry and function of the inferior olive

    C. I. De Zeeuw;J. I. Simpson;C. C. Hoogenraad;N. Galjart

  • Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex.

    Theodoros Matanis;Anna Akhmanova;Phebe Wulf;Elaine Del Nery

  • STIM1 Is a MT-Plus-End-Tracking Protein Involved in Remodeling of the ER

    Ilya Grigoriev;Susana Montenegro Gouveia;Babet van der Vaart;Jeroen Demmers

  • Mammalian end binding proteins control persistent microtubule growth

    Yulia A. Komarova;Christian O. De Groot;Ilya Grigoriev;Susana Montenegro Gouveia

  • Microtubule plus-end-tracking proteins: Mechanisms and functions

    Anna Akhmanova;Casper C Hoogenraad

  • Synapse pathology in psychiatric and neurologic disease.

    Myrrhe van Spronsen;Casper C. Hoogenraad

  • Rab6 Regulates Transport and Targeting of Exocytotic Carriers

    Ilya Grigoriev;Daniël Splinter;Nanda Keijzer;Phebe S. Wulf

  • Mammalian Golgi‐associated Bicaudal‐D2 functions in the dynein–dynactin pathway by interacting with these complexes

    Casper C. Hoogenraad;Anna Akhmanova;Steven A. Howell;Bjorn R. Dortland

  • Mixed Microtubules Steer Dynein-Driven Cargo Transport into Dendrites

    Lukas C. Kapitein;Max A. Schlager;Marijn Kuijpers;Phebe S. Wulf

Frequent Co-Authors

Anna Akhmanova
Anna Akhmanova Utrecht University
Lukas C. Kapitein
Lukas C. Kapitein Utrecht University
Michel O. Steinmetz
Michel O. Steinmetz Paul Scherrer Institute
Dick Jaarsma
Dick Jaarsma Erasmus University Rotterdam
Chris I. De Zeeuw
Chris I. De Zeeuw Erasmus University Rotterdam
Niels Galjart
Niels Galjart Erasmus University Rotterdam
R. Jeroen Pasterkamp
R. Jeroen Pasterkamp Utrecht University
Morgan Sheng
Morgan Sheng Broad Institute
Frank Grosveld
Frank Grosveld Erasmus University Rotterdam

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