World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
18289
World Ranking
3593
National Ranking
1796

Overview

R. John Solaro is affiliated with the University of Illinois at Chicago in the United States. Their research focuses primarily on medicine and biochemistry, genetics, and molecular biology, with significant contributions to cardiology and cardiovascular medicine and molecular biology as subfields of study.

The main topics covered in Solaro's work include:

  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Effects of Exercise
  • Cardiac electrophysiology and arrhythmias
  • Viral Infections and Immunology Research
  • Congenital heart defects research
  • Ion channel regulation and function
  • Atrial Fibrillation Management and Outcomes

Solaro has contributed to a number of recent papers, reflecting the focus on cardiac physiology and molecular mechanisms. These recent papers include:

  • "JNK2, a Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca 2+ ] SR Leak-Load Relationship," published in 2020 in Circulation Research
  • "Novel insights into sarcomere regulatory systems control of cardiac thin filament activation," published in 2021 in The Journal of General Physiology
  • "Mechanisms of Arrhythmogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant I79N," published in 2021 in Frontiers in Cell and Developmental Biology
  • "Binding of calcium and magnesium to human cardiac troponin C," published in 2021 in Journal of Biological Chemistry
  • "Implications of the complex biology and micro-environment of cardiac sarcomeres in the use of high affinity troponin antibodies as serum biomarkers for cardiac disorders," published in 2020 in Journal of Molecular and Cellular Cardiology

Frequent coauthors collaborating with Solaro include:

  • Beata M. Wolska
  • Chad M. Warren
  • Paul H. Goldspink
  • Paulina Langa
  • Andrielle Elaine Capote

Solaro publishes regularly in several scientific journals, with multiple publications in the following venues:

  • Journal of Molecular and Cellular Cardiology
  • Circulation Research
  • Frontiers in Physiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation

Best Publications

  • Regulation of cardiac contractile function by troponin I phosphorylation

    Joanne Layland;R. John Solaro;Ajay M. Shah

  • Impaired cardiomyocyte relaxation and diastolic function in transgenic mice expressing slow skeletal troponin I in the heart

    Richard C. Fentzke;Scott H. Buck;Jitandrakumar R. Patel;Hua Lin

  • Cardiac Troponin I Mutants PHOSPHORYLATION BY PROTEIN KINASES C AND A AND REGULATION OF Ca2+-STIMULATED MgATPase OF RECONSTITUTED ACTOMYOSIN S-1

    Thomas A. Noland;Xiaodu Guo;Robert L. Raynor;Nathan M. Jideama

  • S-Glutathionylation of Cryptic Cysteines Enhances Titin Elasticity by Blocking Protein Folding

    Jorge Alegre-Cebollada;Pallav Kosuri;David Giganti;Edward Eckels

  • Mouse Model of a Familial Hypertrophic Cardiomyopathy Mutation in α-Tropomyosin Manifests Cardiac Dysfunction

    Mariappan Muthuchamy;Kathy Pieples;Prabhakar Rethinasamy;Brian Hoit

  • Ranolazine Improves Cardiac Diastolic Dysfunction Through Modulation of Myofilament Calcium Sensitivity

    Joshua D. Lovelock;Michelle M. Monasky;Euy Myoung Jeong;Harvey A. Lardin

  • Stereoselective actions of thiadiazinones on canine cardiac myocytes and myofilaments.

    R J Solaro;G Gambassi;D M Warshaw;M R Keller

  • Augmented Protein Kinase C-α–Induced Myofilament Protein Phosphorylation Contributes to Myofilament Dysfunction in Experimental Congestive Heart Failure

    Rashad J. Belin;Marius P. Sumandea;Edward J. Allen;Kelly Schoenfelt

  • Troponin I in the murine myocardium: influence on length‐dependent activation and interfilament spacing

    John P. Konhilas;Thomas C. Irving;Beata M. Wolska;Eias E. Jweied

  • Increased Ca2+ Affinity of Cardiac Thin Filaments Reconstituted with Cardiomyopathy-related Mutant Cardiac Troponin I

    Tomoyoshi Kobayashi;R. John Solaro

  • The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation.

    R. John Solaro;Paul Rosevear;Tomoyoshi Kobayashi

  • A Novel Cardiomyocyte-enriched MicroRNA, miR-378, Targets Insulin-like Growth Factor 1 Receptor IMPLICATIONS IN POSTNATAL CARDIAC REMODELING AND CELL SURVIVAL

    Ivana Knezevic;Aalok Patel;Nagalingam R. Sundaresan;Mahesh P. Gupta

  • Molecular and Physiological Effects of α-Tropomyosin Ablation in the Mouse

    Prabhakar Rethinasamy;Mariappan Muthuchamy;Tim Hewett;Greg Boivin

  • Intracellular Localization and Functional Effects of P21-Activated Kinase-1 (Pak1) in Cardiac Myocytes

    Yunbo Ke;Lynn Wang;W. Glen Pyle;Pieter P. de Tombe

  • Integration of Troponin I Phosphorylation With Cardiac Regulatory Networks

    R. John Solaro;Marcus Henze;Tomoyoshi Kobayashi

  • Multiplex kinase signaling modifies cardiac function at the level of sarcomeric proteins.

    R. John Solaro

  • The C Terminus of Cardiac Troponin I Is Essential for Full Inhibitory Activity and Ca2+ Sensitivity of Rat Myofibrils *

    Helen M. Rarick;Xiong Hai Tu;R. John Solaro;Anne F. Martin

  • Research Priorities in Hypertrophic Cardiomyopathy Report of a Working Group of the National Heart, Lung, and Blood Institute

    Thomas Force;Robert O. Bonow;Steven R. Houser;R. John Solaro

  • Effects of thin and thick filament proteins on calcium binding and exchange with cardiac troponin C.

    Jonathan P. Davis;Catalina Norman;Tomoyoshi Kobayashi;R. John Solaro

  • Disruption of Integrin Function in the Murine Myocardium Leads to Perinatal Lethality, Fibrosis, and Abnormal Cardiac Performance

    Rebecca S. Keller;Shaw Yung Shai;Christopher J. Babbitt;Can G. Pham

Frequent Co-Authors

Pieter P. de Tombe
Pieter P. de Tombe University of Illinois at Chicago
Stephen B. Liggett
Stephen B. Liggett University of South Florida
Evangelia G. Kranias
Evangelia G. Kranias University of Cincinnati Medical Center
Arnold Schwartz
Arnold Schwartz University of Cincinnati
Mahesh P. Gupta
Mahesh P. Gupta University of Chicago
Jonathan Chernoff
Jonathan Chernoff Fox Chase Cancer Center
Rui-Ping Xiao
Rui-Ping Xiao Peking University
Samuel C. Dudley
Samuel C. Dudley University of Minnesota
Richard L. Moss
Richard L. Moss University of Wisconsin–Madison
Alan P. Koretsky
Alan P. Koretsky National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you are interested in broadening your professional options beyond Biology and Biochemistry, a variety of related online degrees can open new doors in the health and science sectors. For students seeking leadership roles, doctoral programs for healthcare administration provide a pathway to management positions within hospitals, research centers, or public health organizations.

Those interested in advanced nursing without the need for hands-on training can consider a dnp program without clinical hours, offering flexibility and a focus on leadership, policy, and evidence-based practice.

If pharmacy appeals to you, explore the options available in pharmd online programs, which prepare graduates for pharmaceutical research, clinical roles, and even business pathways within the pharmaceutical industry.

Alternatively, those passionate about health, wellness, and physical performance can check out fitness degrees online. These programs offer essential knowledge for careers as fitness coaches, exercise physiologists, or wellness consultants.

With online learning, you can tailor your studies to your career interests while balancing work or other commitments—making it easier than ever to advance in the science and health fields.

Best Scientists Citing R. John Solaro

Trending Scientists

Recently Published Articles