Stephen B. Liggett

Research.com Recognitions

• 2018 - Fellow of the Indian National Academy of Engineering (INAE)
• 2014 - Fellow of the American Association for the Advancement of Science (AAAS)
• 2013 - Fellow, National Academy of Inventors
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness.

  Connie M. Drysdale;Dennis W. McGraw;Catharine B. Stack;J. Claiborne Stephens

  1217
  Citations

• Amino-terminal polymorphisms of the human beta 2-adrenergic receptor impart distinct agonist-promoted regulatory properties.

  Stuart A. Green;Jamal Turki;Michael Innis;Stephen B. Liggett

  1184
  Citations

• Transgenic Gαq overexpression induces cardiac contractile failure in mice

  Drew D. D’Angelo;Yoshihito Sakata;John N. Lorenz;Gregory P. Boivin

  947
  Citations

• Mutations in the Gene Encoding for the β2-adrenergic Receptor in Normal and Asthmatic Subjects

  Ellen Reihsaus;Michael Innis;Neil MacIntyre;Stephen B. Liggett

  924
  Citations

• A Gain-of-function Polymorphism in a G-protein Coupling Domain of the Human β1-Adrenergic Receptor

  D A Mason;J D Moore;S A Green;S B Liggett

  882
  Citations

• The Effect of Polymorphisms of the β2-Adrenergic Receptor on the Response to Regular Use of Albuterol in Asthma

  Elliot Israel;Jeffrey M. Drazen;Stephen B. Liggett;Homer A. Boushey

  772
  Citations

• PKC-alpha regulates cardiac contractility and propensity toward heart failure.

  Julian C Braz;Kimberly Gregory;Anand Pathak;Wen Zhao

  730
  Citations

• Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial

  Elliot Israel;Vernon M. Chinchilli;Jean G. Ford;Homer A. Boushey

  708
  Citations

• Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction.

  Deepak A Deshpande;Wayne C H Wang;Elizabeth L McIlmoyle;Kathryn S Robinett

  703
  Citations

• A polymorphism of the human beta 2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor.

  S A Green;G Cole;M Jacinto;M Innis

  692
  Citations

• Enhanced Gαq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure

  John W. Adams;Yoshihito Sakata;Michael G. Davis;Valerie P. Sah

  688
  Citations

• Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure.

  Kersten M. Small;Lynne E. Wagoner;Albert M. Levin;Sharon L R Kardia

  666
  Citations

• Sequencing and Analyses of All Known Human Rhinovirus Genomes Reveal Structure and Evolution

  Ann C. Palmenberg;David Spiro;Ryan Kuzmickas;Shiliang Wang

  602
  Citations

• Genetic polymorphisms of the beta 2-adrenergic receptor in nocturnal and nonnocturnal asthma. Evidence that Gly16 correlates with the nocturnal phenotype.

  J Turki;J Pak;S A Green;R J Martin

  580
  Citations

• Early and Delayed Consequences of β2-Adrenergic Receptor Overexpression in Mouse Hearts Critical Role for Expression Level

  Stephen B. Liggett;Nicole M. Tepe;John N. Lorenz;Amy M. Canning

  570
  Citations

• Influence of beta 2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells.

  S A Green;J Turki;P Bejarano;I P Hall

  559
  Citations

• Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human

  Kobra Haghighi;Fotis Kolokathis;Luke Pater;Roy A. Lynch

  508
  Citations

• The Ile164 beta2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure.

  Stephen B. Liggett;Lynne E. Wagoner;Laura L. Craft;Richard W. Hornung

  506
  Citations

• A polymorphism within a conserved β1-adrenergic receptor motif alters cardiac function and β-blocker response in human heart failure

  Stephen B. Liggett;Jeanne Mialet-Perez;Surai Thaneemit-Chen;Stewart A. Weber

  494
  Citations

• Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure.

  Jeanne Mialet Perez;Deborah A Rathz;Natalia N Petrashevskaya;Harvey S Hahn

  482
  Citations