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Biology and Biochemistry

D-Index
117
Citations
67859
World Ranking
710
National Ranking
451

Overview

Gerald W. Dorn is affiliated with Washington University in St. Louis, United States. Their research spans several interconnected fields, primarily centered around biochemistry, genetics, and molecular biology, with significant contributions also in medicine and neuroscience.

The scientist's academic work focuses on specialized subfields including molecular biology, neurology, epidemiology, cellular and molecular neuroscience, and cardiology and cardiovascular medicine. This interdisciplinary approach supports their study of mitochondrial function, autophagy, metabolic and genetic disorders, and neurological diseases.

Gerald W. Dorn's published papers reflect a strong emphasis on mitochondrial biology. Notable recent publications include:

  • Mitofusins as mitochondrial anchors and tethers (2020) published in the Journal of Molecular and Cellular Cardiology
  • Mitofusin 2 Dysfunction and Disease in Mice and Men (2020) published in Frontiers in Physiology

Additional recent influential work relevant to mitochondrial autophagy and neuromuscular dysfunction includes papers published in high-profile journals such as eLife, Cell Death and Disease, and Nature Communications. While Gerald W. Dorn is not the lead author on these papers, they reflect current topics within their research community:

  • Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy (2022), Cell Death and Disease
  • Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A (2020), eLife
  • TDP-43 and PINK1 mediate CHCHD10S59L mutation-induced defects in Drosophila and in vitro (2021), Nature Communications

Frequent co-authors collaborating with Gerald W. Dorn include Antonietta Franco, Xiawei Dang, Robert H. Baloh, Jiajia Li, and Emily K. Walton.

The scientist has contributed multiple publications to journals such as Cells, eLife, Cardiovascular Research, Journal of Molecular and Cellular Cardiology, and Cell Death and Disease. Their considerable output includes 31 publications in biochemistry, genetics, and molecular biology; 22 in medicine; and 12 in neuroscience.

Key research topics associated with their work encompass:

  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research
  • Autophagy in Disease and Therapy
  • Neurological Diseases and Metabolism
  • Metabolism and Genetic Disorders
  • Amyotrophic Lateral Sclerosis Research
  • Genetic Neurodegenerative Diseases

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

    Christopher P. Baines;Robert A. Kaiser;Nicole H. Purcell;N. Scott Blair

  • MicroRNA-133 controls cardiac hypertrophy

    Alessandra Carè;Daniele Catalucci;Federica Felicetti;Désirée Bonci

  • PINK1- Phosphorylated Mitofusin 2 is a Parkin Receptor for Culling Damaged Mitochondria

    Yun Chen;Gerald W. Dorn

  • Transgenic Gαq overexpression induces cardiac contractile failure in mice

    Drew D. D’Angelo;Yoshihito Sakata;John N. Lorenz;Gregory P. Boivin

  • Cytoplasmic Signaling Pathways That Regulate Cardiac Hypertrophy

    Jeffery D Molkentin;Gerald W Dorn

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • RAS Point Mutations and PAX8-PPARγ Rearrangement in Thyroid Tumors: Evidence for Distinct Molecular Pathways in Thyroid Follicular Carcinoma

    Marina N. Nikiforova;Roy A. Lynch;Paul W. Biddinger;Erik K. Alexander

  • Protein kinase cascades in the regulation of cardiac hypertrophy

    Gerald W. Dorn;Thomas Force

  • Enhanced Gαq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure

    John W. Adams;Yoshihito Sakata;Michael G. Davis;Valerie P. Sah

  • Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and ɛPKC

    Leon Chen;Harvey Hahn;Guangyu Wu;Che Hong Chen

  • Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming

    Wen Xing Ding;Wen Xing Ding;Hong Min Ni;Hong Min Ni;Min Li;Yong Liao

  • Early and Delayed Consequences of β2-Adrenergic Receptor Overexpression in Mouse Hearts Critical Role for Expression Level

    Stephen B. Liggett;Nicole M. Tepe;John N. Lorenz;Amy M. Canning

  • Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and Gαq Overexpression–Induced Heart Failure

    Dao Fu Dai;Simon C. Johnson;Jason J. Villarin;Michael T. Chin

  • Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human

    Kobra Haghighi;Fotis Kolokathis;Luke Pater;Roy A. Lynch

  • miR-15 Family Regulates Postnatal Mitotic Arrest of Cardiomyocytes

    Enzo R. Porrello;Brett A. Johnson;Arin B. Aurora;Emma Simpson

  • Mitochondrial biogenesis and dynamics in the developing and diseased heart

    Gerald W. Dorn;Rick B. Vega;Daniel P. Kelly

  • Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure.

    Jeanne Mialet Perez;Deborah A Rathz;Natalia N Petrashevskaya;Harvey S Hahn

  • MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-Overloaded Adult Hearts

    Scot J. Matkovich;Wei Wang;Yizheng Tu;William H. Eschenbacher

Frequent Co-Authors

Evangelia G. Kranias
Evangelia G. Kranias University of Cincinnati Medical Center
Stephen B. Liggett
Stephen B. Liggett University of South Florida
Erhe Gao
Erhe Gao Temple University
Walter J. Koch
Walter J. Koch Temple University
Joan Heller Brown
Joan Heller Brown University of California, San Diego
Paul I. W. de Bakker
Paul I. W. de Bakker Vertex Pharmaceuticals (United Kingdom)
Jeffery D. Molkentin
Jeffery D. Molkentin Cincinnati Children's Hospital Medical Center
Jeffrey Robbins
Jeffrey Robbins Cincinnati Children's Hospital Medical Center
Robert Clarke
Robert Clarke University of Oxford
Bruno Trimarco
Bruno Trimarco University of Naples Federico II

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