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Neuroscience

D-Index
49
Citations
13874
World Ranking
5877
National Ranking
2582

Overview

Tzumin Lee is affiliated with the Howard Hughes Medical Institute in the United States. Their research spans key areas within biochemistry, genetics, and molecular biology, with specific focus on agricultural and biological sciences. The main topics addressed in their work include neurobiology and insect physiology research, CRISPR and genetic engineering, single-cell and spatial transcriptomics, genetics, aging, and longevity studies in model organisms, plant molecular biology research, insect and arachnid ecology and behavior, and animal behavior and reproduction.

Lee's recent publications demonstrate a diverse range of study topics and collaborative projects. Notable papers include:

  • "Conservation and divergence of related neuronal lineages in the Drosophila central brain," 2020, published in eLife
  • "Metamorphosis of memory circuits in Drosophila reveals a strategy for evolving a larval brain," 2023, published in eLife
  • "A programmable sequence of reporters for lineage analysis," 2020, published in Nature Neuroscience
  • "Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation," 2020, published in Biology Open
  • "Driver lines for studying associative learning in Drosophila," 2023, published in bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators in Lee's research include Rosa Linda Miyares, Isabel Espinosa-Medina, Ching-Po Yang, Jorge García-Marqués, and Yoshinori Aso. These collaborations have contributed to advancing research in multiple areas within molecular and cellular neuroscience as well as genetics.

Lee's publication history shows a significant presence in several scientific journals and platforms, most notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Methods in Molecular Biology
  • Nature Neuroscience
  • Neuron

Their research portfolio also covers various subfields, including molecular biology, cellular and molecular neuroscience, plant science, aging, and genetics. This breadth reflects an interdisciplinary approach addressing both molecular mechanisms and broader biological systems.

Best Publications

  • Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis.

    Tzumin Lee;Liqun Luo

  • Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila.

    Fillip Port;Hui-Min Chen;Tzumin Lee;Simon L. Bullock

  • Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development

    Tzumin Lee;Liqun Luo

  • Development of the Drosophila mushroom bodies: sequential generation of three distinct types of neurons from a neuroblast

    Tzumin Lee;Arthur Lee;Liqun Luo

  • Genetic mosaic with dual binary transcriptional systems in Drosophila.

    Sen-Lin Lai;Sen-Lin Lai;Tzumin Lee;Tzumin Lee

  • Essential Roles of Drosophila RhoA in the Regulation of Neuroblast Proliferation and Dendritic but Not Axonal Morphogenesis

    Tzumin Lee;Christopher Winter;Simone S Marticke;Arthur Lee

  • Organization and Postembryonic Development of Glial Cells in the Adult Central Brain of Drosophila

    Takeshi Awasaki;Sen-Lin Lai;Kei Ito;Tzumin Lee

  • Cell-Autonomous Requirement of the USP/EcR-B Ecdysone Receptor for Mushroom Body Neuronal Remodeling in Drosophila

    Tzumin Lee;Simone Marticke;Carl Sung;Steven Robinow

  • Sparse, decorrelated odor coding in the mushroom body enhances learned odor discrimination

    Andrew C Lin;Alexei M Bygrave;Alix de Calignon;Tzumin Lee

  • Drosophila Sensory Neurons Require Dscam for Dendritic Self-Avoidance and Proper Dendritic Field Organization

    Peter Soba;Sijun Zhu;Kazuo Emoto;Susan H Younger

  • Drosophila Dscam is required for divergent segregation of sister branches and suppresses ectopic bifurcation of axons.

    Jian Wang;Christopher T Zugates;Inray H Liang;Ching-Hsien J Lee

  • TGF-β Signaling Activates Steroid Hormone Receptor Expression during Neuronal Remodeling in the Drosophila Brain

    Xiaoyan Zheng;Jian Wang;Theodor E. Haerry;Ann Y.H. Wu

  • Gradients of the Drosophila Chinmo BTB-Zinc Finger Protein Govern Neuronal Temporal Identity

    Sijun Zhu;Suewei Lin;Chih-Fei Kao;Takeshi Awasaki

  • A Complete Developmental Sequence of a Drosophila Neuronal Lineage as Revealed by Twin-Spot MARCM

    Hung Hsiang Yu;Chih-Fei Kao;Yisheng He;Peng Ding

  • Clonal analysis of Drosophila antennal lobe neurons: diverse neuronal architectures in the lateral neuroblast lineage.

    Sen-Lin Lai;Takeshi Awasaki;Takeshi Awasaki;Kei Ito;Tzumin Lee

  • Transmembrane/juxtamembrane domain-dependent Dscam distribution and function during mushroom body neuronal morphogenesis.

    Jian Wang;Xiaojun Ma;Jacob S. Yang;Xiaoyan Zheng

  • Glia instruct developmental neuronal remodeling through TGF-[beta] signaling

    Takeshi Awasaki;Yaling Huang;Yaling Huang;Michael B O'Connor;Tzumin Lee;Tzumin Lee

  • Twin-spot MARCM to reveal the developmental origin and identity of neurons

    Hung-Hsiang Yu;Chun-Hong Chen;Lei Shi;Yaling Huang

  • Opposing intrinsic temporal gradients guide neural stem cell production of varied neuronal fates

    Zhiyong Liu;Ching-Po Yang;Ken Sugino;Chi-Cheng Fu;Chi-Cheng Fu

  • A pair of inhibitory neurons are required to sustain labile memory in the Drosophila mushroom body

    Jena L. Pitman;Wolf Huetteroth;Christopher J. Burke;Michael Jonathan Krashes

  • Serotonin–mushroom body circuit modulating the formation of anesthesia-resistant memory in Drosophila

    Pei-Tseng Lee;Hsuan-Wen Lin;Yu-Hsuan Chang;Tsai-Feng Fu

Frequent Co-Authors

Luke P. Lee
Luke P. Lee University of California, Berkeley
Liqun Luo
Liqun Luo Stanford University
Kei Ito
Kei Ito University of Cologne
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco
Aljoscha Nern
Aljoscha Nern Howard Hughes Medical Institute
Scott Waddell
Scott Waddell University of Oxford
Michael J. Krashes
Michael J. Krashes National Institutes of Health

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