World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
59
Citations
12543
World Ranking
10128
National Ranking
2816

Biology and Biochemistry

D-Index
62
Citations
13358
World Ranking
10830
National Ranking
4699

Overview

Ying Ge is affiliated with the University of Wisconsin-Madison in the United States. Their research primarily intersects the fields of biochemistry, genetics, molecular biology, medicine, and chemistry, with substantial contributions to subfields including molecular biology, spectroscopy, cardiology and cardiovascular medicine, surgery, and oncology.

The scientist's work focuses largely on advanced proteomics techniques and applications, as well as mass spectrometry techniques and applications. Other major research topics include metabolomics and mass spectrometry studies, cardiomyopathy and myosin studies, tissue engineering and regenerative medicine, RNA and protein synthesis mechanisms, and analytical chemistry and chromatography.

Ying Ge has published extensively in a range of academic journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Proteome Research
  • Analytical Chemistry
  • Journal of the American Chemical Society
  • Journal of the American Society for Mass Spectrometry

Their recent papers demonstrate a focus on proteomics and mass spectrometry, including:

  • "The Human Proteoform Project: Defining the human proteome" (2021) in Science Advances
  • "Novel Strategies to Address the Challenges in Top-Down Proteomics" (2021) in Journal of the American Society for Mass Spectrometry
  • "Top-down proteomics: challenges, innovations, and applications in basic and clinical research" (2020) in Expert Review of Proteomics
  • "Higher-order structural characterisation of native proteins and complexes by top-down mass spectrometry" (2020) in Chemical Science
  • "Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry" (2020) in Journal of the American Society for Mass Spectrometry

They collaborate frequently with other researchers in related fields. Among frequent co-authors are David S. Roberts, Yanlong Zhu, Kyle A. Brown, Jake A. Melby, and Song Jin, reflecting active engagement in collaborative academic research.

Best Publications

  • How many human proteoforms are there

    Ruedi Aebersold;Jeffrey N. Agar;I. Jonathan Amster;Mark S. Baker

  • Cardiac Repair in a Porcine Model of Acute Myocardial Infarction with Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells

    Lei Ye;Ying Hua Chang;Qiang Xiong;Pengyuan Zhang

  • Top down characterization of larger proteins (45 kDa) by electron capture dissociation mass spectrometry.

    Ying Ge;Brian G Lawhorn;Mariam ElNaggar;Erick Strauss

  • Large Cardiac Muscle Patches Engineered From Human Induced-Pluripotent Stem Cell-Derived Cardiac Cells Improve Recovery From Myocardial Infarction in Swine.

    Ling Gao;Zachery R. Gregorich;Wuqiang Zhu;Saidulu Mattapally

  • Activated ion electron capture dissociation for mass spectral sequencing of larger (42 kDa) proteins.

    David M. Horn;Ying Ge;Fred W. Mclafferty

  • Best practices and benchmarks for intact protein analysis for top-down mass spectrometry.

    Daniel P. Donnelly;Catherine M. Rawlins;Caroline J. DeHart;Luca Fornelli

  • Top-down mass spectrometry of a 29-kDa protein for characterization of any posttranslational modification to within one residue.

    Siu Kwan Sze;Ying Ge;HanBin Oh;Fred W. McLafferty

  • Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance.

    Fred W. McLafferty;David M. Horn;Kathrin Breuker;Ying Ge

  • Secondary and tertiary structures of gaseous protein ions characterized by electron capture dissociation mass spectrometry and photofragment spectroscopy.

    HanBin Oh;Kathrin Breuker;Siu Kwan Sze;Ying Ge

  • Top‐down proteomics in health and disease: Challenges and opportunities

    Zachery R. Gregorich;Ying Ge

  • The Human Proteoform Project: Defining the human proteome.

    Lloyd M. Smith;Jeffrey N. Agar;Julia Chamot-Rooke;Paul O. Danis

  • Identification and Quantification of Proteoforms by Mass Spectrometry.

    Leah V. Schaffer;Robert J. Millikin;Rachel M. Miller;Lissa C. Anderson

  • Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure.

    Jiang Zhang;Moltu J. Guy;Holly S. Norman;Yi Chen Chen

  • Top-Down Proteomics: Ready for Prime Time?

    Bifan Chen;Kyle A. Brown;Ziqing Lin;Ying Ge

  • Comprehensive Analysis of Protein Modifications by Top-down Mass Spectrometry

    Han Zhang;Ying Ge

  • Top-down high-resolution mass spectrometry of cardiac myosin binding protein C revealed that truncation alters protein phosphorylation state

    Ying Ge;Inna N. Rybakova;Qingge Xu;Richard L. Moss

  • Novel Strategies to Address the Challenges in Top-Down Proteomics.

    Jake A. Melby;David S. Roberts;Eli J. Larson;Kyle A. Brown

  • Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR)

    Seung-Hyeon Seok;Zhi-Xiong Ma;John B. Feltenberger;Hongbo Chen

  • Forging Isopeptide Bonds Using Thiol–Ene Chemistry: Site-Specific Coupling of Ubiquitin Molecules for Studying the Activity of Isopeptidases

    Ellen M. Valkevich;Robert G. Guenette;Nicholas A. Sanchez;Yi-chen Chen

  • MASH Suite Pro: A Comprehensive Software Tool for Top-Down Proteomics.

    Wenxuan Cai;Wenxuan Cai;Huseyin Guner;Huseyin Guner;Zachery R. Gregorich;Zachery R. Gregorich;Albert J. Chen

  • Unraveling Molecular Complexity of Phosphorylated Human Cardiac Troponin I by Top Down Electron Capture Dissociation/Electron Transfer Dissociation Mass Spectrometry

    Vlad Zabrouskov;Ying Ge;Jae Schwartz;Jeffery W. Walker

  • Biosynthesis of the thiazole moiety of thiamin in Escherichia coli: identification of an acyldisulfide-linked protein--protein conjugate that is functionally analogous to the ubiquitin/E1 complex.

    Jun Xi;Ying Ge;Cynthia Kinsland;Fred W. McLafferty

Frequent Co-Authors

Song Jin
Song Jin University of Wisconsin–Madison
Fred W. McLafferty
Fred W. McLafferty Cornell University
Neil L. Kelleher
Neil L. Kelleher Northwestern University
Lloyd M. Smith
Lloyd M. Smith University of Wisconsin–Madison
Richard L. Moss
Richard L. Moss University of Wisconsin–Madison
Timothy J. Kamp
Timothy J. Kamp University of Wisconsin–Madison
Joseph A. Loo
Joseph A. Loo University of California, Los Angeles
Han Zhang
Han Zhang Shenzhen University
Paul M. Thomas
Paul M. Thomas Northwestern University
Ljiljana Paša-Tolić
Ljiljana Paša-Tolić Environmental Molecular Sciences Laboratory

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