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Chemistry

D-Index
97
Citations
33489
World Ranking
1468
National Ranking
564

Overview

Joseph A. Loo is affiliated with the University of California, Los Angeles in the United States. Their research spans multiple fields, with a focus on spectroscopy, molecular biology, and neurology, among others. The scientist's work extends into materials chemistry and the history and philosophy of science.

The main topics covered in Joseph A. Loo's research include academic writing and publishing, mass spectrometry techniques and applications, and advanced proteomics techniques and applications. Other significant areas of investigation include enzyme structure and function, analytical chemistry and chromatography, ion-surface interactions and analysis, and metabolomics and mass spectrometry studies.

Joseph A. Loo has coauthored frequently with several researchers. The most frequent collaborators include John R. Yates, Cynthia J. Burrows, Shu Wang, Hyun Jae Kim, and Gerald J. Meyer.

The scientist's recent papers cover diverse subjects within their expertise. Notable publications include:

  • The Human Proteoform Project: Defining the human proteome (2021, Science Advances)
  • Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43 (2022, Nature)
  • Higher-order structural characterisation of native proteins and complexes by top-down mass spectrometry (2020, Chemical Science)
  • Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry (2020, Journal of the American Society for Mass Spectrometry)
  • PEPPI-MS: Polyacrylamide-Gel-Based Prefractionation for Analysis of Intact Proteoforms and Protein Complexes by Mass Spectrometry (2020, Journal of Proteome Research)

Joseph A. Loo has published extensively in several scientific journals. The most frequent publication venues include:

  • Journal of the American Society for Mass Spectrometry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Proteome Research
  • Journal of the American Chemical Society
  • Analytical Chemistry

Best Publications

  • Studying noncovalent protein complexes by electrospray ionization mass spectrometry

    Joseph A. Loo

  • New developments in biochemical mass spectrometry: electrospray ionization

    Richard D. Smith;Joseph A. Loo;Charles G. Edmonds;Charles J. Barinaga

  • How many human proteoforms are there

    Ruedi Aebersold;Jeffrey N. Agar;I. Jonathan Amster;Mark S. Baker

  • Principles and practice of electrospray ionization—mass spectrometry for large polypeptides and proteins

    Richard D. Smith;Joseph A. Loo;Rachel R. Ogorzalek Loo;Mark Busman

  • Electrospray ionization mass spectrometry: a technology for studying noncovalent macromolecular complexes

    Joseph A Loo

  • Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

    David W. Fry;Alexander J. Bridges;William A. Denny;Annette Doherty

  • The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions

    Paul Denny;Fred K. Hagen;Markus Hardt;Lujian Liao

  • Use of Proteomics to Demonstrate a Hierarchical Oxidative Stress Response to Diesel Exhaust Particle Chemicals in a Macrophage Cell Line

    Gary Guishan Xiao;Gary Guishan Xiao;Meiying Wang;Ning Li;Joseph A. Loo

  • Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas.

    Robert Newcomb;Balazs Szoke;Andrew Palma;Gang Wang

  • Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis-mass spectrometry.

    Shen Hu;Yongming Xie;Prasanna Ramachandran;Rachel R. Ogorzalek Loo

  • Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions.

    J. B. Smaill;G. W. Rewcastle;J. A. Loo;K. D. Greis

  • Effect of reducing disulfide-containing proteins on electrospray ionization mass spectra.

    Joseph A. Loo;Charles G. Edmonds;Harold R. Udseth;Richard D. Smith

  • Enhanced FASP (eFASP) to increase proteome coverage and sample recovery for quantitative proteomic experiments.

    Jonathan Erde;Rachel R. Ogorzalek Loo;Joseph A. Loo

  • Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane

    Steven M. Claypool;Yavuz Oktay;Pinmanee Boontheung;Joseph A. Loo

  • Best practices and benchmarks for intact protein analysis for top-down mass spectrometry.

    Daniel P. Donnelly;Catherine M. Rawlins;Caroline J. DeHart;Luca Fornelli

  • Solvent-induced conformational changes of polypeptides probed by electrospray-ionization mass spectrometry.

    Joseph A. Loo;Rachel R. Ogorzalek Loo;Harold R. Udseth;Charles G. Edmonds

  • Peptide and protein analysis by electrospray ionization-mass spectrometry and capillary electrophoresis-mass spectrometry.

    Joseph A. Loo;Harold R. Udseth;Richard D. Smith

  • Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins

    Sharmistha Sinha;Dahabada H. J. Lopes;Zhenming Du;Eric S. Pang

  • Primary sequence information from intact proteins by electrospray ionization tandem mass spectrometry

    Joseph A. Loo;Charles G. Edmonds;Richard D. Smith

  • Collisional effects on the charge distribution of ions from large molecules, formed by electrospray‐ionization mass spectrometry

    Joseph A. Loo;Harold R. Udseth;Richard D. Smith;J. H. Futrell

Frequent Co-Authors

John R. Yates
John R. Yates Scripps Research Institute
Carolyn R. Bertozzi
Carolyn R. Bertozzi Stanford University
Gilbert C. Walker
Gilbert C. Walker University of Toronto
Stuart J. Rowan
Stuart J. Rowan University of Chicago
Prashant V. Kamat
Prashant V. Kamat University of Notre Dame
Marc A. Hillmyer
Marc A. Hillmyer University of Minnesota
Vincent M. Rotello
Vincent M. Rotello University of Massachusetts Amherst
Gregory D. Scholes
Gregory D. Scholes Princeton University

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