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Genetics
UK
2024
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Genetics and Molecular Biology
UK
2024

D-Index & Metrics

Genetics

D-Index
137
Citations
81518
World Ranking
206
National Ranking
39

Medicine

D-Index
138
Citations
83416
World Ranking
1811
National Ranking
188

Research.com Recognitions

  • 2024 - Research.com Genetics in United Kingdom Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
  • 2023 - Research.com Genetics in United Kingdom Leader Award
  • 2001 - Fellow of the Royal Society, United Kingdom

Overview

Bruce A.J. Ponder is affiliated with the University of Cambridge in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with additional contributions in Medicine. Their work covers several subfields including Molecular Biology, Cancer Research, Pulmonary and Respiratory Medicine, Genetics, and Oncology.

The scientist's main topics of research include:

  • Cancer-related molecular mechanisms research
  • Ferroptosis and cancer prognosis
  • Genomics and Chromatin Dynamics
  • Genetic Associations and Epidemiology
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Bioinformatics and Genomic Networks

Among their recent papers are the following:

  • "Smoking-associated gene expression alterations in nasal epithelium reveal immune impairment linked to lung cancer risk," published in 2024 in Genome Medicine
  • "Identification of candidate causal variants and target genes at 41 breast cancer risk loci through differential allelic expression analysis," published in 2024 in Scientific Reports
  • "Mapping of cis-regulatory variants by differential allelic expression analysis identifies candidate causal variants and target genes of 41 breast cancer risk loci," published in 2022 in bioRxiv (Cold Spring Harbor Laboratory)
  • "Multi-cohort analysis identifies a blood-based immune transcriptomic signature for early lung cancer detection," published in 2025 in npj Precision Oncology

The frequent co-authors collaborating with Bruce A.J. Ponder include:

  • Martin O'Reilly
  • Robert C. Rintoul
  • Joana M. Xavier
  • Ramiro Magno
  • Roslin Russell

Most of their publications appear in journals such as Genome Medicine, Scientific Reports, bioRxiv (Cold Spring Harbor Laboratory), and npj Precision Oncology.

Bruce A.J. Ponder was awarded the Fellowship of the Royal Society, United Kingdom, in 2001.

Best Publications

  • Identification of the breast cancer susceptibility gene BRCA2

    Wooster R;Bignell G;Lancaster J;Swift S

  • Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

    D Ford;D F Easton;M Stratton;S Narod

  • Genome-wide association study identifies novel breast cancer susceptibility loci

    Douglas F. Easton;Karen A. Pooley;Alison M. Dunning;Paul D. P. Pharoah

  • Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13

    Richard Wooster;Susan L. Neuhausen;Jonathan Mangion;Yvette Quirk

  • CONSENSUS: Guidelines for Diagnosis and Therapy of MEN Type 1 and Type 2

    Maria Luisa Brandi;Robert F. Gagel;Alberto Angeli;John P. Bilezikian

  • Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A

    L M Mulligan;J B Kwok;C S Healey;M J Elsdon

  • Degenerate oligonucleotide-primed PCR: General amplification of target DNA by a single degenerate primer

    H. Telenius;N. P. Carter;C. E. Bebb;M. Nordenskjold

  • The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis.

    Charis Eng;Charis Eng;David Clayton;Isabelle Schuffenecker;Gilbert Lenoir

  • Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

    Zhou Songyang;Zhou Songyang;Kermit L. Carraway;Michael J. Eck;Stephen C. Harrison

  • GDNF signalling through the Ret receptor tyrosine kinase

    Pascale Durbec;Camelia V. Marcos-Gutierrez;Carol Kilkenny;Maria Grigoriou

  • Mutations of the RET proto-oncogene in Hirschsprung's disease

    Patrick Edery;Stanislas Lyonnet;Lois M. Mulligan;Anna Pelet

  • Polygenic susceptibility to breast cancer and implications for prevention

    Paul D.P. Pharoah;Antonis Antoniou;Martin Bobrow;Ron L. Zimmern

  • Family history and the risk of breast cancer: A systematic review and meta‐analysis

    Paul D.P. Pharoah;Nicholas E. Day;Stephen Duffy;Douglas F. Easton

  • Oral Contraceptives and the Risk of Hereditary Ovarian Cancer

    S. A. Narod;H. Risch;R. Moslehi;A. Dorum

  • Multifactorial Analysis of Differences Between Sporadic Breast Cancers and Cancers Involving BRCA1 and BRCA2 Mutations

    Sunil R. Lakhani;Jocelyne Jacquemier;John P Sloane;Barry A. Gusterson

  • Involvement of Brca2 in DNA repair.

    Ketan J Patel;Veronica P.C.C Yu;Hyunsook Lee;Anne Corcoran

  • The genetics and genomics of cancer

    Allan Balmain;Joe Gray;Bruce Ponder

  • Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC.

    Lois M. Mulligan;Lois M. Mulligan;Charis Eng;Catherine S. Healey;David Clayton

  • Von Hippel–Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma

    B. R. Seizinger;G. A. Rouleau;L. J. Ozelius;A. H. Lane

  • Erratum: Identification of the breast cancer susceptibility gene BRCA2

    Richard Wooster;Graham Bignell;Jonathan Lancaster;Sally Swift

Frequent Co-Authors

Douglas F. Easton
Douglas F. Easton University of Cambridge
Paul D.P. Pharoah
Paul D.P. Pharoah University of Cambridge
Alison M. Dunning
Alison M. Dunning University of Cambridge
Lois M. Mulligan
Lois M. Mulligan Queen's University
Charis Eng
Charis Eng Cleveland Clinic Lerner College of Medicine
Catherine S. Healey
Catherine S. Healey University of Cambridge
Susan J. Ramus
Susan J. Ramus University of New South Wales
Yusuke Nakamura
Yusuke Nakamura National Institutes of Biomedical Innovation, Health and Nutrition
Alice S. Whittemore
Alice S. Whittemore Stanford University
Robert Luben
Robert Luben University College London

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