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Lois M. Mulligan

Lois M. Mulligan

D-Index & Metrics

Genetics

D-Index
57
Citations
16478
World Ranking
3375
National Ranking
130

Overview

Lois M. Mulligan is affiliated with Queen's University in Canada and has conducted research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work includes a focus on several subfields such as Cell Biology, Molecular Biology, Pulmonary and Respiratory Medicine, Oncology, and Endocrinology, Diabetes and Metabolism.

Their research topics span a range of cellular and molecular processes, including:

  • Cellular transport and secretion
  • Ubiquitin and proteasome pathways
  • Caveolin-1 and cellular processes
  • Microtubule and mitosis dynamics
  • Hormonal regulation and hypertension
  • Adrenal and paraganglionic tumors
  • Lung cancer treatments and mutations

They have published in several scientific venues, with frequent contributions to:

  • Cancer Research
  • eLife
  • Endocrine Related Cancer
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Endocrine Abstracts

Their recent publications include:

  • TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation (2023), published in Cell Reports
  • Selpercatinib: First approved selective RET inhibitor (2023), published in Cell
  • RET isoforms contribute differentially to invasive processes in pancreatic ductal adenocarcinoma (2020), published in Oncogene
  • RET isoform-specific interaction with scaffold protein Ezrin promotes cell migration and chemotaxis in lung adenocarcinoma (2020), published in Lung Cancer
  • Evaluating Cell Membrane Localization and Intracellular Transport of Proteins by Biotinylation (2022), published in Methods in Molecular Biology

Frequent co-authors collaborating with Lois M. Mulligan are:

  • Brandy D. Hyndman
  • Timothy J. Walker
  • Eduardo Reyes-Alvarez
  • Costin N. Antonescu
  • Qianjin Guo

Best Publications

  • Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A

    L M Mulligan;J B Kwok;C S Healey;M J Elsdon

  • The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis.

    Charis Eng;Charis Eng;David Clayton;Isabelle Schuffenecker;Gilbert Lenoir

  • Mutations of the RET proto-oncogene in Hirschsprung's disease

    Patrick Edery;Stanislas Lyonnet;Lois M. Mulligan;Anna Pelet

  • Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC.

    Lois M. Mulligan;Lois M. Mulligan;Charis Eng;Catherine S. Healey;David Clayton

  • Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours

    C Eng;D P Smith;L M Mulligan;M A Nagai

  • RET revisited: expanding the oncogenic portfolio

    Lois M. Mulligan

  • Immunohistochemical Evidence of Loss of PTEN Expression in Primary Ductal Adenocarcinomas of the Breast

    Aurel Perren;Liang Ping Weng;Alexander H. Boag;Ulricke Ziebold

  • Diversity of RET proto-oncogene mutations in familial and sporadic Hirschsprung disease

    Tania Attié;Anna Pelet;Patrick Edery;Charis Eng;Charis Eng

  • Mechanisms of p53 loss in human sarcomas.

    Lois M. Mulligan;Greg J. Matlashewski;Heidi J. Scrable;Webster K. Cavenee

  • Genotype-phenotype correlation in multiple endocrine neoplasia type 2: report of the International RET Mutation Consortium.

    L. M. Mulligan;D. J. Marsh;B. G. Robinson;I. Schuffenecker

  • A novel point mutation in the tyrosine kinase domain of the RET proto-oncogene in sporadic medullary thyroid carcinoma and in a family with FMTC

    Charis Eng;D. P. Smith;L. M. Mulligan;C. S. Healey

  • Multiple endocrine neoplasia type 2 and RET : from neoplasia to neurogenesis

    Jordan R Hansford;Lois M Mulligan

  • Analysis of PTEN and the 10q23 region in primary prostate carcinomas.

    Harriet E Feilotter;Maria A Nagai;Alexander H Boag;Charis Eng

  • Diverse phenotypes associated with exon 10 mutations of the RET proto-oncogene

    Lois M. Mulligan;Charts Eng;Tanla Attlé;Stanislas Lyonnet

  • Germline dinucleotide mutation in codon 883 of the RET proto-oncogene in multiple endocrine neoplasia type 2B without codon 918 mutation

    Oliver Gimm;Debbie J. Marsh;Scott D. Andrew;Andrea Frilling

  • Mutations of the RET proto‐oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumours, and Hirschsprung disease

    Charis Eng;Lois M. Mulligan

  • Characterization of RET proto-oncogene 3' splicing variants and polyadenylation sites: a novel C-terminus for RET.

    Shirley M. Myers;Charis Eng;Charis Eng;Bruce A J Ponder;Lois M. Mulligan

  • Heterogeneous Mutation of the RET Proto-oncogene in Subpopulations of Medullary Thyroid Carcinoma

    Charis Eng;Lois M. Mulligan;Catherine S. Healey;Carol Houghton

  • Low frequency of germline mutations in the RET proto-oncogene in patients with apparently sporadic medullary thyroid carcinoma.

    Charls Eng;Lois M. Mulligan;Lois M. Mulligan;Darrin P. Smith;Catherine S. Healey

  • Mutation of the RET protooncogene in sporadic medullary thyroid carcinoma

    Charis Eng;Charis Eng;Lois M. Mulligan;Lois M. Mulligan;Darrin P. Smith;Catherine S. Healey

Frequent Co-Authors

Charis Eng
Charis Eng Cleveland Clinic Lerner College of Medicine
Bruce A.J. Ponder
Bruce A.J. Ponder University of Cambridge
Catherine S. Healey
Catherine S. Healey University of Cambridge
Bruce G. Robinson
Bruce G. Robinson University of Sydney
Bradley N. White
Bradley N. White Trent University
Stanislas Lyonnet
Stanislas Lyonnet Université Paris Cité
Patricia L. M. Dahia
Patricia L. M. Dahia The University of Texas Health Science Center at San Antonio
Alan Tunnacliffe
Alan Tunnacliffe University of Cambridge
John B.J. Kwok
John B.J. Kwok University of Sydney

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