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Neuroscience

D-Index
98
Citations
32959
World Ranking
804
National Ranking
441

Research.com Recognitions

  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jeffrey L. Noebels is affiliated with Baylor College of Medicine in the United States. Their research primarily spans diverse areas within neuroscience, biochemistry, genetics, molecular biology, and medicine, with a publication record reflecting a multidisciplinary approach. The scientist's work is distributed across several subfields, including cellular and molecular neuroscience, genetics, molecular biology, psychiatry and mental health, and cognitive neuroscience.

Their main research topics encompass neuroscience and neuropharmacology, epilepsy research and treatment, ion channel regulation and function, genetics and neurodevelopmental disorders, glioma diagnosis and treatment, neural dynamics and brain function, and genomics and rare diseases.

Among the frequent publication venues where their research appears are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Epilepsy Currents
  • Nature
  • eLife
  • Epilepsia

Recent papers authored include:

  • PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis, 2020, Nature
  • Remote neuronal activity drives glioma progression through SEMA4F, 2023, Nature
  • Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model, 2020, Journal of Clinical Investigation
  • Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation, 2023, Neuron
  • Kcnq2/Kv7.2 controls the threshold and bi-hemispheric symmetry of cortical spreading depolarization, 2021, Brain

Frequent collaborators include:

  • Isamu Aiba
  • Benjamin Deneen
  • Yao Ning
  • Brittney Lozzi
  • Emmet Huang-Hobbs

Jeffrey L. Noebels was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2017.

Best Publications

  • Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease

    Jorge J. Palop;Jeannie Chin;Erik D. Roberson;Jun Wang

  • Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

    Hsiao Tuan Chao;Hongmei Chen;Rodney C. Samaco;Mingshan Xue;Mingshan Xue

  • MUTATION OF THE ANGELMAN UBIQUITIN LIGASE IN MICE CAUSES INCREASED CYTOPLASMIC P53 AND DEFICITS OF CONTEXTUAL LEARNING AND LONG-TERM POTENTIATION

    Y. H. Jiang;D. Armstrong;U. Albrecht;C. M. Atkins

  • Mice with Truncated MeCP2 Recapitulate Many Rett Syndrome Features and Display Hyperacetylation of Histone H3

    Mona D. Shahbazian;Juan I. Young;Lisa A. Yuva-Paylor;Corinne M. Spencer

  • Amyloid-β/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

    Erik D. Roberson;Brian Halabisky;Jong W. Yoo;Jinghua Yao

  • Mild overexpression of MeCP2 causes a progressive neurological disorder in mice

    Ann L. Collins;Jonathan M. Levenson;Alexander P. Vilaythong;Ronald Richman

  • Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10

    Tohru Matsuura;Tohru Matsuura;Takanori Yamagata;Daniel L. Burgess;Astrid Rasmussen

  • Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy.

    Inma Cobos;Maria Elisa Calcagnotto;Alex J Vilaythong;Myo T Thwin

  • Jasper's basic mechanisms of the epilepsies

    Jeffrey L Noebels;Massimo Avoli;Michael A Rogawski;Richard W Olsen

  • Mutation of the Ca2+ Channel β Subunit Gene Cchb4 Is Associated with Ataxia and Seizures in the Lethargic (lh) Mouse

    Daniel L Burgess;Julie M Jones;Miriam H Meisler;Jeffrey L Noebels

  • Identification of diverse astrocyte populations and their malignant analogs.

    Chia-Ching John Lin;Kwanha Yu;Asante Hatcher;Teng-Wei Huang

  • Mutation in AP-3 δ in the mocha Mouse Links Endosomal Transport to Storage Deficiency in Platelets, Melanosomes, and Synaptic Vesicles

    Prameela Kantheti;Xiaoxi Qiao;Maria E Diaz;Andrew A Peden

  • Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3

    Rebecca P. Seal;Omar Akil;Eunyoung Yi;Christopher M. Weber

  • BK channel β4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures

    Robert Brenner;Qing H Chen;Alex Vilaythong;Glenn M Toney

  • Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models

    Isamu Aiba;Jeffrey L. Noebels

  • Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunction.

    Elizabeth M. Powell;Daniel B. Campbell;Gregg D. Stanwood;Caleb Davis

  • Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.

    S F Kash;R S Johnson;L H Tecott;J L Noebels

  • Silent hippocampal seizures and spikes identified by foramen ovale electrodes in Alzheimer's disease.

    Alice D Lam;Gina Deck;Alica Goldman;Emad N Eskandar

  • Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy.

    Min Liu;Samuel J. Pleasure;Abigail E. Collins;Jeffrey L. Noebels

  • Arrhythmia in Heart and Brain: KCNQ1 Mutations Link Epilepsy and Sudden Unexplained Death

    A. M. Goldman;E. Glasscock;J. Yoo;T. T. Chen

  • Progressive ataxia, myoclonic epilepsy and cerebellar apoptosis in cystatin B-deficient mice

    Len A. Pennacchio;Donna M. Bouley;Kay M. Higgins;Matthew P. Scott

  • Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering.

    Jeffrey L. Noebels;Richard L. Sidman

Frequent Co-Authors

Michael A. Rogawski
Michael A. Rogawski University of California, Davis
Antonio V. Delgado-Escueta
Antonio V. Delgado-Escueta University of California, Los Angeles
Robert B. Darnell
Robert B. Darnell Rockefeller University
Massimo Avoli
Massimo Avoli McGill University
Stefan Herlitze
Stefan Herlitze Ruhr University Bochum
Richard W. Olsen
Richard W. Olsen University of California, Los Angeles
Huda Y. Zoghbi
Huda Y. Zoghbi Baylor College of Medicine
Daniel H. Lowenstein
Daniel H. Lowenstein University of California, San Francisco
David A. Prince
David A. Prince Stanford University
Arthur L. Beaudet
Arthur L. Beaudet Baylor College of Medicine

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