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Genetics

D-Index
73
Citations
33197
World Ranking
2006
National Ranking
914

Overview

Wayne N. Frankel is affiliated with Columbia University in the United States and works primarily within the fields of Neuroscience, Medicine, and Biochemistry, Genetics, and Molecular Biology. Their research focuses predominantly on cellular and molecular neuroscience, psychiatry and mental health, and genetics.

The scientist's recent scholarly contributions include investigations into neurodevelopmental disorders and epilepsy. Two notable papers published by Wayne N. Frankel are:

  • "Impaired axon initial segment structure and function in a model of ARHGEF9 developmental and epileptic encephalopathy" (2024), published in Proceedings of the National Academy of Sciences
  • "Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy" (2025), published in Brain

These publications highlight a research interest in the molecular and cellular mechanisms underlying epilepsy and neurodevelopmental genetic disorders.

Wayne N. Frankel frequently collaborates with other researchers, including:

  • Jia Jie Teoh
  • Wanqi Wang
  • Damian J. Williams
  • Divyalakshmi Soundararajan
  • Cathleen Lutz

The primary publication venues for their work are the journal Brain and the Proceedings of the National Academy of Sciences, reflecting a focus on neuroscience and neurological research.

Main topics covered by Wayne N. Frankel's research comprise neuroscience and neuropharmacology research, epilepsy research and treatment, and genetics and neurodevelopmental disorders.

Best Publications

  • Initial sequencing and comparative analysis of the mouse genome.

    Robert H. Waterston;Kerstin Lindblad-Toh;Ewan Birney;Jane Rogers

  • The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity

    L. de Lecea;T. S. Kilduff;C. Peyron;X.-B. Gao

  • Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies.

    Jacqueline N. Crawley;John K. Belknap;Allan Collins;John C. Crabbe

  • TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells*

    Brian R. Wong;Jaerang Rho;Joseph Arron;Elizabeth Robinson

  • Absence epilepsy in tottering mutant mice is associated with calcium channel defects

    Colin F Fletcher;Cathleen M Lutz;T.Norene O'Sullivan;John D Shaughnessy

  • The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit.

    Verity A. Letts;Ricardo Felix;Gloria H. Biddlecome;Jyothi Arikkath

  • The harlequin mouse mutation downregulates apoptosis-inducing factor

    Jeffrey A. Klein;Chantal M. Longo-Guess;Marlies P. Rossmann;Kevin L. Seburn

  • Maps from two interspecific backcross DNA panels available as a community genetic mapping resource

    L. B. Rowe;J. H. Nadeau;R. Turner;W. N. Frankel

  • Disruption of the nuclear hormone receptor RORα in staggerer mice

    Bruce A. Hamilton;Wayne N. Frankel;Anne W. Kerrebrock;Trevor L. Hawkins

  • An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

    Hye-Won Shin;Mitsuko Hayashi;Savvas Christoforidis;Sandra Lacas-Gervais

  • Who's afraid of epistasis?

    Wayne N. Frankel;Nicholas J. Schork;Nicholas J. Schork

  • Ducky Mouse Phenotype of Epilepsy and Ataxia Is Associated with Mutations in the Cacna2d2 Gene and Decreased Calcium Channel Current in Cerebellar Purkinje Cells

    J Barclay;N Balaguero;M Mione;SL Ackerman

  • Linkage of Mls genes to endogenous mammary tumour viruses of inbred mice.

    Wayne N. Frankel;Christine Rudy;John M. Coffin;Brigitte T. Huber

  • The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries

    Kenro Kusumi;Eileen S. Sun;Anne W. Kerrebrock;Roderick T. Bronson

  • SODIUM/HYDROGEN EXCHANGER GENE DEFECT IN SLOW-WAVE EPILEPSY MUTANT MICE

    Gregory A. Cox;Cathleen M. Lutz;Chao Ling Yang;Daniel Biemesderfer

  • The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs.

    Joseph H. Nadeau;Wayne N. Frankel

  • KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

    Rachel L. Wolfson;Lynne Chantranupong;Gregory A. Wyant;Xin Gu

  • Transcription profiling of inner ears from Pou4f3ddl/ddl identifies Gfi1 as a target of the Pou4f3 deafness gene

    Ronna Hertzano;Ronna Hertzano;Mireille Montcouquiol;Sharon Rashi-Elkeles;Rani Elkon

  • Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice.

    Wesley G. Beamer;Kathryn L. Shultz;Gary A. Churchill;Wayne N. Frankel

  • The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit [see comments]

    V A Letts;R Felix;G H Biddlecome;J Arikkath

Frequent Co-Authors

John M. Coffin
John M. Coffin Tufts University
David Goldstein
David Goldstein University of New South Wales
Jonathan P. Stoye
Jonathan P. Stoye The Francis Crick Institute
Slavé Petrovski
Slavé Petrovski AstraZeneca (United Kingdom)
Eric S. Lander
Eric S. Lander Broad Institute
Liane B. Russell
Liane B. Russell Oak Ridge National Laboratory
Joseph H. Nadeau
Joseph H. Nadeau Pacific Northwest Diabetes Research Institute
Dan Goldowitz
Dan Goldowitz University of British Columbia
Joseph S. Takahashi
Joseph S. Takahashi The University of Texas Southwestern Medical Center
H. Steve White
H. Steve White University of Washington

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