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Genetics

D-Index
73
Citations
23298
World Ranking
2028
National Ranking
927

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Joseph H. Nadeau is affiliated with the Pacific Northwest Diabetes Research Institute in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with 23 publications in these areas. The scientist's work encompasses several subfields including molecular biology, epidemiology, physiology, cancer research, and aging.

Their main research topics include adipose tissue and metabolism, single-cell and spatial transcriptomics, RNA modifications and cancer, genetics, aging, and longevity in model organisms, Parkinson's disease mechanisms and treatments, epigenetics and DNA methylation, and liver disease diagnosis and treatment.

Joseph H. Nadeau has published in various scientific journals, frequently contributing to the following venues:

  • WIREs Mechanisms of Disease
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Investigation
  • Mammalian Genome
  • Nature Metabolism

Frequent co-authors include Justus Anumonwo, Helen M. Byrne, Roxana Deleanu, Gabriel Haddad, and Cui Hua Liu, each having collaborated on seven publications.

Significant recent papers by Joseph H. Nadeau are:

  • Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer, 2020, Journal of Clinical Investigation
  • Independent phenotypic plasticity axes define distinct obesity sub-types, 2022, Nature Metabolism
  • Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging, 2020, Frontiers in Genetics
  • Quantitative trait locus mapping identifies a locus linked to striatal dopamine and points to collagen IV alpha-6 chain as a novel regulator of striatal axonal branching in mice, 2021, Genes Brain & Behavior
  • Genetically-biased fertilization in APOBEC1 complementation factor (A1cf) mutant mice, 2022, Scientific Reports

Joseph H. Nadeau was awarded the status of Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • Missing heritability and strategies for finding the underlying causes of complex disease

    Evan E. Eichler;Jonathan Flint;Greg Gibson;Augustine Kong

  • The Collaborative Cross, a community resource for the genetic analysis of complex traits

    Gary A. Churchill;David C. Airey;Hooman Allayee;Joe M. Angel

  • Finding Genes That Underlie Complex Traits

    Anne M. Glazier;Joseph H. Nadeau;Timothy J. Aitman

  • Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function

    Linda S. Robbins;Joseph H. Nadeau;Kenneth R. Johnson;Michele A. Kelly

  • Lengths of chromosomal segments conserved since divergence of man and mouse.

    Joseph H. Nadeau;Benjamin A. Taylor

  • Modifier genes in mice and humans.

    Joseph H. Nadeau

  • A genetic linkage map of the mouse: current applications and future prospects

    Neal G. Copeland;Nancy A. Jenkins;Debra J. Gilbert;Janan T. Eppig

  • Maps from two interspecific backcross DNA panels available as a community genetic mapping resource

    L. B. Rowe;J. H. Nadeau;R. Turner;W. N. Frankel

  • Analysing complex genetic traits with chromosome substitution strains

    Joseph H. Nadeau;Jonathan B. Singer;Angabin Matin;Eric S. Lander

  • Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor

    Richard Rozmahel;Michael Wilschanski;Angabin Matin;Suzanne Plyte

  • The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours

    Kirsten K. Youngren;Douglas Coveney;Xiaoning Peng;Chitralekha Bhattacharya

  • Genetic Dissection of Complex Traits with Chromosome Substitution Strains of Mice

    Jonathan B. Singer;Annie E. Hill;Lindsay C. Burrage;Keith R. Olszens

  • COMPARABLE RATES OF GENE LOSS AND FUNCTIONAL DIVERGENCE AFTER GENOME DUPLICATIONS EARLY IN VERTEBRATE EVOLUTION

    Joseph H. Nadeau;David Sankoff

  • Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis

    Haifeng Shao;Lindsay C. Burrage;David S. Sinasac;Annie E. Hill

  • The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs.

    Joseph H. Nadeau;Wayne N. Frankel

  • Maps of linkage and synteny homologies between mouse and man.

    Joseph H. Nadeau

  • Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain

    David W. Threadgill;David W. Threadgill;Delia Yee;Argabin Matin;Joseph H. Nadeau

  • Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene.

    Jennifer S. Colvin;Benjamin Feldman;Joseph H. Nadeau;Mitchell Goldfarb

  • Sequence interpretation. Functional annotation of mouse genome sequences.

    J. H. Nadeau;R. Balling;G. Barsh;D. Beier

  • Comparative Genomics: "Empirical And Analytical Approaches To Gene Order Dynamics, Map Alignment And The Evolution Of Gene Families"

    David Sankoff;Joseph H. Nadeau

Frequent Co-Authors

David Sankoff
David Sankoff University of Ottawa
Eric S. Lander
Eric S. Lander Broad Institute
Shankar Subramaniam
Shankar Subramaniam University of California, San Diego
Huntington F. Willard
Huntington F. Willard Duke University
David W. Threadgill
David W. Threadgill Texas A&M University
Gary A. Churchill
Gary A. Churchill The Jackson Laboratory
Pamela Sklar
Pamela Sklar Icahn School of Medicine at Mount Sinai
Blanche Capel
Blanche Capel Duke University
Monica J. Justice
Monica J. Justice Hospital for Sick Children
Wayne N. Frankel
Wayne N. Frankel Columbia University

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