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Genetics

D-Index
63
Citations
13911
World Ranking
2893
National Ranking
102

Research.com Recognitions

  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Monica J. Justice is affiliated with the Hospital for Sick Children in Canada. Their research spans a variety of topics within biochemistry, genetics, molecular biology, and medicine, with a particular focus on molecular biology and genetics as primary subfields. Their work involves areas such as genetics and neurodevelopmental disorders, RNA modifications and cancer, epigenetics and DNA methylation, ubiquitin and proteasome pathways, cancer-related gene regulation, peptidase inhibition and analysis, and chromatin remodeling and cancer.

The scientist has published extensively, with notable recent papers including:

  • A resource of targeted mutant mouse lines for 5,061 genes, 2021, Nature Genetics
  • CyTOF: An Emerging Technology for Single-Cell Proteomics in the Mouse, 2021, Current Protocols
  • Suppressor mutations in Mecp2-null mice implicate the DNA damage response in Rett syndrome pathology, 2020, Genome Research
  • Sex matters in preclinical research, 2024, Disease Models & Mechanisms
  • A new murine Rpl5 ( uL18 ) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia, 2021, Blood Advances

Their publications frequently appear in the following venues:

  • American Journal of Respiratory and Critical Care Medicine
  • Disease Models & Mechanisms
  • Human Molecular Genetics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Genetics

Monica J. Justice collaborates regularly with several co-authors, including:

  • Christine Taylor
  • Joanna M. Poczobutt
  • I. Petrache
  • T. Rivera
  • Julie Ruston

Their professional recognition includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2016.

Best Publications

  • High-throughput discovery of novel developmental phenotypes

    Mary E. Dickinson;Ann M. Flenniken;Xiao Ji;Lydia Teboul

  • A Twist Code Determines the Onset of Osteoblast Differentiation

    Peter Bialek;Britt Kern;Xiangli Yang;Marijke Schrock

  • Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail.

    Z Kibar;K J Vogan;N Groulx;M J Justice

  • The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins.

    Thomas A. Ebersole;Thomas A. Ebersole;Qi Chen;Qi Chen;Monica J. Justice;Monica J. Justice;Karen Artzt

  • Gene defect in ectodermal dysplasia implicates a death domain adapter in development.

    Denis J. Headon;Stephanie A. Emmal;Betsy M. Ferguson;Abigail S. Tucker

  • Genetic Dissection of Complex Traits with Chromosome Substitution Strains of Mice

    Jonathan B. Singer;Annie E. Hill;Lindsay C. Burrage;Keith R. Olszens

  • Using the mouse to model human disease: increasing validity and reproducibility

    Monica J. Justice;Paraminder Dhillon

  • Prevalence of sexual dimorphism in mammalian phenotypic traits

    Natasha A. Karp;Natasha A. Karp;Jeremy Mason;Arthur L. Beaudet;Yoav Benjamini

  • A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome

    Christie M Buchovecky;Stephen D Turley;Hannah M Brown;Hannah M Brown;Stephanie M Kyle

  • Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.

    Bruce J. Herron;Weining Lu;Cherie Rao;Shanming Liu

  • Functional genetic analysis of mouse chromosome 11

    Benjamin T. Kile;Kathryn E. Hentges;Amander T. Clark;Hisashi Nakamura

  • Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome

    Jonathan L. Tobin;Matt Di Franco;Erica Eichers;Helen May-Simera

  • Identification of the murine beige gene by YAC complementation and positional cloning

    Charles M. Perou;Karen J. Moore;Deborah L. Nagle;Donald J. Misumi

  • Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium

    Terrence F Meehan;Nathalie Conte;David B West;Julius O Jacobsen

  • Preclinical research in Rett syndrome: Setting the foundation for translational success

    David M. Katz;Joanne E. Berger-Sweeney;James H. Eubanks;Monica J. Justice

  • Effects of ENU dosage on mouse strains.

    Monica J. Justice;Don A. Carpenter;Jack Favor;Angelika Neuhauser-Klaus

  • The mutagenic action of N-ethyl-N-nitrosourea in the mouse.

    J.K. Noveroske;J.S. Weber;M.J. Justice

  • Sequence interpretation. Functional annotation of mouse genome sequences.

    J. H. Nadeau;R. Balling;G. Barsh;D. Beier

  • Overexpression of Eg5 causes genomic instability and tumor formation in mice.

    Andrew Castillo;Herbert C. Morse;Virginia L. Godfrey;Rizwan Naeem

  • Rett syndrome: a neurological disorder with metabolic components.

    Stephanie M. Kyle;Neeti Vashi;Monica J. Justice

Frequent Co-Authors

Allan Bradley
Allan Bradley University of Cambridge
Arthur L. Beaudet
Arthur L. Beaudet Baylor College of Medicine
Martin Hrabé de Angelis
Martin Hrabé de Angelis Technical University of Munich
Colin McKerlie
Colin McKerlie Hospital for Sick Children
David J. Adams
David J. Adams Wellcome Sanger Institute
Kevin C K Lloyd
Kevin C K Lloyd University of California, Davis
Yann Herault
Yann Herault Institute of Genetics and Molecular and Cellular Biology
James R. Lupski
James R. Lupski Baylor College of Medicine
Steve D.M. Brown
Steve D.M. Brown Medical Research Council
Karen P. Steel
Karen P. Steel King's College London

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