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D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
25390
World Ranking
4974
National Ranking
2391

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2011 - Fellow of the American Academy of Arts and Sciences
  • 2008 - Member of the National Academy of Sciences
  • 1995 - W. Alden Spencer Award, College of Physicians and Surgeons
  • 1986 - Fellow of Alfred P. Sloan Foundation

Overview

Richard W. Aldrich is affiliated with The University of Texas at Austin in the United States. Their research focuses primarily on the field of Biochemistry, Genetics and Molecular Biology with a specific emphasis on Molecular Biology and Cellular and Molecular Neuroscience.

The scientist's main topics of work include:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Pharmacological receptor mechanisms and effects
  • Nicotinic acetylcholine receptors study
  • Ion channels and receptors
  • Receptor mechanisms and signaling
  • Mass spectrometry techniques and applications

Recent publications by Richard W. Aldrich include the following papers:

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels, 2021, British Journal of Pharmacology
  • The Concise Guide to PHARMACOLOGY 2023/24: Ion channels, 2023, British Journal of Pharmacology
  • Implications of a temperature-dependent heat capacity for temperature-gated ion channels, 2023, Proceedings of the National Academy of Sciences
  • Structural basis of cytoplasmic NaV1.5 and NaV1.4 regulation, 2020, The Journal of General Physiology
  • Mapping Functional Protein Neighborhoods in the Mouse Brain, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Aldrich include:

  • Stephan Grissmer
  • Leonard K. Kaczmarek
  • Heike Wulff
  • D. Brent Halling
  • Frank Yeh

Publications by Aldrich appear mainly in these venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • IUPHAR/BPS Guide to Pharmacology CITE
  • British Journal of Pharmacology
  • Biophysical Journal
  • Proceedings of the National Academy of Sciences

Throughout their career, Aldrich has received several recognitions which include:

  • Member of the National Academy of Sciences (2008)
  • Fellow of the American Academy of Arts and Sciences (2011)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2014)
  • W. Alden Spencer Award, College of Physicians and Surgeons (1995)
  • Fellow of Alfred P. Sloan Foundation (1986)

Best Publications

  • Biophysical and molecular mechanisms of shaker potassium channel inactivation

    Toshinori Hoshi;William N. Zagotta;Richard W. Aldrich

  • International Union of Pharmacology. LIII. Nomenclature and Molecular Relationships of Voltage-Gated Potassium Channels

    Aguan D. Wei;George A. Gutman;Richard W Aldrich;K. George Chandy

  • Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB

    William N. Zagotta;Toshinori Hoshi;Richard W. Aldrich

  • Vasoregulation by the β1 subunit of the calcium-activated potassium channel

    Robert Brenner;Guillermo J. Peréz;Adrian D. Bonev;Delrae M. Eckman

  • Two types of inactivation in Shaker K+ channels: Effects of alterations in the carboxy-terminal region

    Toshinori Hoshi;William N. Zagotta;Richard W. Aldrich

  • A reinterpretation of mammalian sodium channel gating based on single channel recording

    Richard W Aldrich;D. P. Corey;C. F. Stevens

  • Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels.

    J. Lopezbarneo;T. Hoshi;S. H. Heinemann;R. W. Aldrich

  • Shaker potassium channel gating. III: Evaluation of kinetic models for activation

    William N. Zagotta;Toshinori Hoshi;Toshinori Hoshi;Richard W Aldrich

  • Local potassium signaling couples neuronal activity to vasodilation in the brain.

    Jessica A Filosa;Jessica A Filosa;Adrian D Bonev;Stephen V Straub;Andrea L Meredith;Andrea L Meredith

  • Cloning and Functional Characterization of Novel Large Conductance Calcium-activated Potassium Channel β Subunits, hKCNMB3 and hKCNMB4

    Robert Brenner;Tim J. Jegla;Alan Wickenden;Yi Liu

  • Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels.

    Kathleen L. Choi;Richard W. Aldrich;Gary Yellen;Gary Yellen

  • Coupling between Voltage Sensor Activation, Ca2+ Binding and Channel Opening in Large Conductance (BK) Potassium Channels

    Frank T. Horrigan;Richard W. Aldrich

  • Expression cloning of a rat B2 bradykinin receptor.

    Adrienne E. McEachern;Earl R. Shelton;Sunil Bhakta;Rena Obernolte

  • BK channel β4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures

    Robert Brenner;Qing H Chen;Alex Vilaythong;Glenn M Toney

  • Overactive Bladder and Incontinence in the Absence of the BK Large Conductance Ca2+-activated K+ Channel

    Andrea L. Meredith;Kevin S. Thorneloe;Matthias E. Werner;Mark T. Nelson

  • Allosteric Voltage Gating of Potassium Channels I: Mslo Ionic Currents in the Absence of Ca2+

    Frank T. Horrigan;Jianmin Cui;Richard W. Aldrich

  • Shaker potassium channel gating. II: Transitions in the activation pathway.

    W N Zagotta;T Hoshi;J Dittman;R W Aldrich

  • Voltage-dependent gating of Shaker A-type potassium channels in Drosophila muscle.

    W N Zagotta;R W Aldrich

  • Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction

    Hélène Girouard;Adrian D. Bonev;Rachael M. Hannah;Andrea Meredith

  • Mutations in the S4 Region Isolate the Final Voltage-dependent Cooperative Step in Potassium Channel Activation

    Jennifer L. Ledwell;Richard W. Aldrich

Frequent Co-Authors

Toshinori Hoshi
Toshinori Hoshi University of Pennsylvania
Mark Nelson
Mark Nelson University of Vermont
Anthony A. Fodor
Anthony A. Fodor University of North Carolina at Charlotte
James S. Trimmer
James S. Trimmer University of California, Davis
Heike Wulff
Heike Wulff University of California, Davis
Charles F. Stevens
Charles F. Stevens Salk Institute for Biological Studies
Diane K. O'Dowd
Diane K. O'Dowd University of California, Irvine
Richard W. Tsien
Richard W. Tsien New York University
Joseph S. Takahashi
Joseph S. Takahashi The University of Texas Southwestern Medical Center
Michael S. Brainard
Michael S. Brainard University of California, San Francisco

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