World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
30822
World Ranking
17801
National Ranking
7283

Overview

Shengyun Fang is affiliated with the University of Maryland, Baltimore in the United States. Their research primarily lies within the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these domains, their work covers subfields including Molecular Biology, Cell Biology, Immunology, Oncology, and Pulmonary and Respiratory Medicine.

The scientist's research topics encompass various areas related to cellular and molecular mechanisms. These topics include:

  • Endoplasmic Reticulum Stress and Disease
  • Ubiquitin and proteasome pathways
  • Cancer-related Molecular Pathways
  • Prostate Cancer Treatment and Research
  • Protein Degradation and Inhibitors
  • Autophagy in Disease and Therapy
  • Heat shock proteins research

Some of Shengyun Fang's recent papers include:

  • "Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes" (2023), published in Nature Communications
  • "The Role of Crosstalk between AR3 and E2F1 in Drug Resistance in Prostate Cancer Cells" (2020), published in Cells
  • "A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase" (2022), published in Molecular Biology of the Cell
  • "Regulation of p27 (Kip1) by Ubiquitin E3 Ligase RNF6" (2022), published in Pharmaceutics
  • "XBP1 variant 1 promotes mitosis of cancer cells involving upregulation of the polyglutamylase TTLL6" (2022), published in Human Molecular Genetics

The frequent co-authors with whom Shengyun Fang has collaborated include:

  • Yongwang Zhong
  • Wenjing Yan
  • Shaojun Du
  • Ganesha Rai
  • Mark J. Henderson

Publication venues where Shengyun Fang's work appears frequently include:

  • Nature Communications
  • Pharmaceutics
  • Molecular Biology of the Cell
  • Cells
  • Human Molecular Genetics

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

    Kevin L. Lorick;Jane P. Jensen;Shengyun Fang;Albert M. Ong

  • Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53

    Shengyun Fang;Jane P. Jensen;Robert L. Ludwig;Karen H. Vousden

  • Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli.

    Yili Yang;Shengyun Fang;Jane P. Jensen;Allan M. Weissman

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • SINAT5 promotes ubiquitin-related degradation of NAC1 to attenuate auxin signals

    Qi Xie;Hui-Shan Guo;Geza Dallman;Shengyun Fang

  • The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

    Shengyun Fang;Marco Ferrone;Cuihong Yang;Jane P. Jensen

  • A field guide to ubiquitylation.

    S Fang;A M Weissman

  • Glycogen synthase kinase 3β (GSK3β) mediates 6-hydroxydopamine-induced neuronal death

    Gang Chen;Kimberly A. Bower;Cuiling Ma;Shengyun Fang

  • Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death.

    Andria Apostolou;Yuxian Shen;Yan Liang;Jun Luo

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover.

    Shan Xu;Guihong Peng;Yang Wang;Shengyun Fang

  • Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination.

    Kexin Xu;Hermela Shimelis;Douglas E. Linn;Richeng Jiang

  • AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation.

    Xiaoyan Zhong;Yuxian Shen;Petek Ballar;Andria Apostolou

  • Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy

    Cara Rothenberg;Deepa Srinivasan;Leann Mah;Susmita Kaushik

  • Selective Inhibition of Endoplasmic Reticulum-associated Degradation Rescues ΔF508-Cystic Fibrosis Transmembrane Regulator and Suppresses Interleukin-8 Levels: THERAPEUTIC IMPLICATIONS *

    Neeraj Vij;Shengyun Fang;Pamela L. Zeitlin

  • Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer

    Jun Zhang;Yixing Jiang;Zhiliang Jia;Qiang Li

  • WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation.

    Alessandra Magnifico;Seth Ettenberg;Cuihong Yang;Jennifer Mariano

  • RING finger ubiquitin protein ligases: implications for tumorigenesis, metastasis and for molecular targets in cancer

    Shengyun Fang;Kevin L. Lorick;Jane P. Jensen;Allan M. Weissman

Frequent Co-Authors

James Christensen
James Christensen Pfizer (United States)
Allan M. Weissman
Allan M. Weissman National Institutes of Health
Evelina Gatti
Evelina Gatti Aix-Marseille University
Sergio Lavandero
Sergio Lavandero University of Chile
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Leonidas C. Platanias
Leonidas C. Platanias Northwestern University
Ralph A. Nixon
Ralph A. Nixon Nathan Kline Institute for Psychiatric Research
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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