D-Index & Metrics Best Publications
Biology and Biochemistry
Israel
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 112 Citations 68,346 310 World Ranking 596 National Ranking 4

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Israel Leader Award

2022 - Research.com Biology and Biochemistry in Israel Leader Award

2016 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics

2013 - Fellow, National Academy of Inventors

2009 - Member of Academia Europaea

2009 - Centenary Prize, Royal Society of Chemistry (UK)

2008 - Fellow of the American Academy of Arts and Sciences

2008 - Member of the National Academy of Medicine (NAM)

2007 - Member of the National Academy of Sciences

2004 - Nobel Prize for the discovery of ubiquitin-mediated protein degradation

2004 - Member of the European Academy of Sciences

2000 - Albert Lasker Award for Basic Medical Research, Lasker Foundation

Member of the European Academy of Sciences and Arts

Member of the Association of American Physicians

Foreign Member, Chinese Academy of Sciences

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

Aaron Ciechanover focuses on Ubiquitin, Biochemistry, Cell biology, Ubiquitin ligase and Proteasome. His research integrates issues of Lysosome, Protein degradation, Molecular biology, Affinity chromatography and Signal transduction in his study of Ubiquitin. His work in the fields of Proteolysis, Ubiquitins, Cell cycle and Ubiquitin-activating enzyme overlaps with other areas such as Covalent bond.

His Cell biology research integrates issues from Receptor, F-box protein, DNA repair and Monoubiquitination. His Ubiquitin ligase research is multidisciplinary, incorporating perspectives in Residue, Histone and DNA ligase. Protease is closely connected to Antigen processing in his research, which is encompassed under the umbrella topic of Proteasome.

His most cited work include:

  • The Ubiquitin System (7191 citations)
  • The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction (3307 citations)
  • The ubiquitin-proteasome proteolytic pathway (1570 citations)

What are the main themes of his work throughout his whole career to date?

Aaron Ciechanover mainly focuses on Ubiquitin, Cell biology, Biochemistry, Proteasome and Ubiquitin ligase. His research in Ubiquitin intersects with topics in Cell cycle, DNA ligase, Protein degradation and Proteolysis. His Cell biology research is multidisciplinary, relying on both Autophagy, Molecular biology, Transcription factor and Lysosome.

His studies in Ubiquitins, Enzyme, Ubiquitin-activating enzyme, Protease and Peptide sequence are all subfields of Biochemistry research. Aaron Ciechanover works mostly in the field of Proteasome, limiting it down to concerns involving Intracellular and, occasionally, RNA. Aaron Ciechanover has included themes like Deubiquitinating enzyme, Lysine, NF-κB, Phosphorylation and Protein structure in his Ubiquitin ligase study.

He most often published in these fields:

  • Ubiquitin (78.81%)
  • Cell biology (62.71%)
  • Biochemistry (47.74%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (62.71%)
  • Ubiquitin (78.81%)
  • Proteasome (41.24%)

In recent papers he was focusing on the following fields of study:

Aaron Ciechanover spends much of his time researching Cell biology, Ubiquitin, Proteasome, Ubiquitin ligase and Protein degradation. His Cell biology research includes elements of Autophagy and Transcription factor. His Ubiquitin study is related to the wider topic of Biochemistry.

His Proteasome research incorporates elements of Amino acid, Proteome, Moiety, Proteolysis and Intracellular. Aaron Ciechanover interconnects Cancer research, Gene knockdown, Downregulation and upregulation, NF-κB and DNA ligase in the investigation of issues within Ubiquitin ligase. The various areas that Aaron Ciechanover examines in his Protein degradation study include SUMO protein and Lysosome.

Between 2016 and 2021, his most popular works were:

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
  • The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy (248 citations)
  • The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy (248 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

Aaron Ciechanover mostly deals with Cell biology, Ubiquitin, Autophagy, Biochemistry and Protein degradation. His biological study spans a wide range of topics, including Biogenesis and Ubiquitin ligase. His work in Ubiquitin addresses issues such as Proteasome, which are connected to fields such as Proteolysis.

His studies in Autophagy integrate themes in fields like N-end rule, Binding site and Crosstalk. Aaron Ciechanover is interested in Programmed cell death, which is a field of Biochemistry. His Protein degradation research integrates issues from Lysosome, Deubiquitination, Moiety, Receptor and Globin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Ubiquitin System

Avram Hershko;Aaron Ciechanover.
Annual Review of Biochemistry (1998)

9789 Citations

The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction

Michael H. Glickman;Aaron Ciechanover.
Physiological Reviews (2002)

4727 Citations

The ubiquitin-proteasome proteolytic pathway

Aaron Ciechanover.
Cell (1994)

2225 Citations

The ubiquitin system for protein degradation

Avram Hershko;Aaron Ciechanover.
Annual Review of Biochemistry (1992)

1758 Citations

The ubiquitin–proteasome pathway: on protein death and cell life

Aaron Ciechanover.
The EMBO Journal (1998)

1712 Citations

pH and the recycling of transferrin during receptor-mediated endocytosis

Alice Dautry-Varsat;Aaron Ciechanover;Harvey F. Lodish.
Proceedings of the National Academy of Sciences of the United States of America (1983)

1519 Citations

Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.

A Hershko;H Heller;S Elias;A Ciechanover.
Journal of Biological Chemistry (1983)

1411 Citations

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1.

Gil Levkowitz;Hadassa Waterman;Seth A Ettenberg;Menachem Katz.
Molecular Cell (1999)

1215 Citations

Proteolysis: from the lysosome to ubiquitin and the proteasome.

Aaron Ciechanover.
Nature Reviews Molecular Cell Biology (2005)

1155 Citations

The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

Aaron Ciechanover;Patrik Brundin.
Neuron (2003)

1151 Citations

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