2023 - Research.com Biology and Biochemistry in Israel Leader Award
2022 - Research.com Biology and Biochemistry in Israel Leader Award
2016 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics
2013 - Fellow, National Academy of Inventors
2009 - Member of Academia Europaea
2009 - Centenary Prize, Royal Society of Chemistry (UK)
2008 - Fellow of the American Academy of Arts and Sciences
2008 - Member of the National Academy of Medicine (NAM)
2007 - Member of the National Academy of Sciences
2004 - Nobel Prize for the discovery of ubiquitin-mediated protein degradation
2004 - Member of the European Academy of Sciences
2000 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
Member of the European Academy of Sciences and Arts
Member of the Association of American Physicians
Foreign Member, Chinese Academy of Sciences
Member of the European Molecular Biology Organization (EMBO)
Aaron Ciechanover focuses on Ubiquitin, Biochemistry, Cell biology, Ubiquitin ligase and Proteasome. His research integrates issues of Lysosome, Protein degradation, Molecular biology, Affinity chromatography and Signal transduction in his study of Ubiquitin. His work in the fields of Proteolysis, Ubiquitins, Cell cycle and Ubiquitin-activating enzyme overlaps with other areas such as Covalent bond.
His Cell biology research integrates issues from Receptor, F-box protein, DNA repair and Monoubiquitination. His Ubiquitin ligase research is multidisciplinary, incorporating perspectives in Residue, Histone and DNA ligase. Protease is closely connected to Antigen processing in his research, which is encompassed under the umbrella topic of Proteasome.
Aaron Ciechanover mainly focuses on Ubiquitin, Cell biology, Biochemistry, Proteasome and Ubiquitin ligase. His research in Ubiquitin intersects with topics in Cell cycle, DNA ligase, Protein degradation and Proteolysis. His Cell biology research is multidisciplinary, relying on both Autophagy, Molecular biology, Transcription factor and Lysosome.
His studies in Ubiquitins, Enzyme, Ubiquitin-activating enzyme, Protease and Peptide sequence are all subfields of Biochemistry research. Aaron Ciechanover works mostly in the field of Proteasome, limiting it down to concerns involving Intracellular and, occasionally, RNA. Aaron Ciechanover has included themes like Deubiquitinating enzyme, Lysine, NF-κB, Phosphorylation and Protein structure in his Ubiquitin ligase study.
Aaron Ciechanover spends much of his time researching Cell biology, Ubiquitin, Proteasome, Ubiquitin ligase and Protein degradation. His Cell biology research includes elements of Autophagy and Transcription factor. His Ubiquitin study is related to the wider topic of Biochemistry.
His Proteasome research incorporates elements of Amino acid, Proteome, Moiety, Proteolysis and Intracellular. Aaron Ciechanover interconnects Cancer research, Gene knockdown, Downregulation and upregulation, NF-κB and DNA ligase in the investigation of issues within Ubiquitin ligase. The various areas that Aaron Ciechanover examines in his Protein degradation study include SUMO protein and Lysosome.
Aaron Ciechanover mostly deals with Cell biology, Ubiquitin, Autophagy, Biochemistry and Protein degradation. His biological study spans a wide range of topics, including Biogenesis and Ubiquitin ligase. His work in Ubiquitin addresses issues such as Proteasome, which are connected to fields such as Proteolysis.
His studies in Autophagy integrate themes in fields like N-end rule, Binding site and Crosstalk. Aaron Ciechanover is interested in Programmed cell death, which is a field of Biochemistry. His Protein degradation research integrates issues from Lysosome, Deubiquitination, Moiety, Receptor and Globin.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The Ubiquitin System
Avram Hershko;Aaron Ciechanover.
Annual Review of Biochemistry (1998)
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
Michael H. Glickman;Aaron Ciechanover.
Physiological Reviews (2002)
The ubiquitin-proteasome proteolytic pathway
The ubiquitin system for protein degradation
Avram Hershko;Aaron Ciechanover.
Annual Review of Biochemistry (1992)
The ubiquitin–proteasome pathway: on protein death and cell life
The EMBO Journal (1998)
pH and the recycling of transferrin during receptor-mediated endocytosis
Alice Dautry-Varsat;Aaron Ciechanover;Harvey F. Lodish.
Proceedings of the National Academy of Sciences of the United States of America (1983)
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.
A Hershko;H Heller;S Elias;A Ciechanover.
Journal of Biological Chemistry (1983)
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1.
Gil Levkowitz;Hadassa Waterman;Seth A Ettenberg;Menachem Katz.
Molecular Cell (1999)
Proteolysis: from the lysosome to ubiquitin and the proteasome.
Nature Reviews Molecular Cell Biology (2005)
The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.
Aaron Ciechanover;Patrik Brundin.
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