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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
12676
World Ranking
14324
National Ranking
1015

Overview

Wolfgang Wiechert is affiliated with Forschungszentrum Jülich in Germany and has contributed extensively to the domain of Biochemistry, Genetics, and Molecular Biology with a focus on Molecular Biology as a core subfield. Their research work spans a broad range of topics centered on microbial metabolic processes and biotechnology.

The scientist's main topics of work include:

  • Microbial Metabolic Engineering and Bioproduction
  • Viral Infectious Diseases and Gene Expression in Insects
  • Biofuel production and bioconversion
  • Gene Regulatory Network Analysis
  • Metabolomics and Mass Spectrometry Studies
  • Enzyme Catalysis and Immobilization
  • Innovative Microfluidic and Catalytic Techniques Innovation

Wolfgang Wiechert has published notably in several venues where they have multiple contributions. Frequent publication venues are:

  • Microbial Cell Factories
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Chemie Ingenieur Technik
  • Engineering in Life Sciences
  • Metabolic Engineering

Among recent published papers, key works include:

  • "Machine learning in bioprocess development: from promise to practice" (2022), published in Trends in Biotechnology
  • "bletl - A Python package for integrating BioLector microcultivation devices in the Design-Build-Test-Learn cycle" (2022), published in Engineering in Life Sciences
  • "High-Quality Genome-Scale Reconstruction of Corynebacterium glutamicum ATCC 13032" (2021), published in Frontiers in Microbiology
  • "Screening of a genome-reduced Corynebacterium glutamicum strain library for improved heterologous cutinase secretion" (2020), published in Microbial Biotechnology
  • "pyFOOMB: Python framework for object oriented modeling of bioprocesses" (2021), published in Engineering in Life Sciences

Their collaboration network includes multiple frequent co-authors, such as:

  • Marco Oldiges
  • Stephan Noack
  • Katharina Nöh
  • Laura M. Helleckes
  • Johannes Hemmerich

Best Publications

  • 13C metabolic flux analysis.

    Wolfgang Wiechert

  • Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing.

    Achim Marx;Albert A. de Graaf;Wolfgang Wiechert;Lothar Eggeling

  • A Universal Framework for 13C Metabolic Flux Analysis

    Wolfgang Wiechert;Michael Möllney;Sören Petersen;Albert A. de Graaf

  • Bidirectional reaction steps in metabolic networks: III. Explicit solution and analysis of isotopomer labeling systems.

    Wolfgang Wiechert;Michael Möllney;Nichole Isermann;Michael Wurzel

  • Bidirectional reaction steps in metabolic networks: I. Modeling and simulation of carbon isotope labeling experiments.

    Wolfgang Wiechert;Albert A. de Graaf

  • Bidirectional reaction steps in metabolic networks: II. Flux estimation and statistical analysis.

    Wolfgang Wiechert;Claudia Siefke;Albert A. de Graaf;Achim Marx

  • Modeling and simulation: tools for metabolic engineering.

    Wolfgang Wiechert

  • Extensive exometabolome analysis reveals extended overflow metabolism in various microorganisms

    Nicole Paczia;Anke Nilgen;Tobias Lehmann;Jochem Gätgens

  • Metabolic flux analysis at ultra short time scale: isotopically non-stationary 13C labeling experiments.

    Katharina Nöh;Karsten Grönke;Bing Luo;Ralf Takors

  • Bidirectional reaction steps in metabolic networks: IV. Optimal design of isotopomer labeling experiments.

    M Möllney;W Wiechert;D Kownatzki;A A de Graaf

  • In vivo quantification of parallel and bidirectional fluxes in the anaplerosis of Corynebacterium glutamicum.

    Sören Petersen;Albert A. de Graaf;Lothar Eggeling;Michael Möllney

  • 13CFLUX2 – High-Performance Software Suite for 13C-Metabolic Flux Analysis

    Michael Weitzel;Katharina Nöh;Tolga Dalman;Sebastian Niedenführ

  • New tools for mass isotopomer data evaluation in (13)C flux analysis: mass isotope correction, data consistency checking, and precursor relationships.

    S.Aljoscha Wahl;Michael Dauner;Wolfgang Wiechert

  • Single-cell microfluidics: opportunity for bioprocess development

    Alexander Grünberger;Wolfgang Wiechert;Dietrich Kohlheyer

  • 13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis

    Dany J.V. Beste;Katharina Nöh;Sebastian Niedenführ;Tom A. Mendum

  • Microbioreactor Systems for Accelerated Bioprocess Development

    Johannes Hemmerich;Stephan Noack;Wolfgang Wiechert;Marco Oldiges;Marco Oldiges

  • From stationary to instationary metabolic flux analysis.

    Wolfgang Wiechert;Katharina Nöh

  • Emerging Corynebacterium glutamicum systems biology.

    Volker F. Wendisch;Michael Bott;Jörn Kalinowski;Marco Oldiges

  • Optical sensors for monitoring dynamic changes of intracellular metabolite levels in mammalian cells

    Bi Huei Hou;Hitomi Takanaga;Guido Grossmann;Li Qing Chen

  • Collisional fragmentation of central carbon metabolites in LC‐MS/MS increases precision of 13C metabolic flux analysis

    Martin Rühl;Beat Rupp;Katharina Nöh;Wolfgang Wiechert

Frequent Co-Authors

Martina Pohl
Martina Pohl Forschungszentrum Jülich
Karl-Erich Jaeger
Karl-Erich Jaeger Heinrich Heine University Düsseldorf
Michael Bott
Michael Bott Forschungszentrum Jülich
Bernd Freisleben
Bernd Freisleben Philipp University of Marburg
Lars M. Blank
Lars M. Blank RWTH Aachen University
Jörn Kalinowski
Jörn Kalinowski Bielefeld University
Lothar Eggeling
Lothar Eggeling Forschungszentrum Jülich
Volker F. Wendisch
Volker F. Wendisch Bielefeld University
Hermann Sahm
Hermann Sahm Forschungszentrum Jülich
Alexander Mitsos
Alexander Mitsos RWTH Aachen University

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