World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
19881
World Ranking
9012
National Ranking
4004

Overview

Toshinori Hoshi is affiliated with the University of Pennsylvania in the United States and has contributed extensively to research in the fields of medicine and biochemistry, genetics, and molecular biology. Their work spans several subfields, including molecular biology, surgery, cardiology and cardiovascular medicine, cellular and molecular neuroscience, and endocrinology, diabetes and metabolism.

Their primary research interests cover a range of topics such as ion channel regulation and function, pancreatic function and diabetes, cardiac electrophysiology and arrhythmias, cardiac ischemia and reperfusion, heme oxygenase-1 and carbon monoxide, hyperglycemia and glycemic control in critically ill and hospitalized patients, and diabetes and associated disorders.

Recent papers authored or co-authored by Toshinori Hoshi include the following publications:

  • Decreased KATP Channel Activity Contributes to the Low Glucose Threshold for Insulin Secretion of Rat Neonatal Islets, 2021, Endocrinology
  • Monitoring of compound resting membrane potentials of cell cultures with ratiometric genetically encoded voltage indicators, 2021, Communications Biology
  • Bilirubin Oxidation End Products (BOXes) Induce Neuronal Oxidative Stress Involving the Nrf2 Pathway, 2021, Oxidative Medicine and Cellular Longevity
  • A GFP-based ratiometric sensor for cellular methionine oxidation, 2022, Talanta
  • Impact of intracellular hemin on N-type inactivation of voltage-gated K+ channels, 2020, Pflügers Archiv - European Journal of Physiology

Toshinori Hoshi has collaborated frequently with several researchers including Stefan H. Heinemann, Roland Schönherr, Guido Geßner, Juxiang Yang, and Batoul Hammoud.

Their work has appeared predominantly in the publication venues including bioRxiv (Cold Spring Harbor Laboratory), Endocrinology, Communications Biology, Oxidative Medicine and Cellular Longevity, and Talanta.

Best Publications

  • Biophysical and molecular mechanisms of shaker potassium channel inactivation

    Toshinori Hoshi;William N. Zagotta;Richard W. Aldrich

  • Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB

    William N. Zagotta;Toshinori Hoshi;Richard W. Aldrich

  • Two types of inactivation in Shaker K+ channels: Effects of alterations in the carboxy-terminal region

    Toshinori Hoshi;William N. Zagotta;Richard W. Aldrich

  • The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory.

    John A. Wemmie;Jianguo Chen;Jianguo Chen;Candice C. Askwith;Candice C. Askwith;Alesia M. Hruska-Hageman;Alesia M. Hruska-Hageman

  • Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels.

    J. Lopezbarneo;T. Hoshi;S. H. Heinemann;R. W. Aldrich

  • Deletion of brain dystroglycan recapitulates aspects of congenital muscular dystrophy

    Steven A. Moore;Fumiaki Saito;Jianguo Chen;Daniel E. Michele

  • Shaker potassium channel gating. III: Evaluation of kinetic models for activation

    William N. Zagotta;Toshinori Hoshi;Toshinori Hoshi;Richard W Aldrich

  • High-quality life extension by the enzyme peptide methionine sulfoxide reductase

    Hongyu Ruan;Xiang Dong Tang;Mai-Lei Chen;Mei-Ling A. Joiner

  • The I-II Loop of the Ca2+ Channel α1 Subunit Contains an Endoplasmic Reticulum Retention Signal Antagonized by the β Subunit

    Delphine Bichet;Véronique Cornet;Sandrine Geib;Edmond Carlier

  • Regulation of cell function by methionine oxidation and reduction

    Toshinori Hoshi;Stefan H. Heinemann

  • Carbon monoxide – physiology, detection and controlled release

    Stefan H. Heinemann;Toshinori Hoshi;Matthias Westerhausen;Alexander Schiller

  • Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels

    Xiang Dong Tang;Rong Xu;Mark F. Reynolds;Maria L. Garcia

  • Oxygen sensing in the body.

    S. Lahiri;A. Roy;S.M. Baby;T. Hoshi

  • Shaker potassium channel gating. II: Transitions in the activation pathway.

    W N Zagotta;T Hoshi;J Dittman;R W Aldrich

  • Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function

    Herbert Weissbach;Frantzy Etienne;Toshinori Hoshi;Stefan H. Heinemann

  • Regulation of voltage dependence of the KAT1 channel by intracellular factors.

    Toshinori Hoshi

  • Modulation of potassium channel function by methionine oxidation and reduction.

    Matthew A. Ciorba;Stefan H. Heinemann;Herbert Weissbach;Nathan Brot

  • Effect of forskolin on voltage-gated K+ channels is independent of adenylate cyclase activation

    Toshinori Hoshi;Sarah S. Garber;Richard W. Aldrich

  • Shaker potassium channel gating. I: Transitions near the open state.

    Toshinori Hoshi;William N. Zagotta;William N. Zagotta;Richard W. Aldrich

  • Methionine sulfoxide reductase A protects neuronal cells against brief hypoxia/reoxygenation.

    Olena Yermolaieva;Rong Xu;Carrie Schinstock;Nathan Brot

Frequent Co-Authors

Stefan H. Heinemann
Stefan H. Heinemann Friedrich Schiller University Jena
Richard W. Aldrich
Richard W. Aldrich The University of Texas at Austin
Nathan Brot
Nathan Brot Cornell University
Clay M. Armstrong
Clay M. Armstrong University of Pennsylvania
Clay M. Armstrong
Clay M. Armstrong University of Pennsylvania
Irene Marten
Irene Marten University of Würzburg
Michael Bauer
Michael Bauer TU Dresden
Reynold A. Panettieri
Reynold A. Panettieri Rutgers, The State University of New Jersey
Michael J. Welsh
Michael J. Welsh University of Iowa
Chun-Fang Wu
Chun-Fang Wu University of Iowa

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Toshinori Hoshi

Trending Scientists

Recently Published Articles