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Bertrand Friguet

Bertrand Friguet

Sorbonne University
France

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
19327
World Ranking
5341
National Ranking
151

Bertrand Friguet publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Bertrand Friguet sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 208 publications — 53rd percentile

53% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Bertrand Friguet D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Bertrand Friguet sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 75 D-Index — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Bertrand Friguet is affiliated with Sorbonne University in France and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research primarily addresses molecular mechanisms underlying aging, cellular senescence, and redox biology. The scientist's work spans subfields including molecular biology, immunology, dermatology, biochemistry, and cancer research.

Friguet's main research topics encompass:

  • Redox biology and oxidative stress
  • Skin protection and aging
  • Mitochondrial function and pathology
  • Genetics, aging, and longevity in model organisms
  • Cancer, hypoxia, and metabolism
  • Telomeres, telomerase, and senescence
  • Neutrophil, myeloperoxidase, and oxidative mechanisms

The scientist's recent papers include:

  • Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework, 2020, published in Mechanisms of Ageing and Development
  • A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism, 2024, published in Nature Metabolism
  • Effects of cellular senescence on metabolic pathways in non-immune and immune cells, 2020, published in Mechanisms of Ageing and Development
  • Glyoxal Induces Senescence in Human Keratinocytes through Oxidative Stress and Activation of the Protein Kinase B/FOXO3a/p27KIP1 Pathway, 2021, published in Journal of Investigative Dermatology
  • Thioredoxin-1 and its mimetic peptide improve systolic cardiac function and remodeling after myocardial infarction, 2023, published in The FASEB Journal

Frequent publication venues where Friguet has contributed include:

  • Free Radical Biology and Medicine (9 publications)
  • Archives of Cardiovascular Diseases Supplements (4 publications)
  • Mechanisms of Ageing and Development (2 publications)
  • Journal of Investigative Dermatology (2 publications)
  • Nature Metabolism (1 publication)

Friguet collaborates regularly with several researchers, notably:

  • Dominique Couchie
  • Mustapha Rouis
  • Tania Medali
  • Aurore L'honoré
  • Nathalie Mougenot

The scientist's body of work reflects a multidisciplinary approach linking biochemical pathways and molecular mechanisms to physiological and pathological processes related to aging and cellular senescence. The integrated study of redox biology, lipid metabolism, and mitochondrial function is evident across the publications and coauthorship networks.

Best Publications

  • Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay.

    Bertrand Friguet;Alain F. Chaffotte;Lisa Djavadi-Ohaniance;Michel E. Goldberg

  • NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

    Amna Abderrazak;Tatiana Syrovets;Dominique Couchie;Khadija El Hadri

  • Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat

    Viviana I. Pérez;Rochelle Buffenstein;Venkata Masamsetti;Shanique Leonard

  • Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

    Niki Chondrogianni;Fiona L.L. Stratford;Ioannis P. Trougakos;Bertrand Friguet

  • Modification of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Formation of cross-linked protein that inhibits the multicatalytic protease.

    Bertrand Friguet;Earl R. Stadtman;Luke I. Szweda

  • Oxidative Modification and Inactivation of the Proteasome during Coronary Occlusion/Reperfusion

    Anne Laure Bulteau;Kathleen C. Lundberg;Kenneth M. Humphries;Hesham A. Sadek

  • Impairment of proteasome structure and function in aging

    Géraldine Carrard;Anne-Laure Bulteau;Isabelle Petropoulos;Bertrand Friguet

  • Autophagy Impairment in Muscle Induces Neuromuscular Junction Degeneration and Precocious Aging

    Silvia Carnio;Francesca LoVerso;Martin Andres Baraibar;Emanuela Longa

  • Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein

    Bertrand Friguet;Luke I Szweda

  • Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

    Günter U. Höglinger;Géraldine Carrard;Patrick P. Michel;Fadia Medja

  • A convenient enzyme-linked immunosorbent assay for testing whether monoclonal antibodies recognize the same antigenic site. Application to hybridomas specific for the beta 2-subunit of Escherichia coli tryptophan synthase.

    Bertrand Friguet;Lisa Djavadi-Ohaniance;Jacqueline Pages;Alain Bussard

  • Age-dependent declines in proteasome activity in the heart.

    Anne-Laure Bulteau;Luke I. Szweda;Bertrand Friguet

  • Some monoclonal antibodies raised with a native protein bind preferentially to the denatured antigen.

    Bertrand Friguet;Lisa Djavadi-Ohaniance;Michel E. Goldberg

  • Oxidized protein degradation and repair in ageing and oxidative stress.

    Bertrand Friguet

  • Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-β1 signaling pathway

    Florence Debacq-Chainiaux;Céline Borlon;Thierry Pascal;Véronique Royer

  • Age-related decline of rat liver multicatalytic proteinase activity and protection from oxidative inactivation by heat-shock protein 90.

    Mariangela Conconi;Luke I. Szweda;Rodney L. Levine;Earl R. Stadtman

  • Protein damage, repair and proteolysis.

    Niki Chondrogianni;Isabelle Petropoulos;Stefanie Grimm;Konstantina Georgila

  • MARK-AGE biomarkers of ageing

    Alexander Bürkle;María Moreno-Villanueva;Jürgen Bernhard;María Blasco

  • Fibroblast cultures from healthy centenarians have an active proteasome.

    N Chondrogianni;I Petropoulos;C Franceschi;B Friguet

  • Age-related alterations of proteasome structure and function in aging epidermis.

    A.-L Bulteau;I Petropoulos;B Friguet

Frequent Co-Authors

Michel E. Goldberg
Michel E. Goldberg Université Paris Cité
Efstathios S. Gonos
Efstathios S. Gonos National Hellenic Research Foundation
Zhenlin Li
Zhenlin Li Université Paris Cité
Claudio Franceschi
Claudio Franceschi University of Bologna
Luke I. Szweda
Luke I. Szweda The University of Texas Southwestern Medical Center
Earl R. Stadtman
Earl R. Stadtman National Institutes of Health
Tamas Fulop
Tamas Fulop Université de Sherbrooke
Etienne C. Hirsch
Etienne C. Hirsch Sorbonne University
Vadim N. Gladyshev
Vadim N. Gladyshev Brigham and Women's Hospital
Tilman Grune
Tilman Grune University of Potsdam

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Best Scientists Citing Bertrand Friguet

Tilman Grune

Tilman Grune

University of Potsdam

Publications: 141

Efstathios S. Gonos

Efstathios S. Gonos

National Hellenic Research Foundation

Publications: 55

Kelvin J.A. Davies

Kelvin J.A. Davies

University of Southern California

Publications: 49

Vadim N. Gladyshev

Vadim N. Gladyshev

Brigham and Women's Hospital

Publications: 48

Claudio Franceschi

Claudio Franceschi

University of Bologna

Publications: 43

Jeffrey N. Keller

Jeffrey N. Keller

Pennington Biomedical Research Center

Publications: 39

Olivier Toussaint

Olivier Toussaint

University of Namur

Publications: 37

Rochelle Buffenstein

Rochelle Buffenstein

The University of Texas Health Science Center at San Antonio

Publications: 33

D. Allan Butterfield

D. Allan Butterfield

University of Kentucky

Publications: 28

Earl R. Stadtman

Earl R. Stadtman

National Institutes of Health

Publications: 26

Arlan Richardson

Arlan Richardson

University of Oklahoma Health Sciences Center

Publications: 24

Suresh I. S. Rattan

Suresh I. S. Rattan

Aarhus University

Publications: 24

Heinz D. Osiewacz

Heinz D. Osiewacz

Goethe University Frankfurt

Publications: 24

Rodney L. Levine

Rodney L. Levine

National Institutes of Health

Publications: 23

Michel E. Goldberg

Michel E. Goldberg

Université Paris Cité

Publications: 19

Etienne C. Hirsch

Etienne C. Hirsch

Sorbonne University

Publications: 19

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