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Neuroscience

D-Index
77
Citations
18431
World Ranking
1860
National Ranking
891

Overview

H. Steve White is affiliated with the University of Washington in the United States. Their research primarily focuses on epilepsy, neuroscience, and pharmacology, with a significant contribution to understanding mechanisms of seizure activity and drug resistance.

The scientist has published extensively in the fields of medicine and neuroscience, with a total of 72 publications in medicine and 36 in neuroscience. Their research also spans important subfields including cellular and molecular neuroscience, psychiatry and mental health, pediatrics, perinatology, child health, molecular biology, and oncology.

Main topics covered in their work include epilepsy research and treatment, neuroscience and neuropharmacology research, pharmacological effects and toxicity studies, ion channel regulation and function, drug transport and resistance mechanisms, cholesterol and lipid metabolism, and pharmaceutical practices and patient outcomes.

Frequent publication venues for H. Steve White include:

  • Epilepsia
  • Epilepsy & Behavior
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Epilepsia Open
  • CNS Drugs

Co-authors who have regularly collaborated with White include:

  • Melissa Barker-Haliski
  • Dannielle Zierath
  • Emilio Perucca
  • Kevin M. Knox
  • Meir Bialer

Recent papers published by H. Steve White reflect a focus on new therapies and drug resistance in epilepsy:

  • "Drug resistance in epilepsy", 2023, The Lancet Neurology
  • "Progress report on new antiepileptic drugs: A summary of the Fifteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XV). I. Drugs in preclinical and early clinical development", 2020, Epilepsia
  • "New GABA-Targeting Therapies for the Treatment of Seizures and Epilepsy: I. Role of GABA as a Modulator of Seizure Activity and Recently Approved Medications Acting on the GABA System", 2023, CNS Drugs
  • "Cenobamate (XCOPRI): Can preclinical and clinical evidence provide insight into its mechanism of action?", 2020, Epilepsia
  • "The ups and downs of alkyl-carbamates in epilepsy therapy: How does cenobamate differ?", 2021, Epilepsia

Best Publications

  • Key factors in the discovery and development of new antiepileptic drugs.

    Meir Bialer;H. Steve White

  • Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy

    Matthew E. Barton;Brian D. Klein;Harold H. Wolf;H. Steve White

  • Infections, inflammation and epilepsy

    Annamaria Vezzani;Robert S. Fujinami;H. Steve White;Pierre Marie Preux

  • Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold

    H.Steve White;S.Douglas Brown;Jose H Woodhead;Gwendolyn A Skeen

  • Glutamatergic Mechanisms Associated with Seizures and Epilepsy

    Melissa Barker-Haliski;H. Steve White

  • D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures

    Angelika Rostock;Christine Tober;Chris Rundfeldt;Reni Bartsch

  • Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor.

    Richard B. Carter;Paul L. Wood;Scott Wieland;Jon E. Hawkinson

  • Clinical Significance of Animal Seizure Models and Mechanism of Action Studies of Potential Antiepileptic Drugs

    H. Steve White

  • A Role of SCN9A in Human Epilepsies, As a Cause of Febrile Seizures and As a Potential Modifier of Dravet Syndrome

    Nanda A. Singh;Chris Pappas;E. Jill Dahle;Lieve R. F. Claes

  • Topiramate Modulates GABA‐Evoked Currents in Murine Cortical Neurons by a Nonbenzodiazepine Mechanism

    Unknown

  • Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX).

    Meir Bialer;Svein I. Johannessen;René H. Levy;Emilio Perucca

  • Preclinical development of antiepileptic drugs: past, present, and future directions.

    H. Steve White

  • Progress report on new antiepileptic drugs: A summary of the Eleventh Eilat Conference (EILAT XI)

    Meir Bialer;Svein I. Johannessen;René H. Levy;Emilio Perucca

  • Identification of new epilepsy treatments: Issues in preclinical methodology

    Aristea S. Galanopoulou;Paul S. Buckmaster;Kevin J. Staley;Solomon L. Moshé

  • A Novel Gene Causing a Mendelian Audiogenic Mouse Epilepsy

    Shana L. Skradski;Anna M. Clark;Hiamio Jiang;H. Steve White

  • Comparative Anticonvulsant and Mechanistic Profile of the Established and Newer Antiepileptic Drugs

    Unknown

  • Mechanisms of Action of Antiepileptic Drugs

    H. Steve White;Misty D. Smith;Karen S. Wilcox

  • Glutamate and GABA synthesis, release, transport and metabolism as targets for seizure control.

    Nicole M. Rowley;Karsten K. Madsen;Arne Schousboe;H. Steve White

  • Discovery of antiepileptic drugs.

    Misty Smith;Karen S. Wilcox;H. Steve White

  • Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs

    Karsten K. Madsen;H. Steve White;Arne Schousboe

  • Therapy discovery for pharmacoresistant epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop.

    James P. Stables;Ed Bertram;F. E. Dudek;Greg Holmes

  • Acetoacetate, acetone, and dibenzylamine (a contaminant in L-(+)-β-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo

    Jong M. Rho;Gail D. Anderson;Sean D. Donevan;H. Steve White

Frequent Co-Authors

Karen S. Wilcox
Karen S. Wilcox University of Utah
Svein I. Johannessen
Svein I. Johannessen Oslo University Hospital
Graeme J. Sills
Graeme J. Sills University of Glasgow
Scott W. Rogers
Scott W. Rogers University of Utah
Dixon M. Woodbury
Dixon M. Woodbury University of Utah
Louis J. Ptáček
Louis J. Ptáček University of California, San Francisco
Wayne N. Frankel
Wayne N. Frankel Columbia University
Ying-Hui Fu
Ying-Hui Fu University of California, San Francisco
Mark Leppert
Mark Leppert University of Utah
Jacqueline A. French
Jacqueline A. French New York University

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