World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
9578
World Ranking
14590
National Ranking
6114

Overview

Nina Isoherranen is a researcher affiliated with the University of Washington in the United States. Their work spans a multidisciplinary approach within medicine, particularly focusing on pharmacogenetics and drug metabolism as well as biochemical and molecular biology fields.

The main fields of study Nina Isoherranen contributes to include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader categories, their subfields of study encompass:

  • Molecular Biology
  • Pharmacology
  • Pediatrics, Perinatology and Child Health
  • Oncology
  • Biochemistry

The primary research topics encompass:

  • Pharmacogenetics and Drug Metabolism
  • Retinoids in leukemia and cellular processes
  • Drug Transport and Resistance Mechanisms
  • Antioxidant Activity and Oxidative Stress
  • Pharmacological Effects and Toxicity Studies
  • Metabolomics and Mass Spectrometry Studies
  • Peroxisome Proliferator-Activated Receptors

Nina Isoherranen has published extensively, with frequent venues including:

  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • The FASEB Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical and Translational Science

Recent papers authored or co-authored by Nina Isoherranen illustrate a focus on drug metabolism, clinical pharmacology, and molecular biology:

  • 3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration, 2021, Clinical and Translational Science
  • Gut commensals expand vitamin A metabolic capacity of the mammalian host, 2022, Cell Host & Microbe
  • Altered vitamin A metabolism in human liver slices corresponds to fibrogenesis, 2020, Clinical and Translational Science
  • In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19, 2021, Scientific Reports
  • Development of best practices in physiologically based pharmacokinetic modeling to support clinical pharmacology regulatory decision-making-A workshop summary, 2021, CPT Pharmacometrics & Systems Pharmacology

Collaboratively, Nina Isoherranen works closely with several frequent co-authors, highlighting a network of professional scientific relationships:

  • Lindsay C. Czuba
  • Guo Zhong
  • Sara Shum
  • Weize Huang
  • Aprajita S. Yadav

Best Publications

  • Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification

    Jennifer E Sager;Jinngjing Yu;Isabelle Ragueneau-Majlessi;Nina Isoherranen

  • EFFECT OF CYP3A5 POLYMORPHISM ON TACROLIMUS METABOLIC CLEARANCE IN VITRO

    Yang Dai;Mary F. Hebert;Nina Isoherranen;Connie L. Davis

  • ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION

    Nina Isoherranen;Kent L. Kunze;Kyle E. Allen;Wendel L. Nelson

  • Cannabis use during pregnancy: Pharmacokinetics and effects on child development.

    Kimberly S. Grant;Rebekah Petroff;Nina Isoherranen;Nephi Stella

  • EVIDENCE OF SIGNIFICANT CONTRIBUTION FROM CYP3A5 TO HEPATIC DRUG METABOLISM

    Weili Huang;Yvonne S. Lin;Donavon J. McConn;Justina C. Calamia

  • Drug metabolism and transport during pregnancy: how does drug disposition change during pregnancy and what are the mechanisms that cause such changes?

    Nina Isoherranen;Kenneth E. Thummel

  • The role of CYP26 enzymes in retinoic acid clearance.

    Jayne E Thatcher;Nina Isoherranen

  • Commensals Suppress Intestinal Epithelial Cell Retinoic Acid Synthesis to Regulate Interleukin-22 Activity and Prevent Microbial Dysbiosis.

    Mayara Grizotte-Lake;Guo Zhong;Kellyanne Duncan;Jay Kirkwood

  • Contribution of Itraconazole Metabolites to Inhibition of CYP3A4 In Vivo

    Ian Templeton;Kenneth E Thummel;Evan D Kharasch;Kent L Kunze

  • Suppression of Spermatogenesis by Bisdichloroacetyldiamines Is Mediated by Inhibition of Testicular Retinoic Acid Biosynthesis

    John K. Amory;Charles H. Muller;Jakob A. Shimshoni;Nina Isoherranen

  • 3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration.

    Hongbing Wang;Paul C. Brown;Edwin C.Y. Chow;Lorna Ewart

  • Chromatographic methods for analysis of aminoglycoside antibiotics.

    Nina Isoherranen;Stefan Soback

  • Processive Pulses of Retinoic Acid Propel Asynchronous and Continuous Murine Sperm Production

    Cathryn A. Hogarth;Samuel Arnold;Travis Kent;Debra Mitchell

  • A sensitive and specific method for measurement of multiple retinoids in human serum with UHPLC-MS/MS

    Samuel L.M. Arnold;John K. Amory;Thomas J. Walsh;Nina Isoherranen

  • Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.

    Rama Subba Rao Vidadala;Kasey L. Rivas;Kayode K. Ojo;Matthew A. Hulverson

  • Comparison of the Function and Expression of CYP26A1 and CYP26B1, the two Retinoic Acid Hydroxylases

    Ariel R. Topletz;Jayne E. Thatcher;Alex Zelter;Justin D. Lutz

  • Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam.

    E D Kharasch;A Walker;N Isoherranen;C Hoffer

  • New CNS-active drugs which are second-generation valproic acid: can they lead to the development of a magic bullet?

    Nina Isoherranen;Boris Yagen;Meir Bialer

  • Inhibition of CYP2C19 and CYP3A4 by Omeprazole Metabolites and Their Contribution to Drug-Drug Interactions

    Yoshiyuki Shirasaka;Jennifer E. Sager;Justin D. Lutz;Connie Davis

  • Special Section on Pregnancy—Commentary Drug Metabolism and Transport During Pregnancy: How Does Drug Disposition Change during Pregnancy and What Are the Mechanisms that Cause Such Changes?

    Nina Isoherranen;Kenneth E. Thummel

Frequent Co-Authors

Kenneth E. Thummel
Kenneth E. Thummel University of Washington
Kent L. Kunze
Kent L. Kunze University of Washington
Michael D. Griswold
Michael D. Griswold Washington State University
Richard H. Finnell
Richard H. Finnell Baylor College of Medicine
Thomas J. Walsh
Thomas J. Walsh Weill Cornell Medicine
H. Steve White
H. Steve White University of Washington
Wesley C. Van Voorhis
Wesley C. Van Voorhis University of Washington
Jashvant D. Unadkat
Jashvant D. Unadkat University of Washington
Volker Schurig
Volker Schurig University of Tübingen
David R. Goodlett
David R. Goodlett University of Victoria

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology and Biochemistry opens doors to a variety of online degrees and careers in the health sciences. Many students choose flexible programs that offer pathways into in-demand roles, from nursing to healthcare management.

For those with a nursing background, an easiest rn to bsn program can be an ideal choice. These programs are designed to help registered nurses quickly advance to a Bachelor of Science in Nursing, often fully online.

If you are more interested in leadership, consider an accelerated healthcare management degree online. These degrees can fast-track your entry into high-level administrative positions in hospitals and clinics.

Mental health is another fast-growing sector. A fast track mental health nursing program empowers nurses to specialize in psychiatric care through online study, meeting a critical need in healthcare.

Finally, a fast track nutrition degree online can prepare students for careers in dietetics, wellness coaching, or public health. These degrees combine science knowledge with practical skills for the health industry.

Best Scientists Citing Nina Isoherranen

Trending Scientists

Recently Published Articles