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Koji Yamanaka

Koji Yamanaka

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
28270
World Ranking
15881
National Ranking
1134

Overview

Koji Yamanaka is affiliated with Nagoya University in Japan. Their research predominantly spans the fields of Medicine and Neuroscience, with particular focus areas in Neurology, Molecular Biology, Genetics, Physiology, and Cellular and Molecular Neuroscience.

The main topics covered in Yamanaka's research include Amyotrophic Lateral Sclerosis Research, Neuroinflammation and Neurodegeneration Mechanisms, Neurogenetic and Muscular Disorders Research, Alzheimer's Disease Research and Treatments, Tryptophan and Brain Disorders, Cholinesterase and Neurodegenerative Diseases, and Immune Cells in Cancer.

Yamanaka has published extensively in several scientific venues. These include:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Communications Biology
  • Molecular Brain
  • Scientific Reports
  • Frontiers in Cellular Neuroscience

Recent papers authored or co-authored by Yamanaka highlight key contributions to neurodegenerative disease and cellular mechanisms, such as:

  • Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease, 2021, Acta Neuropathologica Communications
  • Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair, 2020, Cell
  • Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction, 2020, The EMBO Journal
  • Neuroinflammation in Alzheimer's disease: microglial signature and their relevance to disease, 2023, Inflammation and Regeneration
  • Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype, 2023, Communications Biology

Frequent collaborators in their research include:

  • Okiru Komine
  • Akira Sobue
  • Seiji Watanabe
  • Tomoo Ogi
  • Hiroyuki Mizoguchi

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Neuroinflammation in Alzheimer's disease

    Michael T Heneka;Monica J Carson;Joseph El Khoury;Gary E Landreth

  • Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia

    Séverine Boillée;Koji Yamanaka;Christian S. Lobsiger;Neal G. Copeland

  • Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.

    Koji Yamanaka;Seung Joo Chun;Severine Boillee;Noriko Fujimori-Tonou

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

    Kazuhiro Iwai;Koji Yamanaka;Takumi Kamura;Nagahiro Minato

  • Antisense oligonucleotide therapy for neurodegenerative disease

    Richard A. Smith;Timothy M. Miller;Koji Yamanaka;Brett P. Monia

  • NEDD8 recruits E2-ubiquitin to SCF E3 ligase

    Takayuki Kawakami;Tomoki Chiba;Toshiaki Suzuki;Kazuhiro Iwai

  • Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice

    Koji Yamanaka;Severine Boillee;Elizabeth A. Roberts;Michael L. Garcia;Michael L. Garcia

  • Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS

    Adrian Israelson;Nir Arbel;Sandrine Da Cruz;Hristelina Ilieva

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • A Seeding Reaction Recapitulates Intracellular Formation of Sarkosyl-insoluble Transactivation Response Element (TAR) DNA-binding Protein-43 Inclusions

    Yoshiaki Furukawa;Kumi Kaneko;Shoji Watanabe;Koji Yamanaka

  • Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis.

    Yoshiaki Furukawa;Kumi Kaneko;Koji Yamanaka;Thomas V. O'Halloran

  • Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2.

    Koji Yamanaka;Haruto Ishikawa;Haruto Ishikawa;Yuzuru Megumi;Fuminori Tokunaga

  • Loss of TDP-43 causes age-dependent progressive motor neuron degeneration.

    Yohei Iguchi;Masahisa Katsuno;Jun Ichi Niwa;Shinnosuke Takagi

  • Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

    Hitomi Tsuiji;Yohei Iguchi;Asako Furuya;Ayane Kataoka

  • Mitochondria‐associated membrane collapse is a common pathomechanism in SIGMAR1‐ and SOD1‐linked ALS

    Seiji Watanabe;Hristelina Ilieva;Hristelina Ilieva;Hiromi Tamada;Hanae Nomura

  • Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis.

    Timothy M. Miller;Soo H. Kim;Koji Yamanaka;Mark Hester

  • Glial cells in amyotrophic lateral sclerosis.

    Jurate Lasiene;Koji Yamanaka;Koji Yamanaka

  • Neuroinfl ammation in Alzheimer's disease

    Michael T Heneka;Monica J Carson;Joseph El Khoury;Gary E Landreth

Frequent Co-Authors

Don W. Cleveland
Don W. Cleveland University of California, San Diego
Hidemi Misawa
Hidemi Misawa Keio University
Nobuyuki Nukina
Nobuyuki Nukina Doshisha University
Ryosuke Takahashi
Ryosuke Takahashi Kyoto University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Gen Sobue
Gen Sobue Aichi Medical University
Shinji Ohara
Shinji Ohara Johns Hopkins University
Kazuhiro Iwai
Kazuhiro Iwai Kyoto University
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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