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Best Scientists
2025
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Biology and Biochemistry
USA
2026

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Best Scientists

D-Index
168
Citations
109320
World Ranking
946
National Ranking
561

Biology and Biochemistry

D-Index
162
Citations
101535
World Ranking
113
National Ranking
86

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award

Overview

Robert H. Brown is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research output covers a broad area within medicine, particularly focused on neurological and genetic disorders.

The main fields of study for Robert H. Brown are Medicine and Biochemistry, Genetics and Molecular Biology. Within these domains, their subfields of study include Neurology, Genetics, Molecular Biology, Physiology, and Cellular and Molecular Neuroscience.

The main topics addressed in their work are:

  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Parkinson's Disease Mechanisms and Treatments
  • Biodegradable Polymer Synthesis and Properties
  • Prion Diseases and Protein Misfolding
  • Neurological Diseases and Metabolism
  • RNA Interference and Gene Delivery

Frequent coauthors collaborating with Robert H. Brown include:

  • Alexandra Weiss (12 joint publications)
  • Catherine Douthwright (10 joint publications)
  • James D. Berry (9 joint publications)
  • Diane McKenna-Yasek (9 joint publications)
  • Robert Bowser (9 joint publications)

Key publication venues for their work are:

  • bioRxiv (Cold Spring Harbor Laboratory) with 9 publications
  • Nature Communications with 5 publications
  • Nature Medicine with 3 publications
  • Annals of Neurology with 3 publications
  • Muscle & Nerve with 2 publications

Some notable recent papers authored or coauthored by Robert H. Brown include:

  • Immediate and long-term consequences of COVID-19 infections for the development of neurological disease, 2020, Alzheimer s Research & Therapy
  • SOD1 Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS, 2020, New England Journal of Medicine
  • Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide, 2021, Nature Medicine
  • Childhood amyotrophic lateral sclerosis caused by excess sphingolipid synthesis, 2021, Nature Medicine
  • Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides, 2020, Proceedings of the National Academy of Sciences

Best Publications

  • Dystrophin: The protein product of the duchenne muscular dystrophy locus

    Eric P. Hoffman;Robert H. Brown;Louis M. Kunkel;Louis M. Kunkel

  • Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.

    T. J. Kwiatkowski;D. A. Bosco;D. A. Bosco;A. L. LeClerc;A. L. LeClerc;E. Tamrazian

  • Decoding ALS: from genes to mechanism

    J. Paul Taylor;Robert H. Brown;Don W. Cleveland;Don W. Cleveland

  • Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury.

    Andrew. G. Reaume;Jeffrey L. Elliott;Eric K. Hoffman;Neil W. Kowall;Neil W. Kowall

  • Molecular biology of amyotrophic lateral sclerosis: insights from genetics.

    Piera Pasinelli;Robert H. Brown

  • Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.

    A. M. Clement;M. D. Nguyen;E. A. Roberts;E. A. Roberts;M. L. Garcia;M. L. Garcia

  • Mutant dynactin in motor neuron disease.

    Imke Puls;Catherine Jonnakuty;Bernadette H. LaMonte;Erika L.F. Holzbaur

  • Characterization of dystrophin in muscle-biopsy specimens from patients with Duchenne's or Becker's muscular dystrophy

    Hoffman Ep;Fischbeck Kh;Brown Rh;Johnson M

  • Dysferlin, a novel skeletal muscle gene, is mutated in Miyoshi myopathy and limb girdle muscular dystrophy

    Jing Liu;Masashi Aoki;Isabel Illa;Chenyan Wu

  • Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

    Elizabeth T. Cirulli;Brittany N Lasseigne;Slave Petrovski;Peter C Sapp

  • Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis.

    Ferrante Rj;Browne Se;Shinobu La;Bowling Ac

  • Superoxide Dismutase Activity, Oxidative Damage, and Mitochondrial Energy Metabolism in Familial and Sporadic Amyotrophic Lateral Sclerosis

    Bowling Ac;Schulz Jb;Brown Rh;Beal Mf

  • A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.

    Shinji Hadano;Collette K. Hand;Hitoshi Osuga;Yoshiko Yanagisawa

  • Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein.

    David E. James;Robert Brown;Javier Navarro;Paul F. Pilch

  • ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis

    Matthew J Greenway;Peter M Andersen;Carsten Russ;Sean Ennis

  • Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

    David R. Borchelt;Michael K. Lee;Hilda S. Slunt;Michael Guarnieri

  • Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

    Daryl A. Bosco;Gerardo A. Morfini;Gerardo A. Morfini;N. Murat Karabacak;Yuyu Song;Yuyu Song

  • Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules.

    Daryl Bosco;Nathan Lemay;Hae Kyung Ko;Hongru Zhou

  • Mutations in the Profilin 1 Gene Cause Familial Amyotrophic Lateral Sclerosis

    Chi Hong Wu;Claudia Fallini;Nicola Ticozzi;Pamela J. Keagle

  • Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis.

    M. E. Cudkowicz;D. McKenna-Yasek;P. E. Sapp;P. E. Sapp;W. Chin;W. Chin

Frequent Co-Authors

Roger N. Clark
Roger N. Clark Planetary Science Institute
Ralf Jaumann
Ralf Jaumann Freie Universität Berlin
Jason W. Barnes
Jason W. Barnes University of Idaho
Dale P. Cruikshank
Dale P. Cruikshank University of Central Florida
Christophe Sotin
Christophe Sotin Jet Propulsion Lab
S. Le Mouélic
S. Le Mouélic University of Nantes
Katrin Stephan
Katrin Stephan German Aerospace Center
P. Drossart
P. Drossart Université Paris Cité
Sebastien Rodriguez
Sebastien Rodriguez Institut de Physique du Globe de Paris

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