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Ryosuke Takahashi

Ryosuke Takahashi

D-Index & Metrics

Medicine

D-Index
92
Citations
38517
World Ranking
11148
National Ranking
320

Overview

Ryosuke Takahashi is affiliated with Kyoto University in Japan and has contributed extensively to the fields of medicine and neuroscience, especially within neurology and cognitive neuroscience. Their research spans diverse topics related to neurological disorders and treatments, with a primary focus on Parkinson's disease mechanisms and treatments. Other important research areas include EEG and brain-computer interfaces, epilepsy research and treatment, neuroinflammation and neurodegeneration mechanisms, functional brain connectivity studies, and amyotrophic lateral sclerosis research.

The scientist has published numerous papers across several notable venues. Frequent publication outlets include Clinical Neurophysiology, Movement Disorders, Rinsho Shinkeigaku, bioRxiv (Cold Spring Harbor Laboratory), and Neurology. These platforms reflect the breadth of Takahashi's research interests and their engagement with prominent journals in neurology and related fields.

Selected recent papers by Ryosuke Takahashi include:

  • The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC, 2020, Nature Cell Biology
  • Long-term Effect of Regular Physical Activity and Exercise Habits in Patients With Early Parkinson Disease, 2022, Kyoto University Research Information Repository (Kyoto University)
  • Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson's disease, 2025, Nature
  • Animal Model for Prodromal Parkinson's Disease, 2020, International Journal of Molecular Sciences
  • Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions, 2020, Translational Neurodegeneration

Takahashi frequently collaborates with several researchers, including Akio Ikeda, Riki Matsumoto, Akihiro Shimotake, Takayuki Kikuchi, and Hodaka Yamakado. These co-authors have worked with Takahashi on a significant number of publications, indicating established research partnerships.

The scientist's work also covers specialized subfields such as molecular biology, cellular and molecular neuroscience, and psychiatry and mental health. This interdisciplinary approach underscores Takahashi's involvement in bridging clinical applications with fundamental biological research.

Best Publications

  • X-linked IAP is a direct inhibitor of cell-death proteases

    Quinn L. Deveraux;Ryosuke Takahashi;Guy S. Salvesen;John C. Reed

  • A Serine Protease, HtrA2, Is Released from the Mitochondria and Interacts with XIAP, Inducing Cell Death

    Yasuyuki Suzuki;Yuzuru Imai;Hiroshi Nakayama;Kazuko Takahashi

  • An Unfolded Putative Transmembrane Polypeptide, which Can Lead to Endoplasmic Reticulum Stress, Is a Substrate of Parkin

    Yuzuru Imai;Mariko Soda;Haruhisa Inoue;Nobutaka Hattori

  • Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.

    Koji Yamanaka;Seung Joo Chun;Severine Boillee;Noriko Fujimori-Tonou

  • Parkin Suppresses Unfolded Protein Stress-induced Cell Death through Its E3 Ubiquitin-protein Ligase Activity *

    Yuzuru Imai;Mariko Soda;Ryosuke Takahashi

  • Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death.

    Yasuyuki Suzuki;Yui Nakabayashi;Ryosuke Takahashi

  • Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

    Takayuki Kondo;Masashi Asai;Masashi Asai;Kayoko Tsukita;Yumiko Kutoku

  • Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model

    Tetsuhiro Kikuchi;Asuka Morizane;Daisuke Doi;Hiroaki Magotani

  • A rotarod test for evaluation of motor skill learning.

    Hiromi Shiotsuki;Kenji Yoshimi;Yasushi Shimo;Manabu Funayama

  • Drug screening for ALS using patient-specific induced pluripotent stem cells.

    Naohiro Egawa;Shiho Kitaoka;Kayoko Tsukita;Motoko Naitoh

  • CHIP Is Associated with Parkin, a Gene Responsible for Familial Parkinson's Disease, and Enhances Its Ubiquitin Ligase Activity

    Yuzuru Imai;Mariko Soda;Shigetsugu Hatakeyama;Takumi Akagi

  • Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis.

    Makoto Urushitani;Attila Sik;Takashi Sakurai;Nobuyuki Nukina

  • Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

    Takanori Yokota;Kanako Sugawara;Kaoru Ito;Ryosuke Takahashi

  • Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila.

    Yuzuru Imai;Stephan Gehrke;Hua Qin Wang;Ryosuke Takahashi

  • Parkin Suppresses Dopaminergic Neuron-Selective Neurotoxicity Induced by Pael-R in Drosophila

    Yufeng Yang;Isao Nishimura;Yuzuru Imai;Ryosuke Takahashi

  • Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria

    Song Liu;Tomoyo Sawada;Seongsoo Lee;Wendou Yu

  • Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis.

    Makoto Urushitani;Junko Kurisu;Kayoko Tsukita;Ryosuke Takahashi

  • Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells

    Masatoshi Kajiwara;Takashi Aoi;Keisuke Okita;Ryosuke Takahashi

  • Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts

    Yoko Okamoto;Toru Yamamoto;Raj N. Kalaria;Hideto Senzaki

  • Selective Impairment of Working Memory in a Mouse Model of Chronic Cerebral Hypoperfusion

    Masunari Shibata;Nobuyuki Yamasaki;Tsuyoshi Miyakawa;Rajesh N. Kalaria

Frequent Co-Authors

Akio Ikeda
Akio Ikeda Kyoto University
Riki Matsumoto
Riki Matsumoto Kobe University
Masafumi Ihara
Masafumi Ihara Kyoto University
Takeharu Kunieda
Takeharu Kunieda Ehime University
Hidenao Fukuyama
Hidenao Fukuyama Kyoto University
Susumu Miyamoto
Susumu Miyamoto Kyoto University
Nobuhiro Mikuni
Nobuhiro Mikuni Sapporo Medical University
Shun Shimohama
Shun Shimohama Sapporo Medical University
Nobukatsu Sawamoto
Nobukatsu Sawamoto Kyoto University
Hidemi Misawa
Hidemi Misawa Keio University

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