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Brian K. Kaspar

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
23541
World Ranking
8966
National Ranking
3983

Brian K. Kaspar publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Brian K. Kaspar sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 178 publications — 40th percentile

40% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Brian K. Kaspar D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Brian K. Kaspar sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 65 D-Index — 55th percentile

55% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Brian K. Kaspar is affiliated with Insmed Incorporated in the United States, specializing in research spanning biochemistry, genetics, molecular biology, and medicine. Their work includes a focus on molecular biology and genetics within subfields such as cell biology, surgery, and endocrinology, diabetes, and metabolism.

The primary research topics Brian K. Kaspar has contributed to include:

  • Neurogenetic and Muscular Disorders Research
  • RNA modifications and cancer
  • Genetics and Neurodevelopmental Disorders
  • Muscle Physiology and Disorders
  • Muscle metabolism and nutrition
  • Thyroid Disorders and Treatments
  • RNA regulation and disease

The scientist has published extensively in several venues, with frequent contributions in:

  • Neurobiology of Aging
  • Molecular Therapy - Methods & Clinical Development
  • Cells
  • Thyroid
  • Molecular Therapy

Notable recent publications include:

  • "Neurotoxic Astrocytes Directly Converted from Sporadic and Familial ALS Patient Fibroblasts Reveal Signature Diversities and miR-146a Theragnostic Potential in Specific Subtypes," 2022, Cells
  • "Follistatin-induced muscle hypertrophy in aged mice improves neuromuscular junction innervation and function," 2021, Neurobiology of Aging
  • "AAV9-MCT8 Delivery at Juvenile Stage Ameliorates Neurological and Behavioral Deficits in a Mouse Model of MCT8-Deficiency," 2022, Thyroid
  • "Novel MECP2 gene therapy is effective in a multicenter study using two mouse models of Rett syndrome and is safe in non-human primates," 2023, Molecular Therapy
  • "Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease," 2023, Frontiers in Genetics

Their research collaborations feature frequent co-authors such as:

  • Kathrin Meyer
  • Shibi Likhite
  • Arthur H.M. Burghes
  • Chitra C. Iyer
  • Clive N. Svendsen

Brian K. Kaspar was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 2013, recognizing contributions to scientific research.

Best Publications

  • Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

    Kevin D Foust;Emily Nurre;Emily Nurre;Chrystal L Montgomery;Anna Hernandez

  • Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

    Brian K. Kaspar;Jerònia Lladó;Nushin Sherkat;Jeffrey D. Rothstein

  • Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

    Karen Lai;Brian K. Kaspar;Fred H. Gage;David V. Schaffer

  • Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

    Amanda M Haidet-Phillips;Mark E Hester;Carlos J Miranda;Kathrin Meyer

  • Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

    Kevin D Foust;Xueyong Wang;Vicki L McGovern;Lyndsey Braun

  • Cell culture. Progenitor cells from human brain after death.

    Theo D. Palmer;Philip H. Schwartz;Philippe Taupin;Brian Kaspar

  • Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

    Narendra Maheshri;James T Koerber;Brian K Kaspar;David V Schaffer

  • IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes

    Jenny Hsieh;James B. Aimone;Brian K. Kaspar;Tomoko Kuwabara

  • Systemic Gene Delivery in Large Species for Targeting Spinal Cord, Brain, and Peripheral Tissues for Pediatric Disorders

    Adam K Bevan;Adam K Bevan;Sandra Duque;Kevin D Foust;Pablo R Morales

  • The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.

    Christopher P Webster;Emma F Smith;Claudia S Bauer;Annekathrin Moller

  • Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS.

    Kathrin Meyer;Laura Ferraiuolo;Carlos J. Miranda;Shibi Likhite;Shibi Likhite

  • Adeno-Associated Virus Serotype 9 Transduction in the Central Nervous System of Nonhuman Primates

    Lluis Samaranch;Ernesto A. Salegio;Waldy San Sebastian;Adrian P. Kells

  • Improving Single Injection CSF Delivery of AAV9-mediated Gene Therapy for SMA: A Dose–response Study in Mice and Nonhuman Primates

    Kathrin Meyer;Laura Ferraiuolo;Leah Schmelzer;Lyndsey Braun

  • Adeno-associated virus effectively mediates conditional gene modification in the brain

    Brian K. Kaspar;Bryce Vissel;Tasha Bengoechea;Steven Crone

  • A Phase 1/2a Follistatin Gene Therapy Trial for Becker Muscular Dystrophy

    Jerry R Mendell;Jerry R Mendell;Zarife Sahenk;Zarife Sahenk;Vinod Malik;Ana M Gomez

  • Systemic delivery of MeCP2 rescues behavioral and cellular deficits in female mouse models of Rett syndrome.

    Saurabh K. Garg;Daniel T. Lioy;Daniel T. Lioy;Hélène Cheval;James C. McGann;James C. McGann

  • Early heart failure in the SMNΔ7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery

    Adam K. Bevan;Kirk R. Hutchinson;Kirk R. Hutchinson;Kevin D. Foust;Lyndsey Braun

  • A Conditional Deletion of the NR1 Subunit of the NMDA Receptor in Adult Spinal Cord Dorsal Horn Reduces NMDA Currents and Injury-Induced Pain

    Samantha M. South;Tatsuro Kohno;Brian K. Kaspar;Deborah Hegarty

  • Therapeutic AAV9-mediated Suppression of Mutant SOD1 Slows Disease Progression and Extends Survival in Models of Inherited ALS

    Kevin D Foust;Desirée L Salazar;Desirée L Salazar;Desirée L Salazar;Shibi Likhite;Shibi Likhite;Laura Ferraiuolo

  • Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes.

    Mark E. Hester;Matthew J. Murtha;Sungwon Song;Meghan Rao

Frequent Co-Authors

Jerry R. Mendell
Jerry R. Mendell The Ohio State University
Arthur H.M. Burghes
Arthur H.M. Burghes The Ohio State University
Zarife Sahenk
Zarife Sahenk Nationwide Children's Hospital
John T. Kissel
John T. Kissel The Ohio State University
Don W. Cleveland
Don W. Cleveland University of California, San Diego
Thomas W. Prior
Thomas W. Prior The Ohio State University
Kevin M. Flanigan
Kevin M. Flanigan The Ohio State University
Richard S. Finkel
Richard S. Finkel St. Jude Children's Research Hospital
David V. Schaffer
David V. Schaffer University of California, Berkeley
Fred H. Gage
Fred H. Gage Salk Institute for Biological Studies

External Links

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Best Scientists Citing Brian K. Kaspar

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David V. Schaffer

University of California, Berkeley

Publications: 79

Jerry R. Mendell

Jerry R. Mendell

The Ohio State University

Publications: 63

Guangping Gao

Guangping Gao

University of Massachusetts Chan Medical School

Publications: 58

Mavis Agbandje-McKenna

Mavis Agbandje-McKenna

University of Florida

Publications: 46

Christian L. Lorson

Christian L. Lorson

University of Missouri

Publications: 43

James M. Wilson

James M. Wilson

University of Pennsylvania

Publications: 42

Francesco Muntoni

Francesco Muntoni

University College London

Publications: 41

Eugenio Mercuri

Eugenio Mercuri

Catholic University of the Sacred Heart

Publications: 40

Nicholas M. Boulis

Nicholas M. Boulis

Emory University

Publications: 40

Simon N. Waddington

Simon N. Waddington

University College London

Publications: 37

Luk H. Vandenberghe

Luk H. Vandenberghe

Massachusetts Eye and Ear Infirmary

Publications: 35

Stefania Corti

Stefania Corti

University of Milan

Publications: 35

Thomas H. Gillingwater

Thomas H. Gillingwater

University of Edinburgh

Publications: 33

Dongsheng Duan

Dongsheng Duan

University of Missouri

Publications: 30

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Federico Mingozzi

University of Pennsylvania

Publications: 30

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Pamela J. Shaw

University of Sheffield

Publications: 28

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