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Molecular Biology

D-Index
66
Citations
21957
World Ranking
1602
National Ranking
811

Overview

Thomas W. Prior is affiliated with The Ohio State University in the United States. Their research spans multiple areas primarily within medicine and biochemistry, genetics, and molecular biology.

The scientist has contributed to various fields of study, including:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Their work extends into several subfields such as:

  • Molecular Biology
  • Genetics
  • Hematology
  • Surgery
  • Public Health, Environmental and Occupational Health

Thomas W. Prior's research covers a range of topics including:

  • Neurogenetic and Muscular Disorders Research
  • Acute Myeloid Leukemia Research
  • RNA modifications and cancer
  • Prion Diseases and Protein Misfolding
  • Congenital Anomalies and Fetal Surgery
  • Acute Lymphoblastic Leukemia research
  • Histone Deacetylase Inhibitors Research

The scientist has published in several journals, with frequent appearances in these venues:

  • Leukemia
  • Birth Defects Research
  • UNC Libraries
  • The Application of Clinical Genetics
  • Journal of Neuromuscular Diseases

Selected recent papers include:

  • Spinal Muscular Atrophy: Mutations, Testing, and Clinical Relevance (2021), The Application of Clinical Genetics
  • Revised Recommendations for the Treatment of Infants Diagnosed with Spinal Muscular Atrophy Via Newborn Screening Who Have 4 Copies of SMN2 (2020), Journal of Neuromuscular Diseases
  • Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial (2021), Leukemia
  • Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results (2021), Leukemia
  • Prospective Statewide Study of Universal Screening for Hereditary Colorectal Cancer: The Ohio Colorectal Cancer Prevention Initiative (2021), JCO Precision Oncology

Thomas W. Prior collaborates frequently with a consistent group of co-authors, including:

  • Richard A. Larson
  • Christian Thiede
  • Konstanze Döhner
  • Joseph Brandwein
  • Frederick R. Appelbaum

Best Publications

  • Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy

    Jerry R. Mendell;Samiah Al-Zaidy;Richard Shell;W. Dave Arnold

  • Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).

    Heather Hampel;Wendy L. Frankel;Edward Martin;Mark Arnold

  • A Single Nucleotide Difference That Alters Splicing Patterns Distinguishes the SMA Gene SMN1 From the Copy Gene SMN2

    Umrao R. Monani;Christian L. Lorson;D. William Parsons;Thomas W. Prior

  • Feasibility of screening for Lynch syndrome among patients with colorectal cancer.

    Heather Hampel;Wendy L. Frankel;Edward Martin;Mark Arnold

  • The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn–/– mice and results in a mouse with spinal muscular atrophy

    Umrao R. Monani;Michael Sendtner;Daniel D. Coovert;D. William Parsons

  • The Survival Motor Neuron Protein in Spinal Muscular Atrophy

    Daniel D. Coovert;Thanh T. Le;Patricia E. McAndrew;John Strasswimmer

  • Myoblast Transfer in the Treatment of Duchenne's Muscular Dystrophy

    Jerry R. Mendell;John T. Kissel;Anthony A. Amato;Wendy King

  • Identification of Proximal Spinal Muscular Atrophy Carriers and Patients by Analysis of SMNT and SMNC Gene Copy Number

    P.E. McAndrew;D.W. Parsons;L.R. Simard;C. Rochette

  • Phase II Clinical Trial of Sorafenib in Metastatic Medullary Thyroid Cancer

    Elaine T. Lam;Matthew D. Ringel;Richard T. Kloos;Thomas W. Prior

  • Molecular analysis of spinal muscular atrophy and modification of the phenotype by SMN2.

    Matthew D Mailman;John W Heinz;Audrey C Papp;Pamela J Snyder

  • Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines.

    James R Van Brocklyn;Catherine A Jackson;Dennis K Pearl;Mark S Kotur

  • A Positive Modifier of Spinal Muscular Atrophy in the SMN2 Gene

    Thomas W. Prior;Adrian R. Krainer;Yimin Hua;Kathryn J. Swoboda

  • The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly.

    Elizabeth A Varga;Matthew Pastore;Thomas Prior;Gail E Herman

  • Carrier screening for spinal muscular atrophy

    Thomas W Prior

  • Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly

    Kim L. McBride;Elizabeth A. Varga;Elizabeth A. Varga;Matthew T. Pastore;Matthew T. Pastore;Thomas W. Prior

  • Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis

    Kevin Sweet;Joseph Willis;Xiao Ping Zhou;Carol Gallione

  • Intragenic telSMN mutations: frequency, distribution, evidence of a founder effect, and modification of the spinal muscular atrophy phenotype by cenSMN copy number.

    D. W. Parsons;P. E. McAndrew;Susan T Iannaccone;J. R. Mendell

  • Treatment Algorithm for Infants Diagnosed with Spinal Muscular Atrophy through Newborn Screening.

    Jacqueline Glascock;Jacinda Sampson;Amanda Haidet-Phillips;Anne Connolly

  • The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy (vol 9, pg 333, 2000)

    UR Monani;M Sendtner;DD Coovert;DW Parsons

  • Increasing knowledge of PTEN germline mutations: Two additional patients with autism and macrocephaly†

    Gail E. Herman;Eric Butter;Benedicta Enrile;Matthew Pastore

Frequent Co-Authors

Jerry R. Mendell
Jerry R. Mendell The Ohio State University
Arthur H.M. Burghes
Arthur H.M. Burghes The Ohio State University
John T. Kissel
John T. Kissel The Ohio State University
Clara D. Bloomfield
Clara D. Bloomfield The Ohio State University
Richard A. Larson
Richard A. Larson University of Chicago
Frederick R. Appelbaum
Frederick R. Appelbaum Fred Hutchinson Cancer Research Center
Miguel A. Sanz
Miguel A. Sanz University of Valencia
Konstanze Döhner
Konstanze Döhner University of Ulm
Martin S. Tallman
Martin S. Tallman Northwestern University
Hartmut Döhner
Hartmut Döhner University of Ulm

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