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Neuroscience

D-Index
48
Citations
6468
World Ranking
6275
National Ranking
2732

Overview

Karen S. Wilcox is affiliated with the University of Utah in the United States and has contributed extensively to the fields of Medicine and Neuroscience. Their research output encompasses multiple subfields including Cellular and Molecular Neuroscience, Psychiatry and Mental Health, Molecular Biology, Pediatrics, Perinatology and Child Health, and Cognitive Neuroscience.

The scientist's work covers several main topics related to brain health and neurological disorders. These include:

  • Epilepsy research and treatment
  • Neuroscience and Neuropharmacology Research
  • Pharmacological Effects and Toxicity Studies
  • EEG and Brain-Computer Interfaces
  • Ion channel regulation and function
  • Infectious Encephalopathies and Encephalitis
  • Neuroscience and Neural Engineering

Karen S. Wilcox has published in a variety of venues, with frequent contributions to the following journals and platforms:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Epilepsia
  • IEEE Journal of Solid-State Circuits
  • Brain
  • Epilepsia Open

Notable recent papers include:

  • Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap, 2021, Nature Reviews Neurology
  • Closed-loop stimulation in periods with less epileptiform activity drives improved epilepsy outcomes, 2023, Brain
  • Antiepileptogenesis and disease modification: Progress, challenges, and the path forward-Report of the Preclinical Working Group of the 2018 NINDS-sponsored antiepileptogenesis and disease modification workshop, 2021, Epilepsia Open
  • Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program, 2021, Epilepsia
  • Ultrastructural and functional changes at the tripartite synapse during epileptogenesis in a model of temporal lobe epilepsy, 2020, Experimental Neurology

The scientist has collaborated frequently with a core group of co-authors, including:

  • Cameron S. Metcalf
  • Peter J. West
  • Jeffrey A. Mensah
  • Kristina Johnson
  • Kyle E. Thomson

Best Publications

  • Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat

    GR Christoph;RJ Leonzio;KS Wilcox

  • Mechanisms of Action of Antiepileptic Drugs

    H. Steve White;Misty D. Smith;Karen S. Wilcox

  • Discovery of antiepileptic drugs.

    Misty Smith;Karen S. Wilcox;H. Steve White

  • Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization

    Nanda A. Singh;James F. Otto;E. Jill Dahle;Chris Pappas

  • Paired pulse depression in cultured hippocampal neurons is due to a presynaptic mechanism independent of GABAB autoreceptor activation

    Karen S. Wilcox;Marc A. Dichter

  • Calcium-dependent paired-pulse facilitation of miniature EPSC frequency accompanies depression of EPSCs at hippocampal synapses in culture.

    Dana D. Cummings;Karen S. Wilcox;Marc A. Dichter

  • Imaging Activity in Neurons and Glia with a Polr2a-Based and Cre-Dependent GCaMP5G-IRES-tdTomato Reporter Mouse

    J. Michael Gee;Nathan A. Smith;Fernando R. Fernandez;Michael N. Economo

  • Seizures following picornavirus infection.

    Jane E. Libbey;Nikki J. Kirkman;Matthew C.P. Smith;Tomoko Tanaka

  • Innate but not adaptive immune responses contribute to behavioral seizures following viral infection.

    Nikki J. Kirkman;Jane E. Libbey;Karen S. Wilcox;H. Steve White

  • Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP)

    Brian D. Klein;Catherine A. Jacobson;Cameron S. Metcalf;Misty D. Smith

  • Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus

    D.K. Takahashi;J.R. Vargas;K.S. Wilcox

  • SCN8A encephalopathy: Research progress and prospects

    Miriam H. Meisler;Guy Helman;Michael F. Hammer;Brandy E. Fureman

  • Development of Postinfection Epilepsy After Theiler's Virus Infection of C57BL/6 Mice

    Kerry Ann A. Stewart;Karen S. Wilcox;Robert S. Fujinami;H. Steve White

  • Effects of the anticonvulsant retigabine on cultured cortical neurons: Changes in electroresponsive properties and synaptic transmission

    James F. Otto;Matthew M. Kimball;Karen S. Wilcox

  • The challenge and promise of anti-epileptic therapy development in animal models

    Michele Simonato;Amy R Brooks-Kayal;Jerome Engel;Aristea S Galanopoulou

  • Interleukin-6, Produced by Resident Cells of the Central Nervous System and Infiltrating Cells, Contributes to the Development of Seizures following Viral Infection

    Jane E. Libbey;Nikki J. Kennett;Karen S. Wilcox;H. Steve White

  • Issues related to development of new antiseizure treatments

    Karen S. Wilcox;Tracy Dixon-Salazar;Graeme J. Sills;Elinor Ben-Menachem

  • Hippocampal TNFα Signaling Contributes to Seizure Generation in an Infection-Induced Mouse Model of Limbic Epilepsy.

    Dipan C. Patel;Glenna Wallis;E. Jill Dahle;Pallavi B. McElroy

  • A Spontaneous Mutation Involving Kcnq2 (Kv7.2) Reduces M-Current Density and Spike Frequency Adaptation in Mouse CA1 Neurons

    James F. Otto;Yan Yang;Wayne N. Frankel;H. Steve White

  • Properties of inhibitory and excitatory synapses between hippocampal neurons in very low density cultures.

    Karen S. Wilcox;Jeffrey Buchhalter;Marc A. Dichter

Frequent Co-Authors

H. Steve White
H. Steve White University of Washington
Marc A. Dichter
Marc A. Dichter University of Pennsylvania
John A. White
John A. White Boston University
Mario R. Capecchi
Mario R. Capecchi University of Utah
Michele Simonato
Michele Simonato University of Ferrara
Amy R. Brooks-Kayal
Amy R. Brooks-Kayal University of Colorado Denver
Ilse Smolders
Ilse Smolders Vrije Universiteit Brussel
Mark Leppert
Mark Leppert University of Utah
Julie R. Korenberg
Julie R. Korenberg University of Utah
Wayne N. Frankel
Wayne N. Frankel Columbia University

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