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Neuroscience

D-Index
51
Citations
7470
World Ranking
5609
National Ranking
2485

Overview

Amy R. Brooks-Kayal is affiliated with the University of Colorado Denver in the United States. Their research spans multiple domains within medicine, neuroscience, and molecular biology, with a particular focus on epilepsy and neurological disorders.

The main fields of study for Amy R. Brooks-Kayal include:

  • Medicine
  • Neuroscience
  • Biochemistry, Genetics and Molecular Biology

Their work further subdivides into specific subfields such as:

  • Cellular and Molecular Neuroscience
  • Molecular Biology
  • Psychiatry and Mental health
  • Neurology
  • Pediatrics, Perinatology and Child Health

The research topics explored cover a wide range of themes, notably:

  • Neuroscience and Neuropharmacology Research
  • Epilepsy research and treatment
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Ion channel regulation and function
  • Neonatal and fetal brain pathology
  • Pesticide Exposure and Toxicity
  • Machine Learning in Bioinformatics

Several academic journals have been frequent venues for Amy R. Brooks-Kayal's publications. These include:

  • Neurotherapeutics
  • Nature Reviews Neurology
  • Annals of Neurology
  • Frontiers in Neurology
  • Epilepsy & Behavior

Frequent coauthors collaborating with Amy R. Brooks-Kayal are:

  • Yasmin Cruz Del Angel
  • Jessica Carlsen
  • Marco I. González
  • Jeremy A. MacMahon
  • Donald A. Bruun

Representative recent papers authored or coauthored by Amy R. Brooks-Kayal include:

  • "Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap," 2021, Nature Reviews Neurology
  • "Selective Neuronal Knockout of STAT3 Function Inhibits Epilepsy Progression, Improves Cognition, and Restores Dysregulated Gene Networks in a Temporal Lobe Epilepsy Model," 2023, Annals of Neurology
  • "Altered Protein Profiles During Epileptogenesis in the Pilocarpine Mouse Model of Temporal Lobe Epilepsy," 2021, Frontiers in Neurology
  • "Down-regulation of AMPA receptors and long-term potentiation during early epileptogenesis," 2021, Epilepsy & Behavior
  • "Pediatric Neurology Research in the Twenty-First Century: Status, Challenges, and Future Directions Post-COVID-19," 2020, Pediatric Neurology

Best Publications

  • Selective changes in single cell GABA A receptor subunit expression and function in temporal lobe epilepsy

    Amy R. Brooks-Kayal;Amy R. Brooks-Kayal;Melissa D. Shumate;Hong Jin;Tatiana Y. Rikhter

  • Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

    Pavel Klein;Raymond Dingledine;Eleonora Aronica;Christophe Bernard

  • Targeted Loss of Arx Results in a Developmental Epilepsy Mouse Model and Recapitulates the Human Phenotype in Heterozygous Females

    Eric Marsh;Carl Fulp;Ernest Gomez;Ilya Nasrallah

  • Increased expression of the neuronal glutamate transporter (EAAT3/EAAC1) in hippocampal and neocortical epilepsy.

    Peter B Crino;Hong Jin;Melissa D Shumate;Michael B Robinson

  • BDNF Selectively Regulates GABAA Receptor Transcription by Activation of the JAK/STAT Pathway

    Ingrid V. Lund;Yinghui Hu;YogendraSinh H. Raol;Rebecca S. Benham

  • Epilepsy and autism spectrum disorders: are there common developmental mechanisms?

    Amy Brooks-Kayal

  • Subclinical early posttraumatic seizures detected by continuous EEG monitoring in a consecutive pediatric cohort

    Daniel H. Arndt;Jason T. Lerner;Jason T. Lerner;Joyce H. Matsumoto;Joyce H. Matsumoto;Andranik Madikians

  • Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy

    Amy R. Brooks-Kayal;Kevin G. Bath;Anne T. Berg;Aristea S. Galanopoulou

  • Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy.

    YogendraSinh H Raol;Ingrid V Lund;Sabita Bandyopadhyay;Guojun Zhang

  • Brain-derived Neurotrophic Factor (BDNF)-induced Synthesis of Early Growth Response Factor 3 (Egr3) Controls the Levels of Type A GABA Receptorα4 Subunits in Hippocampal Neurons

    Daniel S. Roberts;Yinghui Hu;Ingrid V. Lund;Amy R. Brooks-Kayal

  • Repeated neonatal handling with maternal separation permanently alters hippocampal GABAA receptors and behavioral stress responses

    Fu-Chun Hsu;Guo-Jun Zhang;Yogendra Sinh H. Raol;Rita J. Valentino

  • Curing epilepsy: progress and future directions.

    Margaret P. Jacobs;Gabrielle G. Leblanc;Amy Brooks-Kayal;Frances E. Jensen

  • Two Tyrosine Residues on the α Subunit Are Crucial for Benzodiazepine Binding and Allosteric Modulation of γ-Aminobutyric Acid A Receptors

    Jahanshah Amin;Amy Brooks-Kayal;David S. Weiss

  • γ-Aminobutyric acidA receptor subunit expression predicts functional changes in hippocampal dentate granule cells during postnatal development

    Amy R. Brooks-Kayal;Amy R. Brooks-Kayal;Melissa D. Shumate;Hong Jin;Tatiana Y. Rikhter

  • Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABAA receptor α4 subunit expression

    D. S. Roberts;Y. H. Raol;S. Bandyopadhyay;I. V. Lund

  • Developmental changes in human gamma-aminobutyric acidA receptor subunit composition.

    A R Brooks-Kayal;D B Pritchett;D B Pritchett

  • Long-term alterations in glutamate receptor and transporter expression following early-life seizures are associated with increased seizure susceptibility

    Guojun Zhang;Yogendra Sinh H. Raol;Fu-Chun Hsu;Amy R. Brooks-Kayal;Amy R. Brooks-Kayal

  • Effects of status epilepticus on hippocampal GABAA receptors are age-dependent

    G Zhang;Y.H Raol;F.-C Hsu;D.A Coulter;D.A Coulter

  • Human Neuronal γ-Aminobutyric AcidA Receptors: Coordinated Subunit mRNA Expression and Functional Correlates in Individual Dentate Granule Cells

    Amy R. Brooks-Kayal;Amy R. Brooks-Kayal;Melissa D. Shumate;Hong Jin;Dean D. Lin

  • The effect of STAT3 inhibition on status epilepticus and subsequent spontaneous seizures in the pilocarpine model of acquired epilepsy.

    H.L. Grabenstatter;Y. Cruz Del Angel;J. Carlsen;M.F. Wempe

  • Epilepsy after early-life seizures can be independent of hippocampal injury

    Yogendra Sinh H. Raol;Elaine C. Budreck;Amy R. Brooks‐Kayal;Amy R. Brooks‐Kayal

Frequent Co-Authors

Douglas A. Coulter
Douglas A. Coulter Children's Hospital of Philadelphia
Brenda E. Porter
Brenda E. Porter Stanford University
Aristea S. Galanopoulou
Aristea S. Galanopoulou Albert Einstein College of Medicine
Michele Simonato
Michele Simonato University of Ferrara
Eric D. Marsh
Eric D. Marsh Children's Hospital of Philadelphia
Asla Pitkänen
Asla Pitkänen University of Eastern Finland
Karen S. Wilcox
Karen S. Wilcox University of Utah
Raman Sankar
Raman Sankar University of California, Los Angeles
Daniel H. Lowenstein
Daniel H. Lowenstein University of California, San Francisco
Elaine H. Zackai
Elaine H. Zackai Children's Hospital of Philadelphia

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