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Biology and Biochemistry

D-Index
56
Citations
11786
World Ranking
14390
National Ranking
6059

Overview

Sanford L. Boye is affiliated with the University of Florida in the United States. Their research contributions focus primarily on biochemistry, genetics, molecular biology, and medicine, with a significant emphasis on molecular biology and genetics as subfields of study.

The scientist's work covers several specialized topics, including:

  • Retinal Development and Disorders
  • Virus-based gene therapy research
  • Retinal Diseases and Treatments
  • Photoreceptor and optogenetics research
  • CRISPR and Genetic Engineering
  • RNA Interference and Gene Delivery
  • Ocular Disorders and Treatments

Boye has collaborated frequently with several colleagues, including Diego Fajardo, Artur V. Cideciyan, Samuel G. Jacobson, and Sean M. Crosson.

Their publications have appeared most frequently in the following venues:

  • Molecular Therapy
  • Molecular Therapy - Methods & Clinical Development
  • bioRxiv (Cold Spring Harbor Laboratory)
  • iScience
  • Human Gene Therapy

Recent papers include the following:

  • Current Clinical Applications of In Vivo Gene Therapy with AAVs, 2020, Molecular Therapy
  • SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration, 2020, eLife
  • Adeno-Associated Virus (AAV) Capsid Stability and Liposome Remodeling During Endo/Lysosomal pH Trafficking, 2020, Viruses
  • Identifying Treatments for Taste and Smell Disorders: Gaps and Opportunities, 2020, Chemical Senses
  • Safety and improved efficacy signals following gene therapy in childhood blindness caused by GUCY2D mutations, 2021, iScience

Best Publications

  • Treatment of Leber Congenital Amaurosis Due to RPE65 Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial

    William W. Hauswirth;Tomas S. Aleman;Shalesh Kaushal;Artur V. Cideciyan

  • Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

    Artur V. Cideciyan;Tomas S. Aleman;Sanford L. Boye;Sharon B. Schwartz

  • Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years

    Samuel G. Jacobson;Artur V. Cideciyan;Ramakrishna Ratnakaram;Elise Heon

  • Current Clinical Applications of In Vivo Gene Therapy with AAVs.

    Jerry R. Mendell;Jerry R. Mendell;Samiah A. Al-Zaidy;Louise R. Rodino-Klapac;Kimberly Goodspeed

  • Human RPE65 Gene Therapy for Leber Congenital Amaurosis: Persistence of Early Visual Improvements and Safety at 1 Year

    Artur V. Cideciyan;William W. Hauswirth;Tomas S. Aleman;Shalesh Kaushal

  • Virally delivered Channelrhodopsin-2 Safely and Effectively Restores Visual Function in Multiple Mouse Models of Blindness

    M Mehdi Doroudchi;Kenneth P Greenberg;Jianwen Liu;Kimberly A Silka

  • A comprehensive review of retinal gene therapy.

    Shannon E Boye;Sanford L Boye;Alfred S Lewin;William W Hauswirth

  • Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa

    William A. Beltran;Artur V. Cideciyan;Alfred S. Lewin;Simone Iwabe

  • Vision 1 year after gene therapy for Leber's congenital amaurosis.

    Artur V. Cideciyan;William W. Hauswirth;Tomas S. Aleman;Shalesh Kaushal

  • Safety of Recombinant Adeno-Associated Virus Type 2–RPE65 Vector Delivered by Ocular Subretinal Injection

    Samuel G. Jacobson;Gregory M. Acland;Gustavo D. Aguirre;Tomas S. Aleman

  • Treatment of retinitis pigmentosa due to MERTK mutations by ocular subretinal injection of adeno-associated virus gene vector: results of a phase I trial

    Nicola G. Ghazi;Emad B. Abboud;Sawsan R. Nowilaty;Hisham Alkuraya

  • Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa.

    Ji-jing Pang;Xufeng Dai;Xufeng Dai;Shannon E Boye;Ilaria Barone

  • Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors

    Christine N. Kay;Renee C. Ryals;George V. Aslanidi;Seok Hong Min

  • Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber’s hereditary optic neuropathy in a mouse model

    Hong Yu;Rajeshwari D. Koilkonda;Tsung Han Chou;Vittorio Porciatti

  • AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation.

    Ji-jing Pang;Sanford L. Boye;Ashok Kumar;Astra Dinculescu

  • Retinal gene therapy with a large MYO7A cDNA using adeno-associated virus

    Vanda S. Lopes;Shannon E. Boye;Carrie M. Louie;Sanford Boye

  • AAV-mediated cone rescue in a naturally occurring mouse model of CNGA3-achromatopsia.

    Ji-jing Pang;Ji-jing Pang;Wen-Tao Deng;Xufeng Dai;Xufeng Dai;Bo Lei

  • The human rhodopsin kinase promoter in an AAV5 vector confers rod- and cone-specific expression in the primate retina.

    Shannon E. Boye;John J. Alexander;Sanford L. Boye;Clark D. Witherspoon

  • Dual Adeno-Associated Virus Vectors Result in Efficient In Vitro and In Vivo Expression of an Oversized Gene, MYO7A

    Frank M. Dyka;Sanford L. Boye;Vince A. Chiodo;William W. Hauswirth

  • Functional and behavioral restoration of vision by gene therapy in the guanylate cyclase-1 (GC1) knockout mouse.

    Shannon E. Boye;Sanford L. Boye;Jijing Pang;Renee Ryals

Frequent Co-Authors

William W. Hauswirth
William W. Hauswirth University of Florida
Vince A. Chiodo
Vince A. Chiodo University of Florida
Samuel G. Jacobson
Samuel G. Jacobson University of Pennsylvania
Artur V. Cideciyan
Artur V. Cideciyan University of Pennsylvania
Gustavo D. Aguirre
Gustavo D. Aguirre University of Pennsylvania
Alfred S. Lewin
Alfred S. Lewin University of Florida
Tomas S. Aleman
Tomas S. Aleman University of Pennsylvania
Bo Chang
Bo Chang University of California, Los Angeles
Paul D. Gamlin
Paul D. Gamlin University of Alabama at Birmingham
Barry J. Byrne
Barry J. Byrne University of Florida

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