D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 82 Citations 29,366 434 World Ranking 10793 National Ranking 5668

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Enzyme

Barry J. Byrne mainly investigates Genetic enhancement, Virology, Internal medicine, Adeno-associated virus and Molecular biology. His work deals with themes such as Fluorodopa, Retinal, Immunology and Pathology, which intersect with Genetic enhancement. His studies deal with areas such as Vector and Plasmid as well as Virology.

Barry J. Byrne interconnects Endocrinology and Cardiology in the investigation of issues within Internal medicine. His biological study spans a wide range of topics, including Pseudotyping, Recombinant virus and Transduction. His Molecular biology research incorporates themes from Luciferase, Gene, RNA-binding protein, Myotonic dystrophy and In vivo.

His most cited work include:

  • Human Mesenchymal Stem Cells Differentiate to a Cardiomyocyte Phenotype in the Adult Murine Heart (2025 citations)
  • Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield (1104 citations)
  • Treatment of Leber Congenital Amaurosis Due to RPE65 Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial (799 citations)

What are the main themes of his work throughout his whole career to date?

Barry J. Byrne mainly focuses on Internal medicine, Genetic enhancement, Disease, Adeno-associated virus and Virology. His studies in Internal medicine integrate themes in fields like Endocrinology and Cardiology. His Genetic enhancement research incorporates elements of Gene expression, Transgene, Bioinformatics, Immunology and Viral vector.

His Disease research is multidisciplinary, incorporating elements of Physical therapy, Pediatrics and Pharmacology. His research on Adeno-associated virus also deals with topics like

  • Transduction and related Gene delivery,
  • In vivo that intertwine with fields like In vitro and Myocyte. His Virology study which covers Recombinant DNA that intersects with Molecular biology.

He most often published in these fields:

  • Internal medicine (28.03%)
  • Genetic enhancement (24.89%)
  • Disease (16.59%)

What were the highlights of his more recent work (between 2016-2021)?

  • Internal medicine (28.03%)
  • Disease (16.59%)
  • Genetic enhancement (24.89%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Internal medicine, Disease, Genetic enhancement, Duchenne muscular dystrophy and Enzyme replacement therapy. Barry J. Byrne has included themes like Endocrinology and Cardiology in his Internal medicine study. His Disease study incorporates themes from Immunology, Immune system and Pediatrics.

The Genetic enhancement study combines topics in areas such as Bioinformatics, Vector, Molecular biology, Virus and Viral vector. The study incorporates disciplines such as Herpes simplex virus and Virology in addition to Vector. The concepts of his Herpes simplex virus study are interwoven with issues in Titer and Adeno-associated virus.

Between 2016 and 2021, his most popular works were:

  • Efficacy and safety of AAV2 gene therapy in children with aromatic L-amino acid decarboxylase deficiency: an open-label, phase 1/2 trial (43 citations)
  • Safety of Intradiaphragmatic Delivery of Adeno-Associated Virus-Mediated Alpha-Glucosidase (rAAV1-CMV-hGAA) Gene Therapy in Children Affected by Pompe Disease (39 citations)
  • A phase 3 randomized placebo-controlled trial of tadalafil for Duchenne muscular dystrophy (34 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Enzyme

His primary scientific interests are in Internal medicine, Genetic enhancement, Enzyme replacement therapy, Adverse effect and Duchenne muscular dystrophy. His Internal medicine research includes elements of Endocrinology, Surgery and Cardiology. His Genetic enhancement research integrates issues from Vector, Molecular biology, Disease, Respiratory system and Weakness.

His work investigates the relationship between Molecular biology and topics such as Herpes simplex virus that intersect with problems in Adeno-associated virus. Many of his studies on Adeno-associated virus involve topics that are commonly interrelated, such as Gene delivery. His Disease study integrates concerns from other disciplines, such as Immune system, Immunology and Newborn screening.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Human Mesenchymal Stem Cells Differentiate to a Cardiomyocyte Phenotype in the Adult Murine Heart

Catalin Toma;Mark F. Pittenger;Kevin S. Cahill;Barry J. Byrne.
Circulation (2002)

3276 Citations

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

S Zolotukhin;B J Byrne;E Mason;I Zolotukhin.
Gene Therapy (1999)

1458 Citations

Treatment of Leber Congenital Amaurosis Due to RPE65 Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial

William W. Hauswirth;Tomas S. Aleman;Shalesh Kaushal;Artur V. Cideciyan.
Human Gene Therapy (2008)

1102 Citations

Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.

Jill W. Miller;Carl R. Urbinati;Patana Teng-umnuay;Myrna G. Stenberg.
The EMBO Journal (2000)

973 Citations

Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization

Maria B. Grant;W. Stratford May;Sergio Caballero;Gary A. J. Brown.
Nature Medicine (2002)

902 Citations

Recombinant human acid α-glucosidase Major clinical benefits in infantile-onset Pompe disease

P. S. Kishnani;D. Corzo;M. Nicolino;B. Byrne.
Neurology (2007)

818 Citations

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

Artur V. Cideciyan;Tomas S. Aleman;Sanford L. Boye;Sharon B. Schwartz.
Proceedings of the National Academy of Sciences of the United States of America (2008)

777 Citations

Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic protein

Paul D. Kessler;Gregory M. Podsakoff;Xiaojuan Chen;Susan A. McQuiston.
Proceedings of the National Academy of Sciences of the United States of America (1996)

768 Citations

Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years

Samuel G. Jacobson;Artur V. Cideciyan;Ramakrishna Ratnakaram;Elise Heon.
Archives of Ophthalmology (2012)

682 Citations

Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors.

Sergei Zolotukhin;Mark Potter;Irene Zolotukhin;Yoshihisa Sakai.
Methods (2002)

631 Citations

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