D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 43 Citations 6,972 118 World Ranking 11332 National Ranking 3145

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Anticonvulsant
  • Biochemistry

James P. Stables mostly deals with Anticonvulsant, Stereochemistry, Chemical synthesis, Pharmacology and Epilepsy. His Anticonvulsant research integrates issues from Oral administration, ED50, Structure–activity relationship, Phenytoin and Carboxamide. His Stereochemistry study integrates concerns from other disciplines, such as Aryl, Isatin and Mechanism of action.

The various areas that he examines in his Chemical synthesis study include Hydrazone, Hydrogen bond, Pharmacophore, Biological activity and Semicarbazone. His Pharmacology research incorporates elements of Neurotoxicity and Hydrazide. James P. Stables combines subjects such as Central nervous system disease and Intensive care medicine with his study of Epilepsy.

His most cited work include:

  • Anticonvulsant activity of Schiff bases of isatin derivatives. (247 citations)
  • Anticonvulsant activity of hydrazones, Schiff and Mannich bases of isatin derivatives. (203 citations)
  • Anticonvulsant properties of various acetylhydrazones, oxamoylhydrazones and semicarbazones derived from aromatic and unsaturated carbonyl compounds. (196 citations)

What are the main themes of his work throughout his whole career to date?

James P. Stables focuses on Anticonvulsant, Stereochemistry, Pharmacology, Chemical synthesis and Neurotoxicity. His Anticonvulsant research is multidisciplinary, relying on both Oral administration, Semicarbazone, Phenytoin and Strychnine. The Stereochemistry study combines topics in areas such as Aryl and Structure–activity relationship.

His Structure–activity relationship research focuses on Cytotoxicity and how it relates to Enone. His Pharmacology research is multidisciplinary, incorporating perspectives in Receptor, Pentylenetetrazol, Sodium channel and Epilepsy. As a member of one scientific family, James P. Stables mostly works in the field of Chemical synthesis, focusing on Amino acid and, on occasion, Seizure threshold.

He most often published in these fields:

  • Anticonvulsant (69.33%)
  • Stereochemistry (52.00%)
  • Pharmacology (34.00%)

What were the highlights of his more recent work (between 2009-2013)?

  • Anticonvulsant (69.33%)
  • Stereochemistry (52.00%)
  • Pharmacology (34.00%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Anticonvulsant, Stereochemistry, Pharmacology, Structure–activity relationship and Neurotoxicity. James P. Stables has included themes like Antiepileptic drug and ED50 in his Anticonvulsant study. His work on Pharmacophore as part of his general Stereochemistry study is frequently connected to Active compound, thereby bridging the divide between different branches of science.

His biological study spans a wide range of topics, including Receptor, Local anesthetic, Antioxidant and Sodium channel. His studies deal with areas such as Pyridine, Active metabolite, Imidazole, Lacosamide and Stereoisomerism as well as Structure–activity relationship. His Neurotoxicity study incorporates themes from Oral administration, Nafimidone, Antimicrobial, Prodrug and Carbamazepine.

Between 2009 and 2013, his most popular works were:

  • Identification of new epilepsy treatments: Issues in preclinical methodology (168 citations)
  • A New Derivative of Valproic Acid Amide Possesses a Broad-spectrum Antiseizure Profile and Unique Activity Against Status Epilepticus and Organophosphate Neuronal Damage (55 citations)
  • Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives. (52 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Biochemistry
  • Internal medicine

His primary areas of study are Anticonvulsant, Stereochemistry, Structure–activity relationship, Lacosamide and Pharmacophore. The concepts of his Anticonvulsant study are interwoven with issues in Prodrug, Pharmacology and Valproic Acid. James P. Stables interconnects Nafimidone, Aryl, Antimicrobial and Active metabolite in the investigation of issues within Stereochemistry.

His Structure–activity relationship study combines topics from a wide range of disciplines, such as Neurotoxicity, Maximal electroshock, Stereoisomerism, Rats sprague dawley and Phenytoin. His Lacosamide study combines topics from a wide range of disciplines, such as Adjuvant, Central nervous system, Neuron and Sodium channel. His research investigates the connection between Pharmacophore and topics such as Design synthesis that intersect with problems in Binding properties, Hydrogen bond and Pyridine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Anticonvulsant activity of Schiff bases of isatin derivatives.

Manjusha Verma;Surendra Nath Pandeya;Krishna Nand Singh;James P Stables.
Acta Pharmaceutica (2004)

477 Citations

Anticonvulsant activity of hydrazones, Schiff and Mannich bases of isatin derivatives.

Seshaiah Krishnan Sridhar;Surendra N Pandeya;James P Stables;Atmakuru Ramesh.
European Journal of Pharmaceutical Sciences (2002)

404 Citations

Anticonvulsant properties of various acetylhydrazones, oxamoylhydrazones and semicarbazones derived from aromatic and unsaturated carbonyl compounds.

Jonathan R Dimmock;Sarvesh C Vashishtha;James P Stables.
European Journal of Medicinal Chemistry (2000)

329 Citations

Synthesis and biological activities of diflunisal hydrazide–hydrazones

S.Güniz Küçükgüzel;Adil Mazi;Fikrettin Sahin;Suzan Öztürk.
European Journal of Medicinal Chemistry (2003)

302 Citations

Design and synthesis of anticonvulsants from a combined phthalimide-GABA-anilide and hydrazone pharmacophore.

Jegadeesan Vaigunda Ragavendran;Dharmarajan Sriram;Sravan Kumar Patel;Ingala Vikram Reddy.
European Journal of Medicinal Chemistry (2007)

270 Citations

Synthesis of some 3-(arylalkylthio)-4-alkyl/aryl-5-(4-aminophenyl)-4H-1,2,4-triazole derivatives and their anticonvulsant activity.

İlkay Küçükgüzel;Ş. Güniz Küçükgüzel;Sevim Rollas;Gülten Ötük-Sanış.
Farmaco (2004)

221 Citations

Synthesis of isatin semicarbazones as novel anticonvulsants--role of hydrogen bonding.

Surendra Nath Pandeya;Ayyannan Senthil Raja;James P. Stables.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences (2002)

214 Citations

(Aryloxy)aryl Semicarbazones and Related Compounds: A Novel Class of Anticonvulsant Agents Possessing High Activity in the Maximal Electroshock Screen

J R Dimmock;R N Puthucode;J M Smith;M Hetherington.
Journal of Medicinal Chemistry (1996)

208 Citations

Synthesis and CNS depressant activity of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones.

Varsha Jatav;Pradeep Mishra;Sushil Kashaw;J.P. Stables.
European Journal of Medicinal Chemistry (2008)

207 Citations

Therapy discovery for pharmacoresistant epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop.

James P. Stables;Ed Bertram;F. E. Dudek;Greg Holmes.
Epilepsia (2003)

202 Citations

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