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Chemistry

D-Index
57
Citations
10522
World Ranking
11187
National Ranking
3052

Overview

James P. Stables is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on the fields of Chemistry and Biochemistry, Genetics and Molecular Biology, with a significant number of publications in these areas.

Their subfields of study include:

  • Organic Chemistry
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Materials Chemistry
  • Spectroscopy

Key topics in their research encompass:

  • Neuroscience and Neuropharmacology Research
  • Synthesis and biological activity
  • Molecular spectroscopy and chirality
  • Chemical Synthesis and Analysis
  • Electrochemical Analysis and Applications
  • Ion channel regulation and function
  • Synthesis of heterocyclic compounds

James P. Stables has contributed papers to various publication venues, with frequent venues including:

  • OPAL (Open@LaTrobe) (La Trobe University)
  • UNC Libraries
  • The Cambridge Structural Database

Notable recent papers authored or coauthored include:

  • Development and Characterization of Novel Derivatives of the Antiepileptic Drug Lacosamide That Exhibit Far Greater Enhancement in Slow Inactivation of Voltage-Gated Sodium Channels, 2020, UNC Libraries
  • Synthesis and Anticonvulsant Activities of ( R )- N -(4'-Substituted)benzyl 2-Acetamido-3-methoxypropionamides, 2020, OPAL (Open@LaTrobe) (La Trobe University)
  • Defining the Structural Parameters That Confer Anticonvulsant Activity by the Site-by-Site Modification of ( R )- N '-Benzyl 2-Amino-3-methylbutanamide, 2020, UNC Libraries
  • Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives, 2021, UNC Libraries
  • Lacosamide Isothiocyanate-Based Agents: Novel Agents To Target and Identify Lacosamide Receptors, 2020, OPAL (Open@LaTrobe) (La Trobe University)

Frequent collaborators in their research work include:

  • Christophe Salomé
  • Harold Kohn
  • Ki Duk Park
  • Pierre Morieux
  • Rihe Liu

Best Publications

  • Anticonvulsant activity of Schiff bases of isatin derivatives.

    Manjusha Verma;Surendra Nath Pandeya;Krishna Nand Singh;James P Stables

  • Anticonvulsant activity of hydrazones, Schiff and Mannich bases of isatin derivatives.

    Seshaiah Krishnan Sridhar;Surendra N Pandeya;James P Stables;Atmakuru Ramesh

  • Anticonvulsant properties of various acetylhydrazones, oxamoylhydrazones and semicarbazones derived from aromatic and unsaturated carbonyl compounds.

    Jonathan R Dimmock;Sarvesh C Vashishtha;James P Stables

  • Synthesis and biological activities of diflunisal hydrazide–hydrazones

    S.Güniz Küçükgüzel;Adil Mazi;Fikrettin Sahin;Suzan Öztürk

  • Design and synthesis of anticonvulsants from a combined phthalimide-GABA-anilide and hydrazone pharmacophore.

    Jegadeesan Vaigunda Ragavendran;Dharmarajan Sriram;Sravan Kumar Patel;Ingala Vikram Reddy

  • Synthesis of some 3-(arylalkylthio)-4-alkyl/aryl-5-(4-aminophenyl)-4H-1,2,4-triazole derivatives and their anticonvulsant activity.

    İlkay Küçükgüzel;Ş. Güniz Küçükgüzel;Sevim Rollas;Gülten Ötük-Sanış

  • Synthesis and CNS depressant activity of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones.

    Varsha Jatav;Pradeep Mishra;Sushil Kashaw;J.P. Stables

  • Synthesis of isatin semicarbazones as novel anticonvulsants--role of hydrogen bonding.

    Surendra Nath Pandeya;Ayyannan Senthil Raja;James P. Stables

  • Synthesis and anticonvulsant activity of 4-bromophenyl substituted aryl semicarbazones.

    Surendra N Pandeya;Perumal Yogeeswari;James P Stables

  • Synthesis and anticonvulsant activities of N-Benzyl-2-acetamidopropionamide derivatives.

    Daeock Choi;James P. Stables;Harold Kohn

  • Synthesis and anticonvulsant activity of sulfonamide derivatives-hydrophobic domain.

    Nadeem Siddiqui;Surendra N. Pandeya;Suroor A. Khan;James Stables

  • Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives.

    H Ucar;K Van derpoorten;S Cacciaguerra;S Spampinato

  • Application of predictive QSAR models to database mining: identification and experimental validation of novel anticonvulsant compounds.

    Min Shen;Cécile Béguin;Alexander Golbraikh;James P. Stables

  • Synthesis of some 1-(2-naphthyl)-2-(imidazole-1-yl)ethanone oxime and oxime ether derivatives and their anticonvulsant and antimicrobial activities.

    Arzu Karakurt;Sevim Dalkara;Meral Özalp;Süheyla Özbey

  • Antagonists of GLU K5 -containing kainate receptors prevent pilocarpine-induced limbic seizures

    Ilse Smolders;Zuner A. Bortolotto;Vernon R. J. Clarke;Ruth Warre

  • Discovery of N-(2,6-dimethylphenyl)-substituted semicarbazones as anticonvulsants: hybrid pharmacophore-based design.

    Perumal Yogeeswari;Dharmarajan Sriram;Rathinasabapathy Thirumurugan;Jegadeesan Vaigunda Raghavendran

  • Synthesis and anticonvulsant activity of enaminones. 4. Investigations on isoxazole derivatives.

    Natalie D Eddington;Donna S Cox;Ralph R Roberts;Raymond J Butcher

  • Synthesis, characterization and anticonvulsant activity of enaminones. Part 6: Synthesis of substituted vinylic benzamides as potential anticonvulsants

    James E. Foster;Jesse M. Nicholson;Raymond Butcher;James P. Stables

  • Synthesis and anticonvulsant activity of enaminones. Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives

    Natalie D Eddington;Donna S Cox;Manoj Khurana;Noha N Salama

  • Design, synthesis and evaluation of novel hydroxyamides as orally available anticonvulsants.

    Hilary A Schenck;Paul W Lenkowski;Indrani Choudhury-Mukherjee;Seong-Hoon Ko

  • Synthesis of Some 3-(Arylalkylthio)-4-alkyl/aryl-5-(4-aminophenyl)-4H-1,2,4-triazole Derivatives and Their Anticonvulsant Activity.

    Ilkay Kuecuekguezel;Gueniz S. Kuecuekguezel;Sevim Rollas;Guelten Oetuek‐Sanis

Frequent Co-Authors

Perumal Yogeeswari
Perumal Yogeeswari Birla Institute of Technology and Science, Pilani
Dharmarajan Sriram
Dharmarajan Sriram Birla Institute of Technology and Science, Pilani
Jan Balzarini
Jan Balzarini KU Leuven
Erik De Clercq
Erik De Clercq Rega Institute for Medical Research
Pierre Gressens
Pierre Gressens Université Paris Cité
H. Steve White
H. Steve White University of Washington
Theresa M. Allen
Theresa M. Allen University of Alberta
Ray J. Butcher
Ray J. Butcher Howard University
Hiroshi Sakagami
Hiroshi Sakagami Meikai University
Edward H. Bertram
Edward H. Bertram University of Virginia

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