D-Index & Metrics Best Publications
Chemistry
India
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 62 Citations 11,773 300 World Ranking 5764 National Ranking 54

Research.com Recognitions

Awards & Achievements

2023 - Research.com Chemistry in India Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Organic chemistry
  • Biochemistry

Perumal Yogeeswari mainly focuses on Stereochemistry, Antibacterial agent, Chemical synthesis, Antimycobacterial and Mycobacterium tuberculosis. His study in the field of Thiazole also crosses realms of Sarcosine. He has researched Antibacterial agent in several fields, including Cycloaddition, Nitrile, Opportunistic infection, Acquired immunodeficiency syndrome and Oxindole.

The concepts of his Chemical synthesis study are interwoven with issues in Lactam, Anticonvulsant, Pharmacophore, Semicarbazone and Pharmacology. His studies deal with areas such as Pyridine, Quinoline, Minimum inhibitory concentration, Biological activity and Aryl as well as Antimycobacterial. His Mycobacterium tuberculosis study combines topics in areas such as In vitro, DNA gyrase, In vivo and Isoniazid.

His most cited work include:

  • Betulinic Acid and Its Derivatives: A Review on their Biological Properties (391 citations)
  • Synthesis and evaluation of anti-HIV activity of isatin β-thiosemicarbazone derivatives (210 citations)
  • Discovery of antimycobacterial spiro-piperidin-4-ones: an atom economic, stereoselective synthesis, and biological intervention. (185 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Stereochemistry, Mycobacterium tuberculosis, Antimycobacterial, In vitro and Combinatorial chemistry. His Stereochemistry research includes themes of Cycloaddition, Cytotoxicity, Aryl, Structure–activity relationship and Chemical synthesis. Perumal Yogeeswari interconnects Biological activity, Semicarbazone and Antibacterial agent in the investigation of issues within Chemical synthesis.

His Mycobacterium tuberculosis research is multidisciplinary, incorporating elements of Isoniazid, Biochemistry, Microbiology and DNA gyrase. His Antimycobacterial research includes elements of Ethambutol, 1,3-Dipolar cycloaddition, Medicinal chemistry, Minimum inhibitory concentration and Mycobacterium tuberculosis H37Rv. Perumal Yogeeswari combines subjects such as Cell culture and In vivo with his study of In vitro.

He most often published in these fields:

  • Stereochemistry (46.07%)
  • Mycobacterium tuberculosis (39.30%)
  • Antimycobacterial (30.35%)

What were the highlights of his more recent work (between 2014-2020)?

  • Stereochemistry (46.07%)
  • Mycobacterium tuberculosis (39.30%)
  • In vitro (23.31%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Stereochemistry, Mycobacterium tuberculosis, In vitro, Combinatorial chemistry and Cytotoxicity. His Stereochemistry study incorporates themes from Antimycobacterial, Triazole, Structure–activity relationship and Click chemistry. His work carried out in the field of Mycobacterium tuberculosis brings together such families of science as DNA gyrase, Biochemistry, Enzyme, Microbiology and IC50.

His biological study spans a wide range of topics, including Pyrazole, Cycloaddition, Carbazole and In vivo. His Combinatorial chemistry study also includes

  • Chromone and Quinoline most often made with reference to Anti tubercular,
  • Molecule together with Aryl. Perumal Yogeeswari focuses mostly in the field of Cytotoxicity, narrowing it down to matters related to Isatin and, in some cases, Azomethine ylide, Oxindole and Medicinal chemistry.

Between 2014 and 2020, his most popular works were:

  • Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives (41 citations)
  • One-pot synthesis of new triazole--Imidazo[2,1-b][1,3,4]thiadiazole hybrids via click chemistry and evaluation of their antitubercular activity. (38 citations)
  • Design and synthesis of novel quinoline-aminopiperidine hybrid analogues as Mycobacterium tuberculosis DNA gyraseB inhibitors. (30 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Organic chemistry
  • Biochemistry

Perumal Yogeeswari mostly deals with Mycobacterium tuberculosis, Stereochemistry, Structure–activity relationship, Biochemistry and In vitro. His Mycobacterium tuberculosis study integrates concerns from other disciplines, such as Thiourea, ATPase, Cycloaddition and DNA gyrase. His Stereochemistry research incorporates elements of Minimum inhibitory concentration, Combinatorial chemistry, Cytotoxicity, Antimycobacterial and Aryl.

His study in Structure–activity relationship is interdisciplinary in nature, drawing from both Amino acid, Cancer cell, Nicotinamide and Binding site. His work on Enzyme, Virtual screening, Type II topoisomerase and Wnt signaling pathway as part of general Biochemistry study is frequently connected to Tankyrases, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His studies in In vitro integrate themes in fields like Indole test, Methyl group, Immunology and In vivo.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Betulinic Acid and Its Derivatives: A Review on their Biological Properties

Perumal Yogeeswari;Dharmarajan Sriram.
Current Medicinal Chemistry (2005)

646 Citations

Synthesis and evaluation of anti-HIV activity of isatin β-thiosemicarbazone derivatives

Tanushree Ratan Bal;Balasubramani Anand;Perumal Yogeeswari;Dharmarajan Sriram.
Bioorganic & Medicinal Chemistry Letters (2005)

363 Citations

Design and synthesis of anticonvulsants from a combined phthalimide-GABA-anilide and hydrazone pharmacophore.

Jegadeesan Vaigunda Ragavendran;Dharmarajan Sriram;Sravan Kumar Patel;Ingala Vikram Reddy.
European Journal of Medicinal Chemistry (2007)

294 Citations

Design, Synthesis, and Structure–Activity Correlations of Novel Dibenzo[b,d]furan, Dibenzo[b,d]thiophene, and N-Methylcarbazole Clubbed 1,2,3-Triazoles as Potent Inhibitors of Mycobacterium tuberculosis

Santhosh Reddy Patpi;Lokesh Pulipati;Perumal Yogeeswari;Dharmarajan Sriram.
Journal of Medicinal Chemistry (2012)

262 Citations

Discovery of antimycobacterial spiro-piperidin-4-ones: an atom economic, stereoselective synthesis, and biological intervention.

Raju Ranjith Kumar;Subbu Perumal;Palaniappan Senthilkumar;Perumal Yogeeswari.
Journal of Medicinal Chemistry (2008)

256 Citations

Synthesis and in vitro and in vivo antimycobacterial activity of isonicotinoyl hydrazones

Dharmarajan Sriram;Perumal Yogeeswari;Kasinathan Madhu.
Bioorganic & Medicinal Chemistry Letters (2005)

241 Citations

Abacavir prodrugs: Microwave-assisted synthesis and their evaluation of anti-HIV activities

Dharmarajan Sriram;Perumal Yogeeswari;Naga Sirisha Myneedu;Vivek Saraswat.
Bioorganic & Medicinal Chemistry Letters (2006)

208 Citations

Synthesis and anticonvulsant activity of 4-bromophenyl substituted aryl semicarbazones.

Surendra N Pandeya;Perumal Yogeeswari;James P Stables.
European Journal of Medicinal Chemistry (2000)

207 Citations

A facile synthesis and antimycobacterial evaluation of novel spiro-pyrido-pyrrolizines and pyrrolidines.

Raju Ranjith Kumar;Subbu Perumal;Palaniappan Senthilkumar;Perumal Yogeeswari.
European Journal of Medicinal Chemistry (2009)

179 Citations

An atom efficient, solvent-free, green synthesis and antimycobacterial evaluation of 2-amino-6-methyl-4-aryl-8-[(E)-arylmethylidene]-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitriles.

Raju Ranjith Kumar;Subbu Perumal;Palaniappan Senthilkumar;Perumal Yogeeswari.
Bioorganic & Medicinal Chemistry Letters (2007)

172 Citations

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