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Chemistry

D-Index
43
Citations
6964
World Ranking
17214
National Ranking
2600

Overview

Hong-Min Liu is affiliated with Zhengzhou University in China and has an extensive research profile in the fields of Biochemistry, Genetics and Molecular Biology, as well as Chemistry. Their work focuses primarily on Molecular Biology and Organic Chemistry, with additional contributions in Materials Chemistry, Cancer Research, and Oncology.

The scientist's research topics cover a range of areas including:

  • Synthesis and biological activity
  • Quinazolinone synthesis and applications
  • Epigenetics and DNA Methylation
  • Synthesis and Biological Evaluation
  • Histone Deacetylase Inhibitors Research
  • Synthesis and Characterization of Heterocyclic Compounds
  • Cancer therapeutics and mechanisms

Hong-Min Liu has contributed to numerous publications in prominent scientific journals. Key recent papers include:

  • Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer (2021) published in Acta Pharmaceutica Sinica B
  • Recent Advances of m6A Demethylases Inhibitors and Their Biological Functions in Human Diseases (2022) published in International Journal of Molecular Sciences
  • Discovery of tertiary amide derivatives incorporating benzothiazole moiety as anti-gastric cancer agents in vitro via inhibiting tubulin polymerization and activating the Hippo signaling pathway (2020) published in European Journal of Medicinal Chemistry
  • Discovery of thiosemicarbazone derivatives as effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors against NDM-1 producing clinical isolates (2020) published in Acta Pharmaceutica Sinica B
  • Annual review of KRAS inhibitors in 2022 (2023) published in European Journal of Medicinal Chemistry

Most publications by Hong-Min Liu have appeared in:

  • European Journal of Medicinal Chemistry
  • Chinese Journal of Organic Chemistry
  • The Cambridge Structural Database
  • Acta Pharmaceutica Sinica B
  • Bioorganic Chemistry

Frequent collaborators include Qiurong Zhang, Yu Ke, Jiaxin Zheng, Lihong Shan, and Liying Ma, reflecting a consistent pattern of coauthorship over multiple publications.

Best Publications

  • Spirooxindoles: Promising scaffolds for anticancer agents.

    Bin Yu;De-Quan Yu;Hong-Min Liu

  • Design and synthesis of novel 1,2,3-triazole-dithiocarbamate hybrids as potential anticancer agents.

    Ying-Chao Duan;Yong-Cheng Ma;En Zhang;Xiao-Jing Shi

  • Triazole–Dithiocarbamate Based Selective Lysine Specific Demethylase 1 (LSD1) Inactivators Inhibit Gastric Cancer Cell Growth, Invasion, and Migration

    Yi-Chao Zheng;Ying-Chao Duan;Jin-Lian Ma;Rui-Min Xu

  • Equilibrium biosorption isotherm for lead ion on chaff

    Unknown

  • A Systematic Review of Histone Lysine-Specific Demethylase 1 and Its Inhibitors.

    Yi-Chao Zheng;Jinlian Ma;Zhiru Wang;Jinfeng Li

  • Chemical molecular-based approach to overcome multidrug resistance in cancer by targeting P-glycoprotein (P-gp).

    Hang Zhang;Haiwei Xu;Charles R. Ashby;Yehuda G. Assaraf

  • Isolation and structure elucidation of gymnemic acids, antisweet principles of Gymnema sylvestre.

    Hong Min Liu;Fumiyuki Kiuchi;Yoshisuke Tsuda

  • Discovery of orally active anticancer candidate CFI-400945 derived from biologically promising spirooxindoles: success and challenges.

    Bin Yu;Zhiqiang Yu;Ping-Ping Qi;De-Quan Yu

  • Design, Synthesis, and Structure–Activity Relationship of Novel LSD1 Inhibitors Based on Pyrimidine–Thiourea Hybrids As Potent, Orally Active Antitumor Agents

    Li-Ying Ma;Yi-Chao Zheng;Sai-Qi Wang;Bo Wang

  • Design, synthesis and antiproliferative activity studies of novel 1,2,3-triazole–dithiocarbamate–urea hybrids

    Ying-Chao Duan;Yi-Chao Zheng;Xiao-Chen Li;Meng-Meng Wang

  • Targeting Brd4 for cancer therapy: inhibitors and degraders.

    Yingchao Duan;Yuanyuan Guan;Wenping Qin;Xiaoyu Zhai

  • Synthesis and biological evaluation of novel steroidal[17,16-d][1,2,4]triazolo[1,5-a]pyrimidines.

    Li-Hua Huang;Yong-Fei Zheng;Yong-Zheng Lu;Chuan-Jun Song

  • Natural Product-Derived Spirooxindole Fragments Serve as Privileged Substructures for Discovery of New Anticancer Agents

    Bin Yu;Yi-Chao Zheng;Xiao-Jing Shi;Ping-Ping Qi

  • Design and synthesis of novel 1,2,3-triazole-pyrimidine hybrids as potential anticancer agents.

    Li-Ying Ma;Lu-Ping Pang;Bo Wang;Miao Zhang

  • p-Coumaroyltriacetic acid synthase, a new homologue of chalcone synthase, from Hydrangea macrophylla var. thunbergii.

    Takumi Akiyama;Masaaki Shibuya;Hong-Min Liu;Yutaka Ebizuka

  • High Incidence and Endemic Spread of NDM-1-Positive Enterobacteriaceae in Henan Province, China

    Shangshang Qin;Ying Fu;Qijing Zhang;Hui Qi

  • Design and synthesis of novel 1,2,3-triazole-pyrimidine-urea hybrids as potential anticancer agents.

    Li-Ying Ma;Bo Wang;Lu-Ping Pang;Miao Zhang

  • Evoking picomolar binding in RNA by a single phosphorodithioate linkage.

    N. Dinuka Abeydeera;Martin Egli;Nehemiah Cox;Karen Mercier

  • Synthesis of andrographolide derivatives : A new family of α-glucosidase inhibitors

    Hai-Wei Xu;Gui-Fu Dai;Gai-Zhi Liu;Jun-Feng Wang

  • USP7: Novel Drug Target in Cancer Therapy

    Zhiru Wang;Wenting Kang;Yinghua You;Jingru Pang

  • Synthesis and biological evaluation of coumarin–1,2,3-triazole–dithiocarbamate hybrids as potent LSD1 inhibitors

    Xian-Wei Ye;Yi-Chao Zheng;Ying-Chao Duan;Meng-Meng Wang

  • Design and stereoselective synthesis of novel isosteviol-fused pyrazolines and pyrazoles as potential anticancer agents.

    Song-Lin Zhu;Ya Wu;Ya Wu;Cong-Jun Liu;Chang-Yong Wei

  • Efficient synthesis of new antiproliferative steroidal hybrids using the molecular hybridization approach

    Bin Yu;Ping-Ping Qi;Xiao-Jing Shi;Ruilei Huang

  • Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer.

    Ying Liu;Zan Song;Yajie Liu;Xubin Ma

  • Chemical constituents from Mahkota dewa.

    Yan-Bing Zhang;Xiang-Jun Xu;Hong-Min Liu

  • Synthesis and in vitro antitumor activity of new butenolide-containing dithiocarbamates

    Xiao-Juan Wang;Hai-Wei Xu;Lin-Lin Guo;Jia-Xin Zheng

  • Design, synthesis and antiproliferative activity studies of novel dithiocarbamate-chalcone derivates.

    Dong-Jun Fu;Sai-Yang Zhang;Ying-Chao Liu;Li Zhang

  • Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway

    Sai-Qi Wang;Cong Wang;Li-Ming Chang;Kai-Rui Zhou

  • Design, synthesis and biological evaluation of [1,2,4]triazolo[1,5-a]pyrimidines as potent lysine specific demethylase 1 (LSD1/KDM1A) inhibitors.

    Shuai Wang;Li-Jie Zhao;Yi-Chao Zheng;Dan-Dan Shen

  • Biotransformation of dehydroepiandrosterone (DHEA) with Penicillium griseopurpureum Smith and Penicillium glabrum (Wehmer) Westling.

    Li-Hua Huang;Juan Li;Gong Xu;Xiang-Hua Zhang

  • Synthesis and anticancer activities of novel 1,2,4-triazolo[3,4-a]phthalazine derivatives.

    Deng-Qi Xue;Xu-Yao Zhang;Chao-Jie Wang;Li-Ying Ma

  • Design, Synthesis and Structure-Activity Relationships of Novel Chalcone-1,2,3-triazole-azole Derivates as Antiproliferative Agents

    Sai-Yang Zhang;Dong-Jun Fu;Xiao-Xin Yue;Ying-Chao Liu

  • Design and synthesis of formononetin-dithiocarbamate hybrids that inhibit growth and migration of PC-3 cells via MAPK/Wnt signaling pathways.

    Dong-Jun Fu;Li Zhang;Jian Song;Ruo-Wang Mao

Frequent Co-Authors

Zhe-Sheng Chen
Zhe-Sheng Chen St. John's University
Shaomeng Wang
Shaomeng Wang University of Michigan–Ann Arbor
Yufen Zhao
Yufen Zhao Xiamen University
Dan Mercola
Dan Mercola University of California, Irvine
Andreas Bender
Andreas Bender University of Cambridge

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